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pro vyhledávání: '"Trevor Lukey"'
Autor:
Floyd F. Snyder, Trevor Lukey
Publikováno v:
Canadian Journal of Biochemistry. 58:677-682
The optimal assay conditions and specificity for the principal reactions of purine nucleoside phosphorylation were studied in mouse thymocytes. The following relative activities were obtained for the nucleoside substrates: adenosine, 100; deoxyguanos
Publikováno v:
Biochemical Genetics. 21:323-332
A survey of 37 inbred strains for erythrocyte purine nucleoside phosphorylase activity showed a greater than threefold range. Six of these strains had significantly greater activity than the others, and all of the high-activity strains had the Np-2 e
Autor:
Floyd F. Snyder, Trevor Lukey
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 696:299-307
Metabolic regulation at a branch point may be determined primarily by relative enzyme activities and affinity for common substrate. Adenosine and deoxyadenosine are both phosphorylated and deaminated and their metabolism was studied in intact mouse t
Autor:
Trevor Lukey, Floyd F. Snyder
Publikováno v:
Biochemical Pharmacology. 32:1399-1406
The inhibition of S-adenosylhomocysteine hydrolase and accumulation of dATP in thymus, spleen and other tissues of mice treated with the adenosine deaminase inhibitor coformycin were studied in parallel with the competence of thymocytes and spleen le
Autor:
John F. Loman, Trevor Lukey, Ardythe E. Unger, Fred G. Biddle, Floyd F. Snyder, Kuldeep Neote
Publikováno v:
Biochemical genetics. 23(3-4)
An improved method for detecting four Np-1 (purine nucleoside phosphorylase) alleles in mouse erythrocytes by cellulose acetate electrophoresis is described. The previous linkage of Np-1 and Es-10 (esterase-10) was confirmed, with a map distance of 1
Publikováno v:
SIGCSE
This paper describes a debugging utility with some tutorial capabilities. It is designed to assist novice programmers in finding logic errors in syntactically correct programs. Flow and use analysis techniques are employed to aid in the recognition o
Autor:
Floyd F. Snyder, Trevor Lukey
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9781475703924
The inherited human deficiency of adenosine deaminase is associated with severe combined immunodeficiency disease1,2. Coformycin is a potent inhibitor of adenosine deaminase and markedly potentiates the in vitro toxicity of adenosine and deoxyadenosi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b31100707a51123a0ca63300caa121b0
https://doi.org/10.1007/978-1-4757-0390-0_38
https://doi.org/10.1007/978-1-4757-0390-0_38
Publikováno v:
Computers in biology and medicine. 18(6)
A series of routines, written in BASIC, have been developed to aid in the analysis, reporting and storage of physiological amino acid data used in the diagnosis and management of inherited metabolic disorders. The concentrations of 44 compounds are d
Autor:
Floyd F. Snyder, Trevor Lukey
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9781468485615
The human deficiencies of adenosine deaminase and purine nucleoside phosphorylase activities are associated with an accumulation of the purine deoxyribonucleoside triphosphates, dATP (1–4) and dGTP (4) respectively. In the absence of adenosine deam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::236fabc4c536a4f03765d79caade6cd9
https://doi.org/10.1007/978-1-4684-8559-2_42
https://doi.org/10.1007/978-1-4684-8559-2_42
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9781468445558
The inherited human deficiency of purine nucleoside phosphorylase is associated primarily with cellular immune dysfunction1. We have begun to screen for quantitative activity variants of purine nucleoside phosphorylase in Mus musculus in attempts to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30bbcf12d1de4c5e1a4986bf2976b3f8
https://doi.org/10.1007/978-1-4684-4553-4_79
https://doi.org/10.1007/978-1-4684-4553-4_79