Zobrazeno 1 - 10
of 118
pro vyhledávání: '"Trevor Leong"'
Autor:
Fiona Day, Swetha Sridharan, James Lynam, Craig Gedye, Catherine Johnson, Allison Fraser, Stephen R. Thompson, Michael Michael, Trevor Leong, Amitesh Roy, Mahesh Kumar, Andre van der Westhuizen, Gaik T. Quah, Hiren Mandaliya, Girish Mallesara, Joshua Sappiatzer, Christopher Oldmeadow, Jarad Martin
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background Oesophageal and gastrooesophageal junction (GOJ) carcinoma frequently present with dysphagia and de novo metastatic disease. There is scope to improve treatment paradigms to both address symptoms and improve survival. One method i
Externí odkaz:
https://doaj.org/article/b27cfdc539b34f84ba338f1a0fa88340
Autor:
Magnus Nilsson, Halla Olafsdottir, Gabriella Alexandersson von Döbeln, Fernanda Villegas, Giovanna Gagliardi, Mats Hellström, Qiao-Li Wang, Hemming Johansson, Val Gebski, Jakob Hedberg, Fredrik Klevebro, Sheraz Markar, Elizabeth Smyth, Pernilla Lagergren, Ghazwan Al-Haidari, Lars Cato Rekstad, Eirik Kjus Aahlin, Bengt Wallner, David Edholm, Jan Johansson, Eva Szabo, John V. Reynolds, CS Pramesh, Naveen Mummudi, Amit Joshi, Lorenzo Ferri, Rebecca KS Wong, Chris O’Callaghan, Jelena Lukovic, Kelvin KW Chan, Trevor Leong, Andrew Barbour, Mark Smithers, Yin Li, Xiaozheng Kang, Feng-Ming Kong, Yin-Kai Chao, Tom Crosby, Christiane Bruns, Hanneke van Laarhoven, Mark van Berge Henegouwen, Richard van Hillegersberg, Riccardo Rosati, Guillaume Piessen, Giovanni de Manzoni, Florian Lordick
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundThe globally dominant treatment with curative intent for locally advanced esophageal squamous cell carcinoma (ESCC) is neoadjuvant chemoradiotherapy (nCRT) with subsequent esophagectomy. This multimodal treatment leads to around 60% overall
Externí odkaz:
https://doaj.org/article/c303a3a5e5d942c9a1b8efb0a9d35233
Autor:
Ashika D Maharaj, Sue M Evans, John R Zalcberg, Liane J Ioannou, Marnie Graco, Daniel Croagh, Charles H C Pilgrim, Theresa Dodson, David Goldstein, Jennifer Philip, James G Kench, Neil D Merrett, Rachel E Neale, Kate White, Peter Evans, Trevor Leong, Sally E Green
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0243312 (2020)
BackgroundAccurate pre-operative imaging plays a vital role in patient selection for surgery and in allocating stage-appropriate therapies to patients diagnosed with pancreatic cancer (PC). This study aims to: (1) understand the current diagnosis and
Externí odkaz:
https://doaj.org/article/53299e901c074fbf94b1d5b845623270
Autor:
Sweet Ping Ng, Jennifer Tan, Glen Osbourne, Luke Williams, Mathias A.B. Bressel, Rodney J. Hicks, Eddie W.F. Lau, Julie Chu, Samuel Y.K. Ngan, Trevor Leong
Publikováno v:
Clinical and Translational Radiation Oncology, Vol 2, Iss C, Pp 76-82 (2017)
Background: This prospective study aims to determine the impact of PET/CT on radiotherapy planning and outcomes in patients with oesophageal cancer. Methods: All patients underwent PET/CT scanning in the radiotherapy treatment position, and received
Externí odkaz:
https://doaj.org/article/455c939baaaa4168a411598621ba3db5
Autor:
Xiangyu Chen, Robert Gaglione, Trevor Leong, Lauren Bednor, Teresa de Los Santos, Ed Luk, Michael Airola, Nancy M Hollingsworth
Publikováno v:
PLoS Genetics, Vol 14, Iss 11, p e1007832 (2018)
Meiotic recombination plays a critical role in sexual reproduction by creating crossovers between homologous chromosomes. These crossovers, along with sister chromatid cohesion, connect homologs to enable proper segregation at Meiosis I. Recombinatio
Externí odkaz:
https://doaj.org/article/9e8b7323a63d4f008854ac9a5198d8a2
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0173788 (2017)
PURPOSE:Fibrosis can be a disabling, severe side effect of radiotherapy that can occur in patients, and for which there is currently no effective treatment. The activins, proteins which are members of the TGFβ superfamily, have a major role in stimu
Externí odkaz:
https://doaj.org/article/03f775f04c3846ce9eef5b92b44c7699
Autor:
Sharon Pattison, Catherine Mitchell, Stephen Lade, Trevor Leong, Rita A Busuttil, Alex Boussioutas
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0183891 (2017)
Survival from gastric cancer remains poor, particularly in Western populations. Previous pre-clinical and subgroup analyses of clinical trials have suggested differing benefits from fluoropyrimidine-based chemotherapeutics for diffuse and intestinal
Externí odkaz:
https://doaj.org/article/418f83e4486241fab3276ab5a8384b14
Autor:
Helen B Forrester, Alesia Ivashkevich, Michael J McKay, Trevor Leong, David M de Kretser, Carl N Sprung
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77119 (2013)
Follistatin is a potent regulator of the inflammatory response and binds to and inhibits activin A action. Activin A is a member of the TGFβ protein superfamily which has regulatory roles in the inflammatory response and in the fibrotic process. Fib
Externí odkaz:
https://doaj.org/article/a543d001501c4ba980f876a7a1484090
Autor:
Mark Burns, Alexander G. Heriot, Nahal Varghayee, Ryan Anthony Agas, Jing Xie, Julie Chu, Wei Mou, Samuel Y Ngan, Joseph Sia, Trevor Leong
Publikováno v:
Clinical Colorectal Cancer. 21:e102-e112
Background To analyze the long-term outcomes and prognostic value of hematological parameters in anal cancer patients receiving intensity-modulated radiation therapy (IMRT). Materials Hospital records of consecutive patients with anal squamous cell c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0179b17504d12add88ebaf4ae5a769f
https://doi.org/10.1016/j.clcc.2021.10.005
https://doi.org/10.1016/j.clcc.2021.10.005
Publikováno v:
Clinical Colorectal Cancer. 21:63-70
Colorectal cancer is the 3rd most commonly diagnosed cancer, with rectal cancer accounting for 30% of cases. The current standard of care curative treatment for locally advanced rectal cancer is (chemo)radiotherapy followed by surgery and adjuvant ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb9c643f40bd6c6f9401ec43f01970a5
https://doi.org/10.1016/j.clcc.2021.10.008
https://doi.org/10.1016/j.clcc.2021.10.008