Zobrazeno 1 - 10
of 338
pro vyhledávání: '"Triantafilou, P"'
Autor:
Evgeniia Lobanova, Yu P. Zhang, Derya Emin, Jack Brelstaff, Lakmini Kahanawita, Maura Malpetti, Annelies Quaegebeur, Kathy Triantafilou, Martha Triantafilou, Henrik Zetterberg, James B. Rowe, Caroline H. Williams-Gray, Clare Elizabeth Bryant, David Klenerman
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Immunotherapeutic strategies for Alzheimer’s and Parkinson’s disease would be facilitated by better measures of inflammation. Here we established an ultra-sensitive single-molecule pull-down immunoassay combined with direct stochastic op
Externí odkaz:
https://doaj.org/article/3b89562d5e954dab9038f1d373df047b
Autor:
Kathy Triantafilou, Barbara Szomolay, Mark William Shepherd, Joshi Ramanjulu, Martha Triantafilou
Publikováno v:
Viruses, Vol 16, Iss 10, p 1541 (2024)
Some respiratory viruses, such as Human Rhinovirus, SARS-CoV-2, and Enterovirus D-68 (EV-D68), share the feature of hijacking host lipids in order to generate specialised replication organelles (ROs) with unique lipid compositions to enable viral rep
Externí odkaz:
https://doaj.org/article/7039d9d505154e7d85746a10018003ee
Akademický článek
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Autor:
Martha Triantafilou, Joshi Ramanjulu, Lee M. Booty, Gisela Jimenez-Duran, Hakan Keles, Ken Saunders, Neysa Nevins, Emma Koppe, Louise K. Modis, G. Scott Pesiridis, John Bertin, Kathy Triantafilou
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Evidence exists that the typically antiviral signaling mediator STING is, counterintuitively, needed for optimal human rhinovirus infection. Here the authors confirm this finding and show how human rhinovirus can reduce stored Ca2+ levels to drive th
Externí odkaz:
https://doaj.org/article/59654decd629466e86c28da34c89bb64
Alzheimer's disease (AD) is a neurodegenerative disorder and the most common cause of dementia in the elderly. The extracellular accumulation of amyloid-$\beta$ (A$\beta$) in senile plaques is a principal event in the pathogenesis and there is growin
Externí odkaz:
http://arxiv.org/abs/1803.01201
Autor:
Oliver Wright, Anna Harris, Van Dien Nguyen, You Zhou, Maxim Durand, Abbie Jayyaratnam, Darren Gormley, Luke A. J. O’Neill, Kathy Triantafilou, Eva Maria Nichols, Lee M. Booty
Publikováno v:
Cells, Vol 12, Iss 23, p 2707 (2023)
The complement system mediates diverse regulatory immunological functions. C5aR2, an enigmatic receptor for anaphylatoxin C5a, has been shown to modulate PRR-dependent pro-inflammatory cytokine secretion in human macrophages. However, the specific do
Externí odkaz:
https://doaj.org/article/aea08597c712489e973143c9958d8a70
Autor:
Gisela Jimenez-Duran, Joseph Kozole, Rachel Peltier-Heap, Eleanor R. Dickinson, Christopher R. Kwiatkowski, Francesca Zappacosta, Roland S. Annan, Nicholas W. Galwey, Eva-Maria Nichols, Louise K. Modis, Martha Triantafilou, Kathy Triantafilou, Lee M. Booty
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The complement system is an ancient and critical part of innate immunity. Recent studies have highlighted novel roles of complement beyond lysis of invading pathogens with implications in regulating the innate immune response, as well as contributing
Externí odkaz:
https://doaj.org/article/18224861a8b0475c8ebbec8ed8c12015
Akademický článek
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Autor:
Kathy Triantafilou, Christopher J K Ward, Magdalena Czubala, Robert G Ferris, Emma Koppe, Curt Haffner, Vincent Piguet, Vipulkumar K Patel, Heather Amrine-Madsen, Louise K Modis, Seth L Masters, Martha Triantafilou
Publikováno v:
PLoS Pathogens, Vol 17, Iss 4, p e1009417 (2021)
Macrophages are important drivers of pathogenesis and progression to AIDS in HIV infection. The virus in the later phases of the infection is often predominantly macrophage-tropic and this tropism contributes to a chronic inflammatory and immune acti
Externí odkaz:
https://doaj.org/article/537924792012487eb14fefc52c9d380b
Akademický článek
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