Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Triana Espinosa-Jiménez"'
Autor:
Triana Espinosa-Jiménez, Amanda Cano, Elena Sánchez-López, Jordi Olloquequi, Jaume Folch, Mònica Bulló, Ester Verdaguer, Carme Auladell, Caterina Pont, Diego Muñoz-Torrero, Antoni Parcerisas, Antoni Camins, Miren Ettcheto
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-18 (2023)
Abstract Background Alzheimer’s disease (AD) is characterized by a polyetiological origin. Despite the global burden of AD and the advances made in AD drug research and development, the cure of the disease remains elusive, since any developed drug
Externí odkaz:
https://doaj.org/article/14a2e34bc2894fbd8edf2bc0de8aa485
Autor:
Oriol Busquets, Triana Espinosa-Jiménez, Miren Ettcheto, Jordi Olloquequi, Mònica Bulló, Eva Carro, José Luis Cantero, Gemma Casadesús, Jaume Folch, Ester Verdaguer, Carme Auladell, Antoni Camins
Publikováno v:
Molecular Medicine, Vol 28, Iss 1, Pp 1-15 (2022)
Abstract Background and aim The appearance of alterations in normal metabolic activity has been increasingly considered a risk factor for the development of sporadic and late-onset neurodegenerative diseases. In this report, we induced chronic metabo
Externí odkaz:
https://doaj.org/article/87b4933c55b04c7bb1bdf8cc181e31d4
Autor:
Triana Espinosa-Jiménez, Oriol Busquets, Amanda Cano, Elena Sánchez-López, Ester Verdaguer, Antoni Parcerisas, Jordi Olloquequi, Carme Auladell, Jaume Folch, Walter Wahli, Manuel Vázquez-Carrera, Antoni Camins, Miren Ettcheto
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Peroxisome proliferator-activated receptor β/δ (PPARβ/δ), the most PPAR abundant isotype in the central nervous system, is involved in microglial homeostasis and metabolism, whose disturbances have been demonstrated to play a key role in memory i
Externí odkaz:
https://doaj.org/article/2721f1f916e94f66905ee7d3a6d12953
Autor:
Jaume Folch, Jordi Olloquequi, Miren Ettcheto, Oriol Busquets, Elena Sánchez-López, Amanda Cano, Triana Espinosa-Jiménez, Maria Luisa García, Carlos Beas-Zarate, Gemma Casadesús, Mónica Bulló, Carme Auladell, Antoni Camins
Publikováno v:
Frontiers in Aging Neuroscience, Vol 11 (2019)
Nowadays, Alzheimer’s disease (AD) is a severe sociological and clinical problem. Since it was first described, there has been a constant increase in its incidence and, for now, there are no effective treatments since current approved medications h
Externí odkaz:
https://doaj.org/article/2ad8c9807411458fbe1c64ecafeed795
Autor:
Triana Espinosa-Jiménez, Marina Carrasco, Katherine Herrera, Ester Verdaguer, Antoni Camins, Miren Ettcheto, Jaume Folch, Patricia Regina Manzine, Carme Auladell, Jordi Olloquequi, Oriol Busquets, Elena Sánchez-López, Amanda Cano
Publikováno v:
Cell & Bioscience, Vol 11, Iss 1, Pp 1-17 (2021)
Cell & Bioscience
Cell & Bioscience
Background Several studies stablished a relationship between metabolic disturbances and Alzheimer´s disease (AD) where inflammation plays a pivotal role. However, mechanisms involved still remain unclear. In the present study, we aimed to evaluate c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c009e1a067c4829c93738938913ca9de
https://doaj.org/article/9772ed61c6b242819b97c186ae7619e3
https://doaj.org/article/9772ed61c6b242819b97c186ae7619e3
Autor:
Jordi Olloquequi, Rubén Darío Castro-Torres, Gemma Casadesus, Jaume Folch, Miren Ettcheto, Oriol Busquets, Elena Sánchez-López, Carme Auladell, Amanda Cano, Patricia Regina Manzine, Antoni Camins, Francesc X. Sureda, Triana Espinosa-Jiménez, Ester Verdaguer
Publikováno v:
J Alzheimers Dis
To deeply understand late onset Alzheimer’s disease (LOAD), it may be necessary to change the concept that it is a disease exclusively driven by aging processes. The onset of LOAD could be associated with a previous peripheral stress at the level o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04f53752d5095f87b8580141d55ac7bc
https://doi.org/10.3233/jad-201106
https://doi.org/10.3233/jad-201106
Autor:
Gemma Casadesus, Oriol Busquets, Ester Verdaguer, Rubén Darío Castro-Torres, Àuria Eritja, Miren Ettcheto, Carme Auladell, Jordi Olloquequi, Antoni Camins, Jaume Folch, Carlos Beas-Zarate, Mònica Bulló, Triana Espinosa-Jiménez
Publikováno v:
Journal of Molecular Medicine. 97:1723-1733
The development of metabolic alterations like insulin resistance has been associated with dysfunctions in mitochondrial oxidative capacity, induction of neuroinflammatory responses, and the appearance of cognitive impairments in the brain. The c-Jun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d74239fc99e83d89416b9f922afdf791
https://doi.org/10.1007/s00109-019-01856-z
https://doi.org/10.1007/s00109-019-01856-z
Autor:
Ester Verdaguer, Esther Rodríguez-Gallego, Carme Auladell, Marina Carrasco, Mònica Bulló, Montserrat Pinent, Jaume Folch, Miren Ettcheto, Antoni Camins, Oriol Busquets, Triana Espinosa-Jiménez
Publikováno v:
Nutritional neuroscience. 25(12)
Deregulations like the loss of sensitivity to insulin (insulin resistance) and chronic inflammation are alterations very commonly found in sporadic forms of neurodegenerative pathologies. Thus, finding strategies to protect against them, may lead to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2f52fcc08701d3322377c0564dc679b
https://pubmed.ncbi.nlm.nih.gov/34789070
https://pubmed.ncbi.nlm.nih.gov/34789070
Autor:
Triana Espinosa-Jiménez, Carme Auladell, Ester Verdaguer, Walter Wahli, Jordi Olloquequi, Jaume Folch, Oriol Busquets, Manel Vazquez-Carrera, Amanda Cano, Miren Ettcheto, Antoni Camins
BackgroundPPARβ/δ, the most PPAR abundant isotype in the central nervous system is involved in the modulation of microglial homeostasis and metabolism. Several studies have demonstrated that people suffering from type 2 diabetes mellitus develop co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc373d9cdf4d3372ba21e13287a600ca
https://doi.org/10.21203/rs.3.rs-895676/v1
https://doi.org/10.21203/rs.3.rs-895676/v1
A Chronological Review of Potential Disease-Modifying Therapeutic Strategies for Alzheimer's Disease
Autor:
Miren Ettcheto, Ester Verdaguer, Carme Auladell, Antoni Camins, Triana Espinosa-Jiménez, Oriol Busquets
Publikováno v:
Current pharmaceutical design. 26(12)
Late-onset Alzheimer’s disease (LOAD) is a neurodegenerative disorder that has become a worldwide health problem. This pathology has been classically characterized for its affectation on cognitive function and the presence of depositions of extrace
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::658842905d9bff24d405efb8ac3a4f1e
https://pubmed.ncbi.nlm.nih.gov/32066356
https://pubmed.ncbi.nlm.nih.gov/32066356