Glycocalyx engineering with heparan sulfate mimetics attenuates Wnt activity during adipogenesis to promote glucose uptake and metabolism.

Autor: Trieger GW; Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, California, USA; Department of Medicine, Division of Endocrinology and Metabolism, University of California, San Diego, La Jolla, California, USA., Pessentheiner AR; Department of Medicine, Division of Endocrinology and Metabolism, University of California, San Diego, La Jolla, California, USA., Purcell SC; Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, California, USA., Green CR; Department of Bioengineering, University of California, San Diego, La Jolla, California, USA., DeForest N; Department of Medicine, Division of Endocrinology and Metabolism, University of California, San Diego, La Jolla, California, USA., Willert K; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, California, USA., Majithia AR; Department of Medicine, Division of Endocrinology and Metabolism, University of California, San Diego, La Jolla, California, USA; Department of Pediatrics, University of California, San Diego, La Jolla, California, USA., Metallo CM; Department of Bioengineering, University of California, San Diego, La Jolla, California, USA., Godula K; Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, California, USA; Glycobiology Research and Training Center, University of California, San Diego, La Jolla, California, USA. Electronic address: kgodula@ucsd.edu., Gordts PLSM; Department of Medicine, Division of Endocrinology and Metabolism, University of California, San Diego, La Jolla, California, USA; Glycobiology Research and Training Center, University of California, San Diego, La Jolla, California, USA. Electronic address: pgordts@health.ucsd.edu.

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2023 May; Vol. 299 (5), pp. 104611. Date of Electronic Publication: 2023 Mar 15.

Efficient Synthesis of Heparinoid Bioconjugates for Tailoring FGF2 Activity at the Stem Cell-Matrix Interface.

Autor: Trieger GW; Department of Chemistry and Biochemistry , University of California San Diego , 9500 Gilman Drive , La Jolla , California 92093-0358 , United States., Verespy S 3rd; Department of Chemistry and Biochemistry , University of California San Diego , 9500 Gilman Drive , La Jolla , California 92093-0358 , United States., Gordts PLSM, Godula K; Department of Chemistry and Biochemistry , University of California San Diego , 9500 Gilman Drive , La Jolla , California 92093-0358 , United States.

Publikováno v: Bioconjugate chemistry [Bioconjug Chem] 2019 Mar 20; Vol. 30 (3), pp. 833-840. Date of Electronic Publication: 2019 Feb 08.

Glycocalyx remodeling with proteoglycan mimetics promotes neural specification in embryonic stem cells.

Autor: Huang ML; Department of Chemistry and Biochemistry, University of California , San Diego, California 92093-0358, United States., Smith RA, Trieger GW, Godula K

Publikováno v: Journal of the American Chemical Society [J Am Chem Soc] 2014 Jul 30; Vol. 136 (30), pp. 10565-8. Date of Electronic Publication: 2014 Jul 17.