Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Trevor McGoldrick"'
Autor:
Sai Man Cheung, Kwok-Shing Chan, Nicholas Senn, Ehab Husain, Ravi Sharma, Trevor McGoldrick, Tanja Gagliardi, Yazan Masannat, Jiabao He
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 17, p 9303 (2024)
The deregulation of monounsaturated, polyunsaturated, and saturated fatty acids (MUFAs, PUFAs, SFAs) from de novo synthesis and hypoxia are central metabolic features of breast tumour. Early response markers for neoadjuvant chemotherapy (NACT) are cr
Externí odkaz:
https://doaj.org/article/0274f9d4d33947c0a017492c425ba00f
Autor:
Sai Man Cheung, Wing-Shan Wu, Nicholas Senn, Ravi Sharma, Trevor McGoldrick, Tanja Gagliardi, Ehab Husain, Yazan Masannat, Jiabao He
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionThe early identification of good responders to neoadjuvant chemotherapy (NACT) holds a significant potential in the optimal treatment of breast cancer. A recent Bayesian approach has been postulated to improve the accuracy of the intravox
Externí odkaz:
https://doaj.org/article/4d8ebf9665d44690b0fca1a0d6342d64
Autor:
Colin A. Semple, Charlie Gourley, Patricia Roxburgh, Andrew V. Biankin, Iain A. McNeish, J. Carl Barrett, Ruth March, Brian Dougherty, Athena Matakidou, Lynn McMahon, Darren Ennis, Brian McDade, Fiona Nussey, Melanie Mackean, Rosalind Glasspool, Suzanne Dowson, Nadeem Siddiqui, Neil McPhail, Trevor McGoldrick, Mairi Lennie, Michelle Ferguson, Ian Croy, Clare Bartos, Tzyvia Rye, C. Simon Herrington, Robert L. Hollis, Graeme R. Grimes, Michael Churchman, Alison Meynert, Ailith Ewing
SV loads in non-BRCA1/2 HR genes per sample by SV type
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::450cc60ad42d0ec76263ecb09722922f
https://doi.org/10.1158/1078-0432.22481309.v1
https://doi.org/10.1158/1078-0432.22481309.v1
Autor:
Colin A. Semple, Charlie Gourley, Patricia Roxburgh, Andrew V. Biankin, Iain A. McNeish, J. Carl Barrett, Ruth March, Brian Dougherty, Athena Matakidou, Lynn McMahon, Darren Ennis, Brian McDade, Fiona Nussey, Melanie Mackean, Rosalind Glasspool, Suzanne Dowson, Nadeem Siddiqui, Neil McPhail, Trevor McGoldrick, Mairi Lennie, Michelle Ferguson, Ian Croy, Clare Bartos, Tzyvia Rye, C. Simon Herrington, Robert L. Hollis, Graeme R. Grimes, Michael Churchman, Alison Meynert, Ailith Ewing
Purpose:The abundance and effects of structural variation at BRCA1/2 in tumors are not well understood. In particular, the impact of these events on homologous recombination repair deficiency (HRD) has yet to be demonstrated.Experimental Design:Explo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::429aee5bcef4db8eebfa46fee92e5bee
https://doi.org/10.1158/1078-0432.c.6530660.v1
https://doi.org/10.1158/1078-0432.c.6530660.v1
Autor:
Colin A. Semple, Charlie Gourley, Patricia Roxburgh, Andrew V. Biankin, Iain A. McNeish, J. Carl Barrett, Ruth March, Brian Dougherty, Athena Matakidou, Lynn McMahon, Darren Ennis, Brian McDade, Fiona Nussey, Melanie Mackean, Rosalind Glasspool, Suzanne Dowson, Nadeem Siddiqui, Neil McPhail, Trevor McGoldrick, Mairi Lennie, Michelle Ferguson, Ian Croy, Clare Bartos, Tzyvia Rye, C. Simon Herrington, Robert L. Hollis, Graeme R. Grimes, Michael Churchman, Alison Meynert, Ailith Ewing
Supplementary methods and supplementary figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c68503278e022aa60be8b0b03fbf981
https://doi.org/10.1158/1078-0432.22481327.v1
https://doi.org/10.1158/1078-0432.22481327.v1
Autor:
Dylan P, McClurg, Gordan, Urquhart, Trevor, McGoldrick, Subarnarekha, Chatterji, Zosia, Miedzybrodzka, Valerie, Speirs, Beatrix, Elsberger
Publikováno v:
Cancers. 14(13)
