Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Tricia Chen"'
Autor:
Jason Szeto, Aruun Beharry, Tricia Chen, Eric Zholumbetov, Emilie Daigneault, Marin Ming, Iain Lounsbury, Nelson Eng, Nemika Thangavadivel, Robbie Jin, Aurélie Denis-Jacquot, Bahram Behnam Azad, Meili Li, Diana Keizner, Marcus Liu, Sophia S. F. Lee, Kai He, Beata Gajewska
Publikováno v:
Vaccines, Vol 11, Iss 2, p 275 (2023)
There is increasing interest to replace animal-based potency assays used routinely to test vaccines, since they are highly variable, are costly, and present ethical concerns. The development of relevant in vitro assays is part of the solution. Using
Externí odkaz:
https://doaj.org/article/947b209ed417416e82d89ff044c1a03a
Autor:
Camille Houy, Marin Ming, Luciano Ettorre, Robbie Jin, Nemika Thangavadivel, Tricia Chen, Jin Su, Beata Gajewska
Publikováno v:
Vaccines, Vol 10, Iss 5, p 775 (2022)
In the vaccine industry, multiple physicochemical, immunological, in vitro and in vivo analytical methods are applied throughout the manufacturing process to characterize and monitor the quality of vaccines. Presented here is the Single Epitope Antig
Externí odkaz:
https://doaj.org/article/8fb2450be57c4a3ea250d6e45148c860
Publikováno v:
PLoS Pathogens, Vol 4, Iss 7, p e1000100 (2008)
Herpesviruses are large, ubiquitous DNA viruses with complex host interactions, yet many of the proteins encoded by these viruses have not been functionally characterized. As a first step in functional characterization, we determined the subcellular
Externí odkaz:
https://doaj.org/article/f0e1da770bcf47098de31530508a0b2d
Publikováno v:
Biotechnology journalREFERENCES. 17(2)
Background Epitope mapping is an increasingly important aspect of biotherapeutic and vaccine development. Recent advances in therapeutic antibody design and production have enabled candidate mAbs to be identified at a rapidly increasing rate, resulti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5064a0b7b0b8836ef2c9e183cd00007a
https://pubmed.ncbi.nlm.nih.gov/34747565
https://pubmed.ncbi.nlm.nih.gov/34747565
Background: Epitope mapping is an increasingly important aspect of biotherapeutic and vaccine development. Recent advances in therapeutic antibody design and production has enabled candidate mAbs to be identified at a rapidly increasing rate resultin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::788bc68b785ba1c0eb523afe2cdb449e
https://doi.org/10.22541/au.162742356.68704724/v1
https://doi.org/10.22541/au.162742356.68704724/v1
Autor:
Shaolong Zhu, Peter Liuni, Bruce Carpick, D. Andrew James, Tricia Chen, Luciano Ettorre, Jason Szeto, Derek J. Wilson
Publikováno v:
Biochemistry. 58:646-656
The diphtheria toxoid (DT) antigen is one of the major components in pediatric and booster combination vaccines and is known to raise a protective humoral immune response upon vaccination. However, a structurally resolved analysis of diphtheria toxin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c36f847edb6d75185efe75b958a1dbbc
https://doi.org/10.1021/acs.biochem.8b01123
https://doi.org/10.1021/acs.biochem.8b01123
Publikováno v:
Journal of immunological methods. 452
We have developed an accurate, precise and stability-indicating flow cytometry (FC) based assay to directly measure antigenicity of H4 protein (also known as HyVac4) in a vaccine formulation of H4-IC31, without desorbing the H4 protein from the IC31
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c8447212727e9790529603d4f2af059
https://pubmed.ncbi.nlm.nih.gov/29056527
https://pubmed.ncbi.nlm.nih.gov/29056527
Publikováno v:
Journal of Virology. 78:329-339
The baculovirus protein P143 is essential for viral DNA replication in vivo, likely as a DNA helicase. We have demonstrated that another viral protein, LEF-3, first described as a single-stranded DNA binding protein, is required for transporting P143
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d065027b15f494934d163478c74b7910
https://doi.org/10.1128/jvi.78.1.329-339.2004
https://doi.org/10.1128/jvi.78.1.329-339.2004
Autor:
Christian Burks, Megan Domagala, Bryan Beattie, Laura Lea Murley, Rosanne Thalakada, Daniel Mamelak, Grant McFadden, Vicki Athanasopoulos, Nicole Brufatto, David C. Johnson, Mian Gao, Lori Frappier, Tricia Chen
Publikováno v:
Journal of proteome research. 4(6)
We have developed a high-throughput system for generating baculoviruses and testing the expression, solubility, and affinity column purification of encoded proteins. We have used this system to generate baculoviruses for and analyze the expression of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ce2614a7165adc5335c3b14d18028a2
https://pubmed.ncbi.nlm.nih.gov/16335970
https://pubmed.ncbi.nlm.nih.gov/16335970
Publikováno v:
Journal of virology. 78(1)
The baculovirus protein P143 is essential for viral DNA replication in vivo, likely as a DNA helicase. We have demonstrated that another viral protein, LEF-3, first described as a single-stranded DNA binding protein, is required for transporting P143
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2a823e96c378fe63583b8dde9ffd93cb
https://pubmed.ncbi.nlm.nih.gov/14671115
https://pubmed.ncbi.nlm.nih.gov/14671115