Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Trevor P Creamer"'
Autor:
Praveen R Juvvadi, Christopher Gehrke, Jarrod R Fortwendel, Frédéric Lamoth, Erik J Soderblom, Erik C Cook, Michael A Hast, Yohannes G Asfaw, M Arthur Moseley, Trevor P Creamer, William J Steinbach
Publikováno v:
PLoS Pathogens, Vol 9, Iss 8, p e1003564 (2013)
The fungus Aspergillus fumigatus is a leading infectious killer in immunocompromised patients. Calcineurin, a calmodulin (CaM)-dependent protein phosphatase comprised of calcineurin A (CnaA) and calcineurin B (CnaB) subunits, localizes at the hyphal
Externí odkaz:
https://doaj.org/article/847cf8464757453d8a5060dcb40287de
Autor:
Brian Stevenson, Henry A Choy, Marija Pinne, Matthew L Rotondi, M Clarke Miller, Edward Demoll, Peter Kraiczy, Anne E Cooley, Trevor P Creamer, Marc A Suchard, Catherine A Brissette, Ashutosh Verma, David A Haake
Publikováno v:
PLoS ONE, Vol 2, Iss 11, p e1188 (2007)
The pathogenic spirochete Leptospira interrogans disseminates throughout its hosts via the bloodstream, then invades and colonizes a variety of host tissues. Infectious leptospires are resistant to killing by their hosts' alternative pathway of compl
Externí odkaz:
https://doaj.org/article/cf75645695ac434ebc9eb6f2120bffb2
Autor:
Kerri Beth Boggs, Kearstin Edmonds, Nicolas Cifuentes-Munoz, Farah El Najjar, Conny Ossandón, McKenna Roe, Chao Wu, Carole L. Moncman, Trevor P. Creamer, Gaya K. Amarasinghe, Daisy W. Leung, Rebecca Ellis Dutch
Publikováno v:
mBio, Vol 13, Iss 3 (2022)
ABSTRACT Human metapneumovirus (HMPV) inclusion bodies (IBs) are dynamic structures required for efficient viral replication and transcription. The minimum components needed to form IB-like structures in cells are the nucleoprotein (N) and the tetram
Externí odkaz:
https://doaj.org/article/e5137f9be8254d0cb55904ed6c848d46
Autor:
Trevor P. Creamer
Publikováno v:
Cell Communication and Signaling, Vol 18, Iss 1, Pp 1-12 (2020)
Abstract The serine/threonine phosphatase calcineurin acts as a crucial connection between calcium signaling the phosphorylation states of numerous important substrates. These substrates include, but are not limited to, transcription factors, recepto
Externí odkaz:
https://doaj.org/article/95e2e1941fad4aeea9225b087936d7e5
Autor:
Trevor P. Creamer, Rebecca Ellis Dutch, F. El Najjar, Kerri Beth Boggs, Nicolás Cifuentes-Muñoz, Carole L. Moncman, M. Roe, Kearstin Edmonds, C. Ossandon
Human metapneumovirus (HMPV) inclusion bodies (IBs) are dynamic structures required for efficient viral replication and transcription. The minimum components needed to form IB-like structures in cells are the nucleoprotein (N) and the tetrameric phos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04c361d950c253ad690ebede95c21c90
https://doi.org/10.1101/2021.09.24.461765
https://doi.org/10.1101/2021.09.24.461765
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1862:2651-2659
Calcineurin (CaN) is a serine/threonine phosphatase that regulates a variety of physiological and pathophysiological processes in mammalian tissue. The calcineurin (CaN) regulatory domain (RD) is responsible for regulating the enzyme’s phosphatase
Autor:
Trevor P. Creamer, Erik C. Cook
Publikováno v:
ProteinsREFERENCES. 88(12)
Recent work has revealed that the association of a disordered region of a protein with a folded binding partner can occur as rapidly as association between two folded proteins. This is the case for the phosphatase calcineurin (CaN) and its associatio
Autor:
Erik C. Cook, Trevor P. Creamer, John Hunt, Dinesh K. Yadav, Sri Ramya Tata, Nicholas C. Fitzkee
Publikováno v:
Biomolecular NMR Assignments. 11:215-219
Calcineurin (CaN) plays an important role in T-cell activation, cardiac system development and nervous system function. Previous studies have demonstrated that the regulatory domain (RD) of CaN binds calmodulin (CaM) towards the N-terminal end. Calci
Autor:
Bin Sun, Darin Vaughan, Jonathan P. Davis, Peter M. Kekenes-Huskey, Trevor P. Creamer, Svetlana B. Tikunova
Publikováno v:
Biochemistry
Calcineurin (CaN) is a calcium-dependent phosphatase involved in numerous signaling pathways. Its activation is in part driven by the binding of calmodulin (CaM) to a CaM recognition region (CaMBR) within CaN's regulatory domain (RD). However, second
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5e57cb2a39620422afcdab7c7339d94
https://europepmc.org/articles/PMC7336278/
https://europepmc.org/articles/PMC7336278/
Autor:
Darin Vaughan, Jonathan P. Davis, Trevor P. Creamer, Peter M. Kekenes-Huskey, Bin Sun, Svetlana B. Tikunova
Calcineurin (CaN) is a calcium-dependent phosphatase involved in numerous signaling pathways. Its activation by Ca2+ is in part driven by binding of calmodulin (CaM) to a CaM-recognition motif within the phosphatase's regulatory domain (RD); however,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::655c22b69954076d19ee11f41208e1e9
https://doi.org/10.1101/665158
https://doi.org/10.1101/665158