Male breast cancer (MBC) is a rare disease that accounts for less than 1% of all breast cancers and male malignancies. Despite recognised clinico-pathological and molecular differences to female breast cancer (FBC), the clinical management of MBC fol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dd3019186fb808286e9bea49045bfbf9
https://pubmed.ncbi.nlm.nih.gov/35804947
https://pubmed.ncbi.nlm.nih.gov/35804947
Autor:
Ravi Sharma, Nicholas Senn, Trevor McGoldrick, Yazan Masannat, Jiabao He, Sai Man Cheung, Vasiliki Mallikourti, Tanja Gagliardi, Steven D. Heys
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Lipid composition in breast cancer, a central marker of disease progression, can be non-invasively quantified using 2D MRS method of double quantum filtered correlation spectroscopy (DQF-COSY). The low signal to noise ratio (SNR), arising from signal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c36c6530371b6f1be9c20776e672285
https://doi.org/10.1038/s41598-020-74397-y
https://doi.org/10.1038/s41598-020-74397-y
Autor:
Ailith, Ewing, Alison, Meynert, Michael, Churchman, Graeme R, Grimes, Robert L, Hollis, C Simon, Herrington, Tzyvia, Rye, Clare, Bartos, Ian, Croy, Michelle, Ferguson, Mairi, Lennie, Trevor, McGoldrick, Neil, McPhail, Nadeem, Siddiqui, Suzanne, Dowson, Rosalind, Glasspool, Melanie, Mackean, Fiona, Nussey, Brian, McDade, Darren, Ennis, Lynn, McMahon, Athena, Matakidou, Brian, Dougherty, Ruth, March, J Carl, Barrett, Iain A, McNeish, Andrew V, Biankin, Patricia, Roxburgh, Charlie, Gourley, Colin A, Semple
Publikováno v:
Clin Cancer Res
PURPOSE: The abundance and effects of structural variation at BRCA1/2 in tumours are not well understood. In particular, the impact of these events on homologous recombination repair deficiency (HRD) has yet to be demonstrated. EXPERIMENTAL DESIGN: E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1b7db36b48f73e74b39ff4323118988d
https://pubmed.ncbi.nlm.nih.gov/33741650
https://pubmed.ncbi.nlm.nih.gov/33741650
Autor:
Trevor McGoldrick, Rosemarie Davidson, Z. Miedzybrodzka, Chee Yuan Tang, Christine Bell, Nicholas S. Reed, A. Sadozye, Mary Porteous, Pavlina Spiliopoulou, Kelly Rust, Tze Hui Fifi Phang, Fiona Nussey, Iain A. McNeish, Diane Stirling, Melanie Mackean, Charlie Gourley, R.M. Glasspool, Michelle Ferguson
Publikováno v:
BJOG: An International Journal of Obstetrics & Gynaecology. 125:1451-1458
To determine the rates of germline BRCA1 and BRCA2 mutations in Scottish patients with ovarian cancer, before and after a change in testing policy.Retrospective cohort study.Four cancer/genetics centres in Scotland.Patients with ovarian cancer underg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6791cf7f1c9070e2d4cf3dce3a2265b3
https://doi.org/10.1111/1471-0528.15171
https://doi.org/10.1111/1471-0528.15171
Autor:
Ilian Tchakov, Karin Leunen, Stanley B. Kaye, Susana Banerjee, Matthew G Krebs, L Rhoda Molife, Charlie Gourley, Kristine Pemberton, Helen Swaisland, Malcolm R Ranson, Joaquin Mateo, Michael Friedlander, Trevor McGoldrick, Peter McCormack, Gordon J. S. Rustin, Cristiana Sessa, Shibani Nicum, Yvette Drew, Ruth Plummer, Wendy Burke
Publikováno v:
Journal of Clinical Oncology. 30:3048-3048
3048 Background: We previously reported the comparative bioavailability of the capsule (CAP) formulation of olaparib and the more convenient new tablet (TAB) formulation (Molife et al ASCO 2010). We subsequently performed two separate dose expansions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::abc645fae0ebe45ae0a1a39ce29d370e
https://doi.org/10.1200/jco.2012.30.15_suppl.3048
https://doi.org/10.1200/jco.2012.30.15_suppl.3048