Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Tricia L. Nilles"'
Publikováno v:
Immunity & Ageing, Vol 19, Iss 1, Pp 1-14 (2022)
Abstract Background Chronic cytomegalovirus (CMV) infection has been postulated as a driver of chronic inflammation that has been associated with frailty and other age-related conditions in both HIV-infected (HIV+) and -uninfected (HIV-) people. Meth
Externí odkaz:
https://doaj.org/article/34dca675686d4c38be52c555f4fbaacd
Autor:
Jenell S, Coleman, Clarissa P, Diniz, Edward J, Fuchs, Mark A, Marzinke, Wutyi, Aung, Rahul P, Bakshi, Homayoon, Farzadegan, Jay H, Bream, Tricia L, Nilles, Sherry, Hudson, Namandjé N, Bumpus, George J, Schwartz, Michael A, Rosenblum, James F, Rooney, Craig W, Hendrix
Publikováno v:
JAIDS Journal of Acquired Immune Deficiency Syndromes. 92:89-96
Depot medroxyprogesterone acetate (DMPA) is a widely used contraceptive method. HIV pre-exposure prophylaxis with emtricitabine and tenofovir disoproxil fumarate (F/TDF) is highly effective in reducing HIV acquisition in women. We sought to determine
Autor:
Runzhi Wang, Charlotte A. Gaydos, Jay H. Bream, Jenell S. Coleman, Maria Trent, Tricia L. Nilles, Kathryn A. Carson
Publikováno v:
Sex Transm Dis
BACKGROUND: Mycoplasma genitalium (MG) is a prevalent sexually transmitted infection, but little is known about the associated inflammatory signatures in the genital tract of adolescents and young adult (AYA) women. METHODS: AYA women age 13 to 24 we
Publikováno v:
Immunityageing : IA. 19(1)
Background Chronic cytomegalovirus (CMV) infection has been postulated as a driver of chronic inflammation that has been associated with frailty and other age-related conditions in both HIV-infected (HIV+) and -uninfected (HIV-) people. Methods To st
Autor:
Adit Dhummakupt, Thuy Anderson, Allison L. Agwu, Jessica H. Rubens, Bareng A. S. Nonyane, Lilly V. Siems, R. Brad Jones, Deborah Persaud, Laura Powell, Tricia L. Nilles, Vicki Tepper, Aleisha Collinson-Streng
Publikováno v:
JCI Insight. 5
The HIV latent reservoir in resting memory CD4(+) T cells precludes cure. Therapeutics to reactivate and eliminate this reservoir are in clinical trials in adults, but not yet in pediatric populations. We determined, ex vivo, the inducibility of the
Autor:
Tricia L. Nilles, Nikolas Wada, Susan Langan, Shane Deng, Jay H. Bream, Ruibin Wang, Joseph B. Margolick, Huifen Li, Sean X. Leng
Publikováno v:
The Journal of Infectious Diseases. 218:249-258
BACKGROUND: Both aging and treated human immunodeficiency virus (HIV)-infected populations exhibit low-level chronic immune activation of unknown etiology, which correlates with morbidity and mortality. Cytomegalovirus (CMV) infection is common in bo
Both aging and treated HIV-infected populations exhibit chronic inflammation and immune activation (CIIA) contributing to increased morbidity and mortality. Chronic cytomegalovirus (CMV) infection is common and induces strong T-cell responses in both
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::493829a19da8f9b7482d212c86672bd3
https://europepmc.org/articles/PMC6227507/
https://europepmc.org/articles/PMC6227507/
Publikováno v:
Journal of Virology. 88:4711-4720
17β-Estradiol (E2) treatment limits the pathology associated with pulmonary diseases caused by pathogens, allergens, and asthma, partly by reducing the production of proinflammatory cytokines and chemokines. To test the hypothesis that E2 protects a
Autor:
Andrew W. Sylwester, Jay H. Bream, Louis J. Picker, Sean X. Leng, Tricia L. Nilles, Hanhvy T. Bui, Susan Langan, Joseph B. Margolick, Huifen Li
Publikováno v:
The Journal of Infectious Diseases. 210:400-404
Increasing evidence suggests that chronic cytomegalovirus (CMV) infection significantly impacts T-cell immunity in human immunodeficiency virus (HIV) infection and aging [1–3]. Most of this evidence consists of analysis of T cells specific to epito
Publikováno v:
Journal of immunological methods. 431
The role of CD4(+) regulatory T cells (Tregs) and their subsets during HIV infection is controversial. Cryopreserved peripheral blood mononuclear cells (PBMC) are an important source for assessing number and function of Tregs. However, it is unknown