Výsledky vyhledávání - "Trevor L. Olson"

Extension of furopyrimidine nucleosides with 5-alkynyl substituent: Synthesis, high fluorescence, and antiviral effect in the absence of free ribose hydroxyl groups

Autor: Dariusz Korczyński, Robert Snoeck, Renata Kaczmarek, Dylan J. Twardy, Graciela Andrei, Rafał Dolot, Roman Dembinski, Trevor L. Olson, Kraig A. Wheeler

Publikováno v: European Journal of Medicinal Chemistry

A novel methodology to access alkynyl nucleoside analogs was elaborated. Highly fluorescent 5-alkynylfuropyrimidines were synthesized (97-46%) and their antiviral properties investigated in vitro. Regiochemistry of the functionalization was achieved

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::931fe762f9f430ea13cd1fe86bf41baf
https://pubmed.ncbi.nlm.nih.gov/33039724

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