Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Triazoles/pharmacology"'
Autor:
Darin Hassan, Rikesh Masania, Malcolm Richardson, Caroline B. Moore, Lilyann Novak-Frazer, David W. Denning, Samuel P Anees-Hill, Riina Rautemaa-Richardson
Publikováno v:
Novak-Frazer, L, Anees-Hill, S P, Hassan, D, Masania, R, Moore, C B, Richardson, M D, Denning, D W & Rautemaa-Richardson, R 2020, ' Deciphering Aspergillus fumigatus cyp51A-mediated triazole resistance by pyrosequencing of respiratory specimens ', Journal of Antimicrobial Chemotherapy, vol. 75, no. 12, pp. 3501-3509 . https://doi.org/10.1093/jac/dkaa357
Journal of Antimicrobial Chemotherapy
Journal of Antimicrobial Chemotherapy
Background Infections caused by triazole drug-resistant Aspergillus fumigatus are an increasing problem. The sensitivity of standard culture is poor, abrogating susceptibility testing. Early detection of resistance can improve patient outcomes, yet t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b8f8e246b6bf84fef3aeec86e5be816
https://www.research.manchester.ac.uk/portal/en/publications/deciphering-aspergillus-fumigatus-cyp51amediated-triazole-resistance-by-pyrosequencing-of-respiratory-specimens(898246bf-b520-4b34-b344-28f6f2e83832).html
https://www.research.manchester.ac.uk/portal/en/publications/deciphering-aspergillus-fumigatus-cyp51amediated-triazole-resistance-by-pyrosequencing-of-respiratory-specimens(898246bf-b520-4b34-b344-28f6f2e83832).html
Autor:
Handoko, L., Kaczkowski, B., Hon, C. C., Lizio, M., Wakamori, M., Matsuda, T., Ito, T., Jeyamohan, P., Sato, Y., Sakamoto, K., Yokoyama, S., Kimura, Hiroshi, Minoda, A., Umehara, T.
Publikováno v:
Epigenetics. 13(No. 4):410-431
The bromodomain and extra-terminal domain (BET) proteins are promising drug targets for cancer and immune diseases. However, BET inhibition effects have been studied more in the context of bromodomain-containing protein 4 (BRD4) than BRD2, and the BE
Autor:
Ruairi J. Fahy, Larry Bacon, Eimear Ann Joyce, Jacques F. Meis, Brian O'Connell, Thomas R. Rogers, Alida Fe Talento, Katie Dunne, Elisabeth Vandenberge, Grace Chan, Ferry Hagen, Niamh Murphy
Publikováno v:
Mycoses, 61, 570-575
Mycoses, 61, 8, pp. 570-575
Mycoses, 61(8), 570-575. John Wiley and Sons Ltd
Mycoses, 61, 8, pp. 570-575
Mycoses, 61(8), 570-575. John Wiley and Sons Ltd
Item does not contain fulltext Influenza virus infection is now recognised as a risk factor for invasive pulmonary aspergillosis (IPA). Delays in diagnosis contribute to delayed commencement of antifungal therapy. In addition, the emergence of resist
Autor:
Hicham Chahtane, Thanise Nogueira Füller, Pierre-Marie Allard, Laurence Marcourt, Emerson Ferreira Queiroz, Venkatasalam Shanmugabalaji, Jacques Falquet, Jean-Luc Wolfender, Luis Lopez-Molina
Publikováno v:
eLife, Vol. 7 (2018)
eLife
eLife, Vol 7 (2018)
eLife
eLife, Vol 7 (2018)
To anticipate potential seedling damage, plants block seed germination under unfavorable conditions. Previous studies investigated how seed germination is controlled in response to abiotic stresses through gibberellic and abscisic acid signaling. How
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::60a5539e85c61b0281a2fe63f717892f
https://archive-ouverte.unige.ch/unige:136483
https://archive-ouverte.unige.ch/unige:136483
Autor:
Dominique Sanglard, Eric Delarze
Publikováno v:
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy
Drug Resistance Updates : Reviews and Commentaries In Antimicrobial and Anticancer Chemotherapy, vol. 23, pp. 12-19
Drug Resistance Updates : Reviews and Commentaries In Antimicrobial and Anticancer Chemotherapy, vol. 23, pp. 12-19
A restricted number of antifungal agents are available for the therapy of fungal diseases. With the introduction of epidemiological cut-off values for each agent in important fungal pathogens based on the distribution of minimal inhibitory concentrat
Autor:
Gustavo José Cota de Freitas, Marliete Carvalho Costa, Guilhem Janbon, Lorena Vívien Neves de Oliveira, Frédérique Moyrand, Gabriella Freitas Ferreira, Hellem Cristina Silva Carneiro, Thais Furtado Ferreira Magalhães, Rafael Wesley Bastos, Karen Maia Rocha, Vanessa S. D. Carvalho, Cláudia Emanuela Viana Rocha, Tatiane Alves de Paixão, Daniel Assis Santos
Publikováno v:
Antimicrobial Agents and Chemotherapy
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2018, 62 (1), pp.e01179-17. ⟨10.1128/AAC.01179-17⟩
Antimicrobial Agents and Chemotherapy, 2018, 62 (1), pp.e01179-17. ⟨10.1128/AAC.01179-17⟩
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2018, 62 (1), pp.e01179-17. ⟨10.1128/AAC.01179-17⟩
Antimicrobial Agents and Chemotherapy, 2018, 62 (1), pp.e01179-17. ⟨10.1128/AAC.01179-17⟩
Cryptococcus gattii and Cryptococcus neoformans are environmental fungi that cause cryptococcosis, which is usually treated with amphotericin B and fluconazole. However, therapeutic failure is increasing because of the emergence of resistant strains.
