Carbonyl Yields in Cigars under Three Smoking Regimens Using a Linear Smoking Machine

Autor: Mimy Young, Charles Feng, Todd Cecil, Tricia L. Johnson

Publikováno v: Chemical research in toxicology.

This study used standard linear smoking machines and puffing protocols to generate data on carbonyl yields in mainstream smoke from 11 unfiltered sheet-wrapped cigars (SWC), seven leaf-wrapped cigars (LWC), and two Kentucky reference cigarettes (3R4F

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc9f8f31b9b0cf9d681f925ec8068fa4
https://pubmed.ncbi.nlm.nih.gov/36602460

Quinazolines as cyclin dependent kinase inhibitors

Autor: Jie Liu, John F. Boylan, Chong-Hwan Chang, Thais M. Sielecki, Haiying Chen, Robert H. Grafstrom, Angela Smallwood, Catherine R. Burton, Michael D. Boisclair, Steven P. Seitz, Tricia L. Johnson, Sarah Cox, George L. Trainor, Pamela A. Benfield, Jodi K. Muckelbauer

Publikováno v: Bioorganic & Medicinal Chemistry Letters. 11:1157-1160

Quinazolines have been identified as inhibitors of CDK4/D1 and CDK2/E. Aspects of the SAR were investigated using solution-phase, parallel synthesis. An X-ray crystal structure was obtained of quinazoline 51 bound in CDK2 and key interactions within

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6ad1b9deac14818da4c2f1d31294004
https://doi.org/10.1016/s0960-894x(01)00185-8

Multi-year Study of PAHs in Mainstream Cigarette Smoke.

