Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Tricia A. Windgassen"'
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0255409 (2021)
DNA replication complexes (replisomes) frequently encounter barriers that can eject them prematurely from the genome. To avoid the lethality of incomplete DNA replication that arises from these events, bacteria have evolved "DNA replication restart"
Externí odkaz:
https://doaj.org/article/5580c6f10c3a463886ed0e2cb386b665
Autor:
Jason Saba, Xien Yu Chua, Tatiana V Mishanina, Dhananjaya Nayak, Tricia A Windgassen, Rachel Anne Mooney, Robert Landick
Publikováno v:
eLife, Vol 8 (2019)
Transcriptional pausing underlies regulation of cellular RNA biogenesis. A consensus pause sequence that acts on RNA polymerases (RNAPs) from bacteria to mammals halts RNAP in an elemental paused state from which longer-lived pauses can arise. Althou
Externí odkaz:
https://doaj.org/article/24639bf2d563493da405524c788c5de8
Publikováno v:
Mol Microbiol
In Escherichia coli, PriA, PriB, PriC, and DnaT proteins mediate three pathways for Replication Restart called PriA-PriB, PriA-PriC and PriC. PriA is crucial for two of the three pathways. Its absence leads to slow growth, high basal levels of SOS ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d2c9da51a1920ebd8af10236966186d
https://doi.org/10.1111/mmi.14802
https://doi.org/10.1111/mmi.14802
Publikováno v:
Journal of Biological Chemistry. 294:2801-5614
DNA helicases are motor proteins that couple the chemical energy of nucleoside triphosphate hydrolysis to the mechanical functions required for DNA unwinding. Studies of several helicases have identified strand-separating “pin” structures that ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12ecea143f00e092bd2040b25ecb971f
https://doi.org/10.1074/jbc.ra118.006870
https://doi.org/10.1074/jbc.ra118.006870
Autor:
Tricia A. Windgassen, Tatiana V. Mishanina, Xien Yu Chua, Rachel A. Mooney, Robert Landick, Jason Saba, Dhananjaya Nayak
Publikováno v:
eLife
eLife, Vol 8 (2019)
eLife, Vol 8 (2019)
Transcriptional pausing underlies regulation of cellular RNA biogenesis. A consensus pause sequence that acts on RNA polymerases (RNAPs) from bacteria to mammals halts RNAP in an elemental paused state from which longer-lived pauses can arise. Althou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e33fd8bafe75399cb9ac3fd0518a18c
https://doi.org/10.7554/elife.40981
https://doi.org/10.7554/elife.40981
Autor:
Tzu-Ling Tseng, Michael M. Cox, John R. Battista, Joseph R. Piechura, Hsin-Fang Hsu, Sindhu Chitteni-Pattu, Rose T. Byrne, Tricia A. Windgassen, Hung-Wen Li
Publikováno v:
DNA Repair. 26:30-43
Among strains of Escherichia coli that have evolved to survive extreme exposure to ionizing radiation, mutations in the recA gene are prominent and contribute substantially to the acquired phenotype. Changes at amino acid residue 276, D276A and D276N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b74329584a1cfb12f8f0ae8d17f16d1a
https://doi.org/10.1016/j.dnarep.2014.12.001
https://doi.org/10.1016/j.dnarep.2014.12.001
Publikováno v:
Nucleic Acids Research
Multi-protein DNA replication complexes called replisomes perform the essential process of copying cellular genetic information prior to cell division. Under ideal conditions, replisomes dissociate only after the entire genome has been duplicated. Ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bfdd5e72f236428908fff4ca25edc76
https://pubmed.ncbi.nlm.nih.gov/29202195
https://pubmed.ncbi.nlm.nih.gov/29202195
Publikováno v:
Molecular Cell. 50:882-893
Summary Transcriptional pausing, which regulates transcript elongation in both prokaryotes and eukaryotes, is thought to involve formation of alternative RNA polymerase conformations in which nucleotide addition is inhibited in part by restriction of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5ed01ee59c309bf29e087a5bb84c773
https://doi.org/10.1016/j.molcel.2013.05.015
https://doi.org/10.1016/j.molcel.2013.05.015
Autor:
Rachel A. Mooney, Jinwei Zhang, Dhananjaya Nayak, Robert Landick, Tricia A. Windgassen, Murali Palangat
Publikováno v:
Nucleic Acids Research
The conformational dynamics of the polymorphous trigger loop (TL) in RNA polymerase (RNAP) underlie multiple steps in the nucleotide addition cycle and diverse regulatory mechanisms. These mechanisms include nascent RNA hairpin-stabilized pausing, wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31f4493306d1c0fd5f06f1140e6b4139
https://pubmed.ncbi.nlm.nih.gov/25336618
https://pubmed.ncbi.nlm.nih.gov/25336618