Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Trevor R. Melkonian"'
Publikováno v:
Methods in Enzymology ISBN: 9780443152764
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6be59ee2b2b2db82fec64282c49332f8
https://doi.org/10.1016/bs.mie.2023.03.010
https://doi.org/10.1016/bs.mie.2023.03.010
Autor:
Nemanja Vuksanovic, Rajdeep S Virdi, Trevor R Melkonian, Robert Bavisotto, Nicholas Hopper, Nicholas R. Silvaggi, David N. Frick
Publikováno v:
Slas Discovery
bioRxiv
bioRxiv
The Mac1 domain of the multifunctional SARS-CoV-2 non-structural protein 3 (nsp3) is a potential COVID-19 drug target because it is suspected to enhance the ability of the virus to evade the human immune system. The SARS-CoV-2 Mac1 domain binds ADP-r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79149885fd5d4a061115aef8bb6f5866
http://europepmc.org/articles/PMC7684785
http://europepmc.org/articles/PMC7684785
Publikováno v:
Biochemistry. 58(52)
Human isocitrate dehydrogenase 1 (HsICDH1) is a cytoplasmic homodimeric Mg(II)-dependent enzyme that converts d-isocitrate (D-ICT) and NADP+ to α-ketoglutarate (AKG), CO2, and NADPH. The active sites are formed at the subunit interface and incorpora
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc4754db4097c5f3b2d3e9e40bc58641
https://pubmed.ncbi.nlm.nih.gov/32847354
https://pubmed.ncbi.nlm.nih.gov/32847354
Publikováno v:
Biochemistry. 59:3284-3284
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a222084cd37f9b0f23f50982c5f4c685
https://doi.org/10.1021/acs.biochem.0c00649
https://doi.org/10.1021/acs.biochem.0c00649
Autor:
Rajdeep S. Virdi, Bavisotto, Robert V., Hopper, Nicholas C., Vuksanovic, Nemanja, Melkonian, Trevor R., Silvaggi, Nicholas R., Frick, David N.
Supplemental material, Supplemental_Information for Discovery of Drug-Like Ligands for the Mac1 Domain of SARS-CoV-2 Nsp3 by Rajdeep S. Virdi, Robert V. Bavisotto, Nicholas C. Hopper, Nemanja Vuksanovic, Trevor R. Melkonian, Nicholas R. Silvaggi and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3dde3fc543318e2e829d2d7f5b02a3b
Autor:
John P. Richard, Graham Moran
New Experimental Probes for Enzyme Specificity and Mechanism, Volume 685, the latest release in the Methods of Enzymology series, highlights new advances in the field with this new volume presenting interesting chapters on a variety of topics includi