Autor: Hearn BA; Bryan A. Hearn, Research Chemist, National Center for Environmental Health, US Centers for Disease Control and Prevention, Atlanta, GA. Yan S. Ding, Health Scientist, National Center for Environmental Health, US Centers for Disease Control and Prevention, Atlanta, GA. Clifford H. Watson, Lead Research Chemist, National Center for Environmental Health, US Centers for Disease Control and Prevention, Atlanta, GA. Tricia L. Johnson, Chemist, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Getie Zewdie, Mathematical Statistician, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Jeannie H. Jeong-Im, Review Chemist, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Matthew J. Walters, Deputy Division Director, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Matthew R. Holman, Director, Office of Science, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. C. George Rochester, Chief Statistician, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD., Ding YS; Bryan A. Hearn, Research Chemist, National Center for Environmental Health, US Centers for Disease Control and Prevention, Atlanta, GA. Yan S. Ding, Health Scientist, National Center for Environmental Health, US Centers for Disease Control and Prevention, Atlanta, GA. Clifford H. Watson, Lead Research Chemist, National Center for Environmental Health, US Centers for Disease Control and Prevention, Atlanta, GA. Tricia L. Johnson, Chemist, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Getie Zewdie, Mathematical Statistician, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Jeannie H. Jeong-Im, Review Chemist, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Matthew J. Walters, Deputy Division Director, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Matthew R. Holman, Director, Office of Science, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. C. George Rochester, Chief Statistician, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD., Watson CH; Bryan A. Hearn, Research Chemist, National Center for Environmental Health, US Centers for Disease Control and Prevention, Atlanta, GA. Yan S. Ding, Health Scientist, National Center for Environmental Health, US Centers for Disease Control and Prevention, Atlanta, GA. Clifford H. Watson, Lead Research Chemist, National Center for Environmental Health, US Centers for Disease Control and Prevention, Atlanta, GA. Tricia L. Johnson, Chemist, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Getie Zewdie, Mathematical Statistician, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Jeannie H. Jeong-Im, Review Chemist, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Matthew J. Walters, Deputy Division Director, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Matthew R. Holman, Director, Office of Science, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. C. George Rochester, Chief Statistician, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD., Johnson TL; Bryan A. Hearn, Research Chemist, National Center for Environmental Health, US Centers for Disease Control and Prevention, Atlanta, GA. Yan S. Ding, Health Scientist, National Center for Environmental Health, US Centers for Disease Control and Prevention, Atlanta, GA. Clifford H. Watson, Lead Research Chemist, National Center for Environmental Health, US Centers for Disease Control and Prevention, Atlanta, GA. Tricia L. Johnson, Chemist, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Getie Zewdie, Mathematical Statistician, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Jeannie H. Jeong-Im, Review Chemist, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Matthew J. Walters, Deputy Division Director, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Matthew R. Holman, Director, Office of Science, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. C. George Rochester, Chief Statistician, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD., Zewdie G; Bryan A. Hearn, Research Chemist, National Center for Environmental Health, US Centers for Disease Control and Prevention, Atlanta, GA. Yan S. Ding, Health Scientist, National Center for Environmental Health, US Centers for Disease Control and Prevention, Atlanta, GA. Clifford H. Watson, Lead Research Chemist, National Center for Environmental Health, US Centers for Disease Control and Prevention, Atlanta, GA. Tricia L. Johnson, Chemist, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Getie Zewdie, Mathematical Statistician, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Jeannie H. Jeong-Im, Review Chemist, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Matthew J. Walters, Deputy Division Director, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Matthew R. Holman, Director, Office of Science, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. C. George Rochester, Chief Statistician, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD., Jeong-Im JH; Bryan A. Hearn, Research Chemist, National Center for Environmental Health, US Centers for Disease Control and Prevention, Atlanta, GA. Yan S. Ding, Health Scientist, National Center for Environmental Health, US Centers for Disease Control and Prevention, Atlanta, GA. Clifford H. Watson, Lead Research Chemist, National Center for Environmental Health, US Centers for Disease Control and Prevention, Atlanta, GA. Tricia L. Johnson, Chemist, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Getie Zewdie, Mathematical Statistician, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Jeannie H. Jeong-Im, Review Chemist, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Matthew J. Walters, Deputy Division Director, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Matthew R. Holman, Director, Office of Science, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. C. George Rochester, Chief Statistician, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD., Walters MJ; Bryan A. Hearn, Research Chemist, National Center for Environmental Health, US Centers for Disease Control and Prevention, Atlanta, GA. Yan S. Ding, Health Scientist, National Center for Environmental Health, US Centers for Disease Control and Prevention, Atlanta, GA. Clifford H. Watson, Lead Research Chemist, National Center for Environmental Health, US Centers for Disease Control and Prevention, Atlanta, GA. Tricia L. Johnson, Chemist, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Getie Zewdie, Mathematical Statistician, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Jeannie H. Jeong-Im, Review Chemist, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Matthew J. Walters, Deputy Division Director, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Matthew R. Holman, Director, Office of Science, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. C. George Rochester, Chief Statistician, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD., Holman MR; Bryan A. Hearn, Research Chemist, National Center for Environmental Health, US Centers for Disease Control and Prevention, Atlanta, GA. Yan S. Ding, Health Scientist, National Center for Environmental Health, US Centers for Disease Control and Prevention, Atlanta, GA. Clifford H. Watson, Lead Research Chemist, National Center for Environmental Health, US Centers for Disease Control and Prevention, Atlanta, GA. Tricia L. Johnson, Chemist, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Getie Zewdie, Mathematical Statistician, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Jeannie H. Jeong-Im, Review Chemist, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Matthew J. Walters, Deputy Division Director, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Matthew R. Holman, Director, Office of Science, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. C. George Rochester, Chief Statistician, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD., Rochester CG; Bryan A. Hearn, Research Chemist, National Center for Environmental Health, US Centers for Disease Control and Prevention, Atlanta, GA. Yan S. Ding, Health Scientist, National Center for Environmental Health, US Centers for Disease Control and Prevention, Atlanta, GA. Clifford H. Watson, Lead Research Chemist, National Center for Environmental Health, US Centers for Disease Control and Prevention, Atlanta, GA. Tricia L. Johnson, Chemist, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Getie Zewdie, Mathematical Statistician, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Jeannie H. Jeong-Im, Review Chemist, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Matthew J. Walters, Deputy Division Director, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Matthew R. Holman, Director, Office of Science, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. C. George Rochester, Chief Statistician, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD.

Publikováno v: Tobacco regulatory science [Tob Regul Sci] 2018 May; Vol. 4 (3), pp. 96-106.