Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Trial discontinuation"'
Autor:
Dmitry Gryaznov, Ayodele Odutayo, Belinda von Niederhäusern, Benjamin Speich, Benjamin Kasenda, Elena Ojeda-Ruiz, Anette Blümle, Stefan Schandelmaier, Dominik Mertz, Yuki Tomonaga, Alain Amstutz, Christiane Pauli-Magnus, Viktoria Gloy, Karin Bischoff, Katharina Wollmann, Laura Rehner, Szimonetta Lohner, Joerg J. Meerpohl, Alain Nordmann, Katharina Klatte, Nilabh Ghosh, Ala Taji Heravi, Jacqueline Wong, Ngai Chow, Patrick Jiho Hong, Kimberly Mc Cord, Sirintip Sricharoenchai, Jason W. Busse, Arnav Agarwal, Ramon Saccilotto, Matthias Schwenkglenks, Giusi Moffa, Lars G. Hemkens, Sally Hopewell, Erik von Elm, Matthias Briel
Publikováno v:
Trials, Vol 21, Iss 1, Pp 1-13 (2020)
Abstract Background Clearly structured and comprehensive protocols are an essential component to ensure safety of participants, data validity, successful conduct, and credibility of results of randomized clinical trials (RCTs). Funding agencies, rese
Externí odkaz:
https://doaj.org/article/c74de565372d47f49657913f07545ea7
Publikováno v:
Brain and Spine, Vol 2, Iss , Pp 100922- (2022)
Introduction: The scale of waste in research funding systems is large and detrimental to research capacity. Both incompleteness and non-publication of Randomised Controlled Trials (RCTs) have been increasingly reported in the literature. This is a se
Externí odkaz:
https://doaj.org/article/a85e2f975b0c462a8a59c1808c82ef39
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Autor:
Ramy Sedhom, Mikkjal Skardhamar, Michael A. Carducci, Henk M.W. Verheul, Joeri A. J. Douma, Divya Dharmaraj, Anthony De Felice, Mariette Labots, Laurien M. Buffart, Esther Lee, Willemien C. Menke-van der Houven van Oordt, Nilofer S. Azad
Publikováno v:
Cancers
Volume 13
Issue 10
Cancers, 13, 10
Cancers, Vol 13, Iss 2304, p 2304 (2021)
Cancers, 13(10):2304. Multidisciplinary Digital Publishing Institute (MDPI)
Cancers, 13
Douma, J A J, Buffart, L M, Sedhom, R, Labots, M, Menke-van der Houven van Oordt, W C, Skardhamar, M, de Felice, A, Lee, E, Dharmaraj, D, Azad, N S, Carducci, M A & Verheul, H M W 2021, ' Clinical predictors of early trial discontinuation for patients participating in phase i clinical trials in oncology ', Cancers, vol. 13, no. 10, 2304 . https://doi.org/10.3390/cancers13102304
Volume 13
Issue 10
Cancers, 13, 10
Cancers, Vol 13, Iss 2304, p 2304 (2021)
Cancers, 13(10):2304. Multidisciplinary Digital Publishing Institute (MDPI)
Cancers, 13
Douma, J A J, Buffart, L M, Sedhom, R, Labots, M, Menke-van der Houven van Oordt, W C, Skardhamar, M, de Felice, A, Lee, E, Dharmaraj, D, Azad, N S, Carducci, M A & Verheul, H M W 2021, ' Clinical predictors of early trial discontinuation for patients participating in phase i clinical trials in oncology ', Cancers, vol. 13, no. 10, 2304 . https://doi.org/10.3390/cancers13102304
Despite stringent eligibility criteria for trial participation, early discontinuation often occurs in phase I trials. To better identify patients unlikely to benefit from phase I trials, we investigated predictors for early trial discontinuation. Dat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad006f8d0322367800dd40673e250f32
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Sirintip Sricharoenchai, Stefan Schandelmaier, Patrick Jiho Hong, Dmitry Gryaznov, Belinda von Niederhäusern, Matthias Briel, Katharina Wollmann, Christiane Pauli-Magnus, Erik von Elm, Dominik Mertz, Yuki Tomonaga, Ngai Chow, Lars G. Hemkens, Matthias Schwenkglenks, Sally Hopewell, Arnav Agarwal, Anette Blümle, Kimberly A. Mc Cord, Alain J Nordmann, Joerg J Meerpohl, Alain Amstutz, Elena Ojeda-Ruiz, Benjamin Kasenda, Ramon Saccilotto, Giusi Moffa, Nilabh Ghosh, Viktoria Gloy, Jacqueline Wong, Szimonetta Lohner, Benjamin Speich, Jason W. Busse, Katharina Klatte, Ala Taji Heravi, Ayodele Odutayo, Karin Bischoff, Laura Rehner
Publikováno v:
Trials
Trials, Vol 21, Iss 1, Pp 1-13 (2020)
Trials, Vol 21, Iss 1, Pp 1-13 (2020)
Background Clearly structured and comprehensive protocols are an essential component to ensure safety of participants, data validity, successful conduct, and credibility of results of randomized clinical trials (RCTs). Funding agencies, research ethi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f42e8a59e52dbd4395141e47b926ee5a
https://ora.ox.ac.uk/objects/uuid:4d517411-eba7-4950-868c-9767f9322e75
https://ora.ox.ac.uk/objects/uuid:4d517411-eba7-4950-868c-9767f9322e75
Autor:
Myra E. van Linde, Mieke Alberts, Laurien M. Buffart, Sonja Zweegman, Henk M.W. Verheul, Niels C. W. J. van de Donk, Sandy Kruyswijk, Joeri A J Douma
Publikováno v:
Supportive Care in Cancer
Supportive Care in Cancer, 29(7), 3783-3792. Springer Verlag
Supportive Care in Cancer, 29, 3783-3792
Douma, J A J, Zweegman, S, Alberts, M, Kruyswijk, S, van de Donk, N C W J, van Linde, M, Buffart, L M & Verheul, H M W 2021, ' Smartphone measurements of physical activity and fitness are associated with early trial discontinuation of patients in (hemato)oncology phase I/II clinical trials ', Supportive Care in Cancer, vol. 29, no. 7, pp. 3783-3792 . https://doi.org/10.1007/s00520-020-05902-2
Supportive Care in Cancer, 29, 7, pp. 3783-3792
Supportive Care in Cancer, 29(7), 3783-3792. Springer Verlag
Supportive Care in Cancer, 29, 3783-3792
Douma, J A J, Zweegman, S, Alberts, M, Kruyswijk, S, van de Donk, N C W J, van Linde, M, Buffart, L M & Verheul, H M W 2021, ' Smartphone measurements of physical activity and fitness are associated with early trial discontinuation of patients in (hemato)oncology phase I/II clinical trials ', Supportive Care in Cancer, vol. 29, no. 7, pp. 3783-3792 . https://doi.org/10.1007/s00520-020-05902-2
Supportive Care in Cancer, 29, 7, pp. 3783-3792
Background Patients, who discontinue early, do not benefit from phase I/II clinical trials (early-phase clinical trials (EPCT)). In this study, associations between objective smartphone measurements of physical activity and fitness and early trial di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c8ce7a19bd568d8e9d311895078d293
https://pubmed.ncbi.nlm.nih.gov/33236210
https://pubmed.ncbi.nlm.nih.gov/33236210
Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
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