Zobrazeno 1 - 10
of 304
pro vyhledávání: '"Tricellulin"'
Autor:
Chuican Huang, Zhenning Huang, Ping Wang, Xijing Wu, Qiaomiao Zhou, Jun Ding, Qing Luo, Weijia Wu, Xialin Fan, Lichun Fan
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
The MARVELD2 gene is located on chromosome 5q13.2 and is associated with autosomal recessive nonsyndromic hearing loss (OMIM: # 610572). In this study, we identified and reported a novel nonsense mutation in MARVELD2 c. 663G > A in a Chinese family.
Externí odkaz:
https://doaj.org/article/ca6462462cd84cffa30d1e45e1302908
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 12, Iss 8, Pp n/a-n/a (2024)
Abstract Background Hereditary hearing loss is an important component of congenital hearing loss. MARVELD2 (OMIM ID:610572), located in the DFNB49 locus, which encodes a tight junction protein tricellulin playing an important role in the sensory epit
Externí odkaz:
https://doaj.org/article/5d1e7e4961c349cb86522a08bf487660
Akademický článek
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Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
The oleoresin myrrh has been used for centuries as an anti-inflammatory remedy for a variety of diseases and is said to have a protective effect on the intestinal epithelium. An intact epithelial barrier function is the prerequisite for a healthy gut
Externí odkaz:
https://doaj.org/article/c1551ed713084d9eb5896e7ea39a868d
Autor:
Höfling, Corinna, Roßner, Steffen, Flachmeyer, Bianca, Krueger, Martin, Härtig, Wolfgang, Michalski, Dominik
Along with initiatives to understand the pathophysiology of stroke in detail and to identify neuroprotective targets, cell-stabilizing elements have gained increasing attention. Although cell culture experiments have indicated that tricellulin, α-ca
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A93506
https://ul.qucosa.de/api/qucosa%3A93506/attachment/ATT-0/
https://ul.qucosa.de/api/qucosa%3A93506/attachment/ATT-0/
Autor:
Karem Awad, Christian Barmeyer, Christian Bojarski, Oliver Nagel, In-Fah M. Lee, Michal R. Schweiger, Jörg-Dieter Schulzke, Roland Bücker
Publikováno v:
Cells, Vol 12, Iss 24, p 2846 (2023)
Background: In patients with diarrhea-predominant irritable bowel syndrome (IBS-D), the diarrheal mechanisms are largely unknown, and they were examined in this study on colon biopsies. Methods: Electrophysiological measurements were used for monitor
Externí odkaz:
https://doaj.org/article/617ff395507043f5b1568681be88f5b2
Autor:
Martina Schneemann, Lucas Heils, Verena Moos, Franziska Weiß, Susanne M. Krug, January Weiner, Dieter Beule, Ralf Gerhard, Jörg-Dieter Schulzke, Roland Bücker
Publikováno v:
Toxins, Vol 15, Iss 11, p 643 (2023)
Background: Clostridioides difficile toxins TcdA and TcdB are responsible for diarrhea and colitis. Lack of functional studies in organoid models of the gut prompted us to elucidate the toxin’s effects on epithelial barrier function and the molecul
Externí odkaz:
https://doaj.org/article/7f3885d1b10448c8ab6e17773d112dc2
Akademický článek
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Autor:
Jia-Chen E. Hu, Franziska Weiß, Christian Bojarski, Federica Branchi, Jörg-Dieter Schulzke, Michael Fromm, Susanne M. Krug
Publikováno v:
BMC Gastroenterology, Vol 21, Iss 1, Pp 1-11 (2021)
Abstract Background Ulcerative colitis (UC) has a relapsing and remitting pattern, wherein the underlying mechanisms of the relapse might involve an enhanced uptake of luminal antigens which stimulate the immune response. The tricellular tight juncti
Externí odkaz:
https://doaj.org/article/34df0e68687349aea2f0d276e6d12885
Publikováno v:
Particle and Fibre Toxicology, Vol 17, Iss 1, Pp 1-13 (2020)
Abstract Background While exposure to diesel exhaust particles has been linked to aberrant immune responses in allergic diseases such as asthma, little attention has been paid to their effects on the airway epithelial barrier. In this study, we sough
Externí odkaz:
https://doaj.org/article/80ca57ac592444c7918a50fa0129a1d4