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pro vyhledávání: '"Tricia Elkinton"'
Autor:
Amr Alaarg, Rajeev Menon, David Rizzo, Yemin Liu, Jeffrey Bien, Tricia Elkinton, Timothy Grieme, Lutz R. Asmus, Ahmed Hamed Salem
Publikováno v:
Clinical and Translational Science, Vol 15, Iss 1, Pp 244-254 (2022)
Abstract This work presents an end‐to‐end approach for assessing the absolute bioavailability of highly hydrophobic, poorly water‐soluble compounds that exhibit high nonspecific binding using venetoclax as a model drug. The approach utilizes a
Externí odkaz:
https://doaj.org/article/1e832f7aa4554f67b6efa91901c6dfd9
Autor:
Rajeev M. Menon, Timothy A. Grieme, Yemin Liu, Ahmed Salem, Jeffrey Bien, David Rizzo, Lutz R. Asmus, Tricia Elkinton, Amr Alaarg
Publikováno v:
Clinical and Translational Science
Clinical and Translational Science, Vol 15, Iss 1, Pp 244-254 (2022)
Clinical and Translational Science, Vol 15, Iss 1, Pp 244-254 (2022)
This work presents an end‐to‐end approach for assessing the absolute bioavailability of highly hydrophobic, poorly water‐soluble compounds that exhibit high nonspecific binding using venetoclax as a model drug. The approach utilizes a stable la