Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Trevor McKee"'
Autor:
Jialing Tang, Nanyoung Yoon, Keith Dadson, Hye Kyoung Sung, Yubin Lei, Thanh Q. Dang, Wing Yan Chung, Saher Ahmed, Ali A. Abdul-Sater, Jun Wu, Ren-Ke Li, James Jonkman, Trevor McKee, Justin Grant, Jeffrey D. Peterson, Gary Sweeney
Publikováno v:
Autophagy Reports, Vol 3, Iss 1 (2024)
ABSTRACTMyocardial ischemia/reperfusion (I/R) injury is exacerbated in diabetic individuals and animal models. We tested whether autophagy is an important cellular determinant of cell death. First, we utilized a cellular model of hypoxia reoxygenatio
Externí odkaz:
https://doaj.org/article/b996ed38c7774fe3b10f431b9eea7419
Autor:
Marsel Lino, David Ngai, Alison Liu, Amanda Mohabeer, Cameron Harper, Laura-lee Caruso, Stephanie A. Schroer, Fred Fu, Trevor McKee, Adria Giacca, Minna Woo, Michelle P. Bendeck
Publikováno v:
Molecular Metabolism, Vol 39, Iss , Pp - (2020)
Objective: Discoidin domain receptor 1 (DDR1) is a collagen binding receptor tyrosine kinase implicated in atherosclerosis, fibrosis, and cancer. Our previous research showed that DDR1 could regulate smooth muscle cell trans-differentiation, fibrosis
Externí odkaz:
https://doaj.org/article/adaf86432ad34376b601b029bdeb846b
Autor:
Sanjana Chowdhury, Eric Yung, Melania Pintilie, Hala Muaddi, Selim Chaib, ManTek Yeung, Manlio Fusciello, Jenna Sykes, Bethany Pitcher, Anna Hagenkort, Trevor McKee, Ravi Vellanki, Eric Chen, Robert G Bristow, Bradly G Wouters, Marianne Koritzinsky
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0165214 (2016)
There is great interest in repurposing the commonly prescribed anti-diabetic drug metformin for cancer therapy. Intracellular uptake and retention of metformin is affected by the expression of organic cation transporters (OCT) 1-3 and by multidrug an
Externí odkaz:
https://doaj.org/article/655751f8b08940bbb463ec0183fbdf76
Autor:
Yves Boucher, Rakesh K. Jain, Lance L. Munn, Xiaoye Wang, Jean Yannis Perentes, Trevor McKee, Michael Awad, Zoe N. Demou
Supplementary Figure from Lack of Telopeptides in Fibrillar Collagen I Promotes the Invasion of a Metastatic Breast Tumor Cell Line
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20518a401e33836994f2131b9a775efe
https://doi.org/10.1158/0008-5472.22363896.v1
https://doi.org/10.1158/0008-5472.22363896.v1
Autor:
Yves Boucher, Rakesh K. Jain, Lance L. Munn, Xiaoye Wang, Jean Yannis Perentes, Trevor McKee, Michael Awad, Zoe N. Demou
Supplementary Movie 2 from Lack of Telopeptides in Fibrillar Collagen I Promotes the Invasion of a Metastatic Breast Tumor Cell Line
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88adddfd22a4c625924e30a6ef52d680
https://doi.org/10.1158/0008-5472.22363890
https://doi.org/10.1158/0008-5472.22363890
Autor:
Yves Boucher, Rakesh K. Jain, Lance L. Munn, Xiaoye Wang, Jean Yannis Perentes, Trevor McKee, Michael Awad, Zoe N. Demou
Supplementary Movie 1 from Lack of Telopeptides in Fibrillar Collagen I Promotes the Invasion of a Metastatic Breast Tumor Cell Line
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6696843cefb3d478b47216ba2b548720
https://doi.org/10.1158/0008-5472.22363893
https://doi.org/10.1158/0008-5472.22363893
Autor:
Yves Boucher, Rakesh K. Jain, Lance L. Munn, Xiaoye Wang, Jean Yannis Perentes, Trevor McKee, Michael Awad, Zoe N. Demou
Defective fibrillar collagen polymerization in primary tumors has been correlated with increased metastasis. However, it is unclear how collagen organization influences tumor invasion. In this study, we show that collagen I polymerized without telope
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::789e2c8646fb3ca8630734a2ab451a29
https://doi.org/10.1158/0008-5472.c.6493938
https://doi.org/10.1158/0008-5472.c.6493938
Abstract 117: Therapeutic targeting of hypoxia tolerance and oxygen consumption in pancreatic cancer
Autor:
Ji Zhang, Dan Cojocari, Pedro Boasquevisque, Mark Zaidi, Trevor McKee, Nikolina Radulovich, Ming-Sound Tsao, David Hedley, Marianne Koritzinsky, Bradley Wouters
Publikováno v:
Cancer Research. 82:117-117
Hypoxia is present in most solid tumours and has been clinically correlated with poor prognosis, aggressive disease, and resistance to therapy in multiple cancer including pancreatic ductal adenocarcinoma (PDAC). It has been shown PDAC hypoxia levels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1bfdd8787249a6f6bf9258f805377a47
https://doi.org/10.1158/1538-7445.am2022-117
https://doi.org/10.1158/1538-7445.am2022-117
Autor:
Xinle Wang, Catia Perciani, Xue-Zhong Ma, Chao Jiang, Justin Manuel, Sai Chung, Cornelia Thoeni, Trevor McKee, Ian McGilvray, Sonya Macparland
Digital image analysis is a widely employed technique to effectively reduce sample processing time and bias. Whole slide imaging and analysis of immunohistochemically stained sample slides allows for rapid cellular quantification and insight into sin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f882a5a30649f1c11fd8c5d7c5048770
https://doi.org/10.17504/protocols.io.bs6gnhbw
https://doi.org/10.17504/protocols.io.bs6gnhbw
Autor:
Takuo Emoto, Jessie Lu, Tharini Sivasubramaniyam, Hassaan Maan, Marwan Althagafi, Fred Fu, Felix Chiu, Shaun Pacheco, Angela Li, Aniqa Khan, Sharon Hyduk, Trevor McKee, Jean Jiang, Peter Libby, Bo Wang, Barry B. Rubin, Myron Cybulsky, Clinton S. Robbins
Publikováno v:
SSRN Electronic Journal.
Hematopoietic stem and progenitor cells reside within specialized niches. Colony stimulating factor 1 (CSF1) might serve as a monocyte niche factor given its critical role in regulating survival, proliferation, and differentiation of myeloid lineage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94d9e0cc704949e520e524380ba868d8
https://doi.org/10.2139/ssrn.3596597
https://doi.org/10.2139/ssrn.3596597