Publikováno v:
Critical care (London, England), vol. 20, no. 1, pp. 125
Invasive fungal infections, particularly those caused by Candida species, are not uncommon in critically ill patients and are associated with considerable morbidity and mortality. Diagnosis and management of these infections can be challenging. In th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1900::11c0e14e1c9f9c51b9c97257de3719cf
https://serval.unil.ch/resource/serval:BIB_6E6DAB4E22B3.P001/REF.pdf
https://serval.unil.ch/resource/serval:BIB_6E6DAB4E22B3.P001/REF.pdf
Autor:
Delphine Effroy-Cuzzi, Julien Sechet, Anne Frey, Delphine Charif, Grégory Mouille, François Perreau, Adeline Berger, Helen M. North, Loïc Rajjou, Gwendal Cueff, Annie Marion-Poll
Publikováno v:
Plant Physiology
Plant Physiology, American Society of Plant Biologists, 2016, 170 (3), pp.1367--80. ⟨10.1104/pp.15.01312⟩
Plant Physiology, American Society of Plant Biologists, 2016, 170, pp.1367--80. ⟨10.1104/pp.15.01312⟩
Plant Physiology 3 (170), 1367-1380. (2016)
Plant Physiology, American Society of Plant Biologists, 2016, 170 (3), pp.1367--80. ⟨10.1104/pp.15.01312⟩
Plant Physiology, American Society of Plant Biologists, 2016, 170, pp.1367--80. ⟨10.1104/pp.15.01312⟩
Plant Physiology 3 (170), 1367-1380. (2016)
International audience; Cell wall remodeling is an essential mechanism for the regulation of plant growth and architecture, and xyloglucans (XyGs), the major hemicellulose, are often considered as spacers of cellulose microfibrils during growth. In t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7008e2c2ee971aff50812d098aa82cfe
https://hal-agroparistech.archives-ouvertes.fr/hal-01563909/document
https://hal-agroparistech.archives-ouvertes.fr/hal-01563909/document
Autor:
Cheila Rocha, Fernando Maltez, Umbelina Caixas, Pedro Borrego, Manuela Doroana, Patrícia Cavaco-Silva, Rita Calado, Inês Bártolo, Francisco Antunes, Helena Barroso, José Maria Marcelino, Nuno Taveira
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Agência para a Sociedade do Conhecimento (UMIC)-FCT-Sociedade da Informação
instacron:RCAAP
Agência para a Sociedade do Conhecimento (UMIC)-FCT-Sociedade da Informação
instacron:RCAAP
Background The baseline susceptibility of primary HIV-2 to maraviroc (MVC) and other entry inhibitors is currently unknown. Methods The susceptibility of 19 HIV-2 isolates obtained from asymptomatic and AIDS patients and seven HIV-1 clinical isolates
Autor:
Maria Simitsopoulou, Emmanuel Roilides, A. Orfanou, J. Ioannidis, C. Likartsis, Fotini Paliogianni, Thomas J. Walsh
Publikováno v:
Antimicrobial Agents and Chemotherapy. 51:1048-1054
We assessed the effect of voriconazole (VRC) on the expression and release of selected cytokines and chemokines in the THP-1 human monocytic cell line in response toAspergillus fumigatushyphal fragments (HF) by cDNA microarray analysis, reverse trans