Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Trey A Ronnebaum"'
Publikováno v:
Biochemistry. 61(18)
The regiospecific prenylation of an aromatic amino acid catalyzed by a dimethylallyl-l-tryptophan synthase (DMATS) is a key step in the biosynthesis of many fungal and bacterial natural products. DMATS enzymes share a common "ABBA" fold with divergen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::434209d989875d088aa5eff80ae535e9
https://pubmed.ncbi.nlm.nih.gov/36084241
https://pubmed.ncbi.nlm.nih.gov/36084241
Publikováno v:
Biochemistry. 61:2025-2035
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c028f26afdb625715a883e52bb2bb99
https://doi.org/10.1021/acs.biochem.2c00350
https://doi.org/10.1021/acs.biochem.2c00350
Autor:
Catherine L. Shelton, Kathleen M. Meneely, Trey A. Ronnebaum, Annemarie S. Chilton, Andrew P. Riley, Thomas E. Prisinzano, Audrey L. Lamb
Publikováno v:
JBIC Journal of Biological Inorganic Chemistry. 27:541-551
Pseudomonas aeruginosa is an increasingly antibiotic-resistant pathogen that causes severe lung infections, burn wound infections, and diabetic foot infections. P. aeruginosa produces the siderophore pyochelin through the use of a non-ribosomal pepti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdaadd794620d110796e63606568c941
https://doi.org/10.1007/s00775-022-01941-8
https://doi.org/10.1007/s00775-022-01941-8
Autor:
Alex A. Meier, Hee-Jung Moon, Sinan Sabuncu, Priya Singh, Trey A. Ronnebaum, Siyu Ou, Justin T. Douglas, Timothy A. Jackson, Pierre Moënne-Loccoz, Minae Mure
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 22; Pages: 13966
Lysyl oxidase-2 (LOXL2) is a Cu2+ and lysine tyrosylquinone (LTQ)-dependent amine oxidase that catalyzes the oxidative deamination of peptidyl lysine and hydroxylysine residues to promote crosslinking of extracellular matrix proteins. LTQ is post-tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76d3cd2e33f1af9a48237bff998eb5d5
Autor:
Alex A, Meier, Hee-Jung, Moon, Sinan, Sabuncu, Priya, Singh, Trey A, Ronnebaum, Siyu, Ou, Justin T, Douglas, Timothy A, Jackson, Pierre, Moënne-Loccoz, Minae, Mure
Publikováno v:
International journal of molecular sciences. 23(22)
Lysyl oxidase-2 (LOXL2) is a Cu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d8890dba88e37a3aaa7be4a9c88b8074
https://pubmed.ncbi.nlm.nih.gov/36430446
https://pubmed.ncbi.nlm.nih.gov/36430446
Publikováno v:
Biochemistry. 59:4744-4754
The sesquiterpene cyclase epi-isozizaene synthase (EIZS) catalyzes the cyclization of farnesyl diphosphate to form the tricyclic precursor of the antibiotic albaflavenone. The hydrophobic active site is largely defined by aromatic residues that direc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::751ceeb15dfe2c367625bfe37ccf9ab8
https://doi.org/10.1021/acs.biochem.0c00876
https://doi.org/10.1021/acs.biochem.0c00876
Autor:
Trey A. Ronnebaum, Samuel A. Eaton, Emily A. E. Brackhahn, Jacque L. Faylo, Kushol Gupta, David W. Christianson
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c2abdc9f7dd49fe42ee7b7c25d8b5ad
https://doi.org/10.1096/fasebj.2022.36.s1.l7991
https://doi.org/10.1096/fasebj.2022.36.s1.l7991
Publikováno v:
Acc Chem Res
ConspectusThe magnificent chemodiversity of more than 95 000 terpenoid natural products identified to date largely originates from catalysis by two types of terpene synthases, prenyltransferases and cyclases. Prenyltransferases utilize 5-carbon build
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e1794ecf6373dccaa5d515ae7812d3b
https://pubmed.ncbi.nlm.nih.gov/34254507
https://pubmed.ncbi.nlm.nih.gov/34254507
Autor:
Jeffrey S. McFarlane, Annemarie S. Chilton, Kathleen M. Meneely, Aron W. Fenton, Audrey L. Lamb, Trey A Ronnebaum
Publikováno v:
Acta Crystallogr F Struct Biol Commun
Human liver pyruvate kinase (hLPYK) converts phosphoenolpyruvate to pyruvate in the final step of glycolysis. hLPYK is allosterically activated by fructose-1,6-bisphosphate (Fru-1,6-BP). The allosteric site, as defined by previous structural studies,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69258059dea521201b804245b57b59f4
https://doi.org/10.1107/s2053230x19007209
https://doi.org/10.1107/s2053230x19007209
Autor:
Trey A Ronnebaum, Audrey L. Lamb, Thomas E. Prisinzano, Squire J. Booker, Jeffrey S. McFarlane
Publikováno v:
Biochemistry. 58:665-678
Nonribosomal peptide synthetases use tailoring domains to incorporate chemical diversity into the final natural product. A structurally unique set of tailoring domains are found to be stuffed within adenylation domains and have only recently begun to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c68d6594e744e20317f789f85202e563
https://doi.org/10.1021/acs.biochem.8b00716
https://doi.org/10.1021/acs.biochem.8b00716