Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Triantafyllos Zacharias"'
Autor:
Martin W. Berchtold, Lasse G. Lorentzen, Isabel Porth, Martin R. Larsen, Katarzyna Kulej, Jonas M. la Cour, Triantafyllos Zacharias, S. B. Panina, Mads Munk
Publikováno v:
Berchtold, M W, Munk, M, Kulej, K, Porth, I, Lorentzen, L, Panina, S, Zacharias, T, Larsen, M R & la Cour, J M 2021, ' The heart arrhythmia-linked D130G calmodulin mutation causes premature inhibitory autophosphorylation of CaMKII ', Biochimica et Biophysica Acta-Molecular Cell Research, vol. 1868, no. 12, 119119 . https://doi.org/10.1016/j.bbamcr.2021.119119
The Ca2+/calmodulin (CaM)-dependent kinase II (CaMKII) is well known for transmitting Ca2+-signals, which leads to a multitude of physiological responses. Its functionality is believed to involve CaMKII holoenzyme dynamics where trans-autophosphoryla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba4c11f32b74307e79a3b5846cbf5257
https://doi.org/10.1016/j.bbamcr.2021.119119
https://doi.org/10.1016/j.bbamcr.2021.119119
Autor:
Triantafyllos Zacharias, Michael J. Davies, Konstantina Flouda, Bente Gammelgaard, Thomas A. Jepps, Carl H. Schiesser
Publikováno v:
Biochemical pharmacology. 173
Chronic low-grade inflammation and oxidative damage are strongly associated with pathologies including cardiovascular disease. As a consequence, there is considerable interest in agents that mitigate damage. Selenium compounds can act as potent prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d1a6bca679a4e364cbdc8c4647cf328
https://pubmed.ncbi.nlm.nih.gov/31494145
https://pubmed.ncbi.nlm.nih.gov/31494145
Autor:
Triantafyllos Zacharias, Ioanna-Katerina Aggeli, Georgia Papapavlou, Isidoros Beis, Catherine Gaitanaki
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 91:1095-1106
“Calcium paradox” as a term describes the deleterious effects conferred to a heart perfused with a calcium-free solution followed by repletion, including loss of mechanical activity and sarcomere disruption. Given that the signaling mechanisms tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90991c5df85d46f0e7739acc2f2801ba
https://doi.org/10.1139/cjpp-2013-0081
https://doi.org/10.1139/cjpp-2013-0081
Autor:
Thomas Jespersen, Jau-Nian Chen, Katarzyna Kulej, Raffaela Torggler, Martin R. Larsen, Jonas M. la Cour, Triantafyllos Zacharias, Kevin Wang, Martin W. Berchtold
Publikováno v:
Berchtold, M W, Zacharias, T, Kulej, K, Wang, K, Torggler, R, Jespersen, T, Chen, J-N, Larsen, M R & la Cour, J M 2016, ' The arrhythmogenic calmodulin mutation D129G dysregulates cell growth, calmodulin-dependent kinase II activity, and cardiac function in zebrafish ', Journal of Biological Chemistry, vol. 291, no. 52, pp. 26636-26646 . https://doi.org/10.1074/jbc.M116.758680
The Journal of biological chemistry, vol 291, iss 52
The Journal of biological chemistry, vol 291, iss 52
Calmodulin (CaM) is a Ca(2+) binding protein modulating multiple targets, several of which are associated with cardiac pathophysiology. Recently, CaM mutations were linked to heart arrhythmia. CaM is crucial for cell growth and viability, yet the eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4450c2b0ac980a35a6b31621121d1a37
https://pubmed.ncbi.nlm.nih.gov/27815504
https://pubmed.ncbi.nlm.nih.gov/27815504