Zobrazeno 1 - 10
of 541
pro vyhledávání: '"Triazolopyrimidine"'
Publikováno v:
Heliyon, Vol 10, Iss 5, Pp e26735- (2024)
Recently, heterocyclic compounds such as pyrido [2,3-d] pyrimidinones, 1,2,4-triazolopyrimidines, pyrimidoquinazolines, and quinoline derivatives have gained attention from researchers due to their pharmacological and biological activities. To synthe
Externí odkaz:
https://doaj.org/article/258a1b43074748e8983f2d3735674629
Autor:
Sherif S. Ragab, Noha E. Ibrahim, Mohamed S. Abdel-Aziz, Ahmed A. Elrashedy, Abdou K. Allayeh
Publikováno v:
Results in Chemistry, Vol 6, Iss , Pp 101163- (2023)
New series of triazolopyrimidine derivatives were designed, synthesized and fully characterized by spectroscopic tools. The new compounds were investigated as antimicrobial agents against two bacterial and two fungal strains. The antimicrobial result
Externí odkaz:
https://doaj.org/article/4c9b19557dc348ad98bc0748a06d0522
Akademický článek
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Publikováno v:
شیمی کاربردی روز, Vol 17, Iss 64, Pp 189-204 (2022)
Azolo-annulated pyrimidines have attracted continuing interest due primarily to their structural similarity to heterocyclic bases of DNA and RNA. As a consequence, these compounds can act as antimetabolites, being effective biologically active compou
Externí odkaz:
https://doaj.org/article/05fd00a48a83459eae50dca2cefb428b
Publikováno v:
Molecules, Vol 28, Iss 24, p 7997 (2023)
Inhibition of the Embryonic Ectoderm Development (EED) subunit in Polycomb Repressive Complex 2 (PRC2) can inhibit tumor growth. In this paper, we selected six experimentally designed EED competitive Inhibitors of the triazolopyrimidine derivatives c
Externí odkaz:
https://doaj.org/article/34d925d46349435fb3e34448268b4674
Publikováno v:
Future Journal of Pharmaceutical Sciences, Vol 7, Iss 1, Pp 1-10 (2021)
Abstract Background The sixteen (16) designed data set of substituted aryl amine-based triazolopyrimidine were docked against Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH) employing Molegro Virtual Docker (MVD) software and their pharm
Externí odkaz:
https://doaj.org/article/822be25d6f7747e8bedeeb4ff22f50c5
Autor:
Manel Ben Hassen, Dhouha Msalbi, Badr Jismy, Fares Elghali, Sami Aifa, Hassan Allouchi, Mohamed Abarbri, Fakher Chabchoub
Publikováno v:
Molecules, Vol 28, Iss 9, p 3917 (2023)
A series of new [1,2,4]triazolo[4,3-a]pyrimidine derivatives was prepared using a one-pot three-component synthesis from 5-amino-1-phenyl-1H-1,2,4-triazoles, aromatic aldehydes and ethyl acetoacetate. The compound structures were confirmed by IR, 1H-
Externí odkaz:
https://doaj.org/article/b697ac12475a4749a87b29d4cf13a855
Publikováno v:
Journal of Materials Research and Technology, Vol 9, Iss 3, Pp 6568-6578 (2020)
A new triazolopyrimidine derivative, namely, 6-hydroxy-7-phenyl-6,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidin-5(4H)-one (HPTP) was synthesized. Its corrosion inhibition performance on mild steel in 1 M HCl solution was researched through weight loss, p
Externí odkaz:
https://doaj.org/article/34ed5db0ce3143819e385d9a9ca31803
Autor:
Hatem A. Abuelizz, Nor Azman N. I. Iwana, Rohaya Ahmad, El-Hassane Anouar, Mohamed Marzouk, Rashad Al-Salahi
Publikováno v:
BMC Chemistry, Vol 13, Iss 1, Pp 1-14 (2019)
Abstract Diabetes is an emerging metabolic disorder. α-Glucosidase inhibitors, such as acarbose, delay the hydrolysis of carbohydrates by interfering with the digestive enzymes. This action decreases the glucose absorption and the postprandial gluco
Externí odkaz:
https://doaj.org/article/637eca829d9b45768e8a6d4a7065afc0
Akademický článek
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