Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Trevor J. Mathias"'
Autor:
Keyata N. Thompson, Julia A. Ju, Eleanor C. Ory, Stephen J. P. Pratt, Rachel M. Lee, Trevor J. Mathias, Katarina T. Chang, Cornell J. Lee, Olga G. Goloubeva, Patrick C. Bailey, Kristi R. Chakrabarti, Christopher M. Jewell, Michele I. Vitolo, Stuart S. Martin
Publikováno v:
Breast Cancer Research, Vol 24, Iss 1, Pp 1-21 (2022)
Abstract Clinical cancer imaging focuses on tumor growth rather than metastatic phenotypes. The microtubule-depolymerizing drug, Vinorelbine, reduced the metastatic phenotypes of microtentacles, reattachment and tumor cell clustering more than tumor
Externí odkaz:
https://doaj.org/article/16b3a6a66cbd4783a10d41a52c7ae93f
Autor:
Megan B. Stemberger, Julia A. Ju, Keyata N. Thompson, Trevor J. Mathias, Alexandra E. Jerrett, Katarina T. Chang, Eleanor C. Ory, David A. Annis, Makenzy L. Mull, Darin E. Gilchrist, Michele I. Vitolo, Stuart S. Martin
Publikováno v:
Cells, Vol 12, Iss 9, p 1266 (2023)
Levels of hydrogen peroxide are highly elevated in the breast tumor microenvironment compared to normal tissue. Production of hydrogen peroxide is implicated in the mechanism of action of many anticancer therapies. Several lines of evidence suggest h
Externí odkaz:
https://doaj.org/article/fff120d70ebf46c392e1750ff30f723f
Autor:
Katarina T. Chang, Keyata N. Thompson, Stephen J. P. Pratt, Julia A. Ju, Rachel M. Lee, Trevor J. Mathias, Makenzy L. Mull, David A. Annis, Eleanor C. Ory, Megan B. Stemberger, Michele I. Vitolo, Stuart S. Martin
Publikováno v:
Cancers, Vol 15, Iss 3, p 884 (2023)
Cytoskeletal remodeling in circulating tumor cells (CTCs) facilitates metastatic spread. Previous oncology studies examine sustained aberrant calcium (Ca2+) signaling and cytoskeletal remodeling scrutinizing long-term phenotypes such as tumorigenesis
Externí odkaz:
https://doaj.org/article/246052652eec4a51a1c2f6d1aae3e91e
Autor:
Rebecca G. Nowak, Lisa M. Schumaker, Nicholas P. Ambulos, Nicaise Ndembi, Wuese Dauda, Chinedu H. Nnaji, Andrew Mitchell, Trevor J. Mathias, Paul Jibrin, Teresa M. Darragh, Oluwole Olaomi, Trevor A. Crowell, Stefan D. Baral, Manhattan E. Charurat, Søren M. Bentzen, Joel M. Palefsky, Kevin J. Cullen, Manhattan Charurat, Julie Ake, Aka Abayomi, Sylvia Adebajo, Stefan Baral, Trevor Crowell, Charlotte Gaydos, Sosthenes Ketende, Afoke Kokogho, Jennifer Malia, Olumide Makanjuola, Nelson Michael, Nicaise Ndemb, Rebecca Nowak, Oluwasolape Olawore, Zahra Parker, Sheila Peel, Habib Ramadhani, Merlin Robb, Cristina Rodriguez-Hart, Eric Sanders-Buell, Elizabeth Shoyemi, Sodsai Tovanabutra, Sandhya Vasan
Publikováno v:
Papillomavirus Research, Vol 10, Iss , Pp 100200- (2020)
Background: Anal precancers and cancers can be detected during screening with high-resolution anoscopy (HRA). The sensitivity of HRA depends on the burden and duration of human papillomavirus (HPV) among those screened as well as anoscopist proficien
Externí odkaz:
https://doaj.org/article/2028881ccea8440d8cc4fb7e474e3bf3
Autor:
Trevor J. Mathias, Julia A. Ju, Rachel M. Lee, Keyata N. Thompson, Makenzy L. Mull, David A. Annis, Katarina T. Chang, Eleanor C. Ory, Megan B. Stemberger, Takashi Hotta, Ryoma Ohi, Michele I. Vitolo, Marie-Jo Moutin, Stuart S. Martin
Publikováno v:
Cancers, Vol 14, Iss 7, p 1707 (2022)
Post-translational modifications (PTMs) of the microtubule network impart differential functions across normal cell types and their cancerous counterparts. The removal of the C-terminal tyrosine of α-tubulin (deTyr-Tub) as performed by the tubulin c
Externí odkaz:
https://doaj.org/article/a9e03d3afcd844afa649f9b0461c12df
Autor:
Rebecca G. Nowak, Nicholas P. Ambulos, Lisa M. Schumaker, Trevor J. Mathias, Ruth A. White, Jennifer Troyer, David Wells, Manhattan E. Charurat, Søren M. Bentzen, Kevin J. Cullen
Publikováno v:
Virology Journal, Vol 14, Iss 1, Pp 1-5 (2017)
Abstract Background Our next generation sequencing (NGS)-based human papillomavirus (HPV) genotyping assay showed a high degree of concordance with the Roche Linear Array (LA) with as little as 1.25 ng formalin-fixed paraffin-embedded-derived genomic
Externí odkaz:
https://doaj.org/article/f89ffcd77c114602af780c9c30f4a941
Publikováno v:
Biomolecules, Vol 10, Iss 12, p 1646 (2020)
Long noncoding RNA differentiation antagonizing nonprotein coding RNA (lncRNA-DANCR) is associated with poor prognosis in multiple cancers, and promotes cancer stemness and invasion. However, the exact mechanisms by which DANCR promotes non-small cel
Externí odkaz:
https://doaj.org/article/31ecd7236ba549ddab180d0bde000ea0
Publikováno v:
Cancers, Vol 12, Iss 3, p 743 (2020)
The metastatic cascade consists of multiple complex steps, but the belief that it is a linear process is diminishing. In order to metastasize, cells must enter the blood vessels or body cavities (depending on the cancer type) via active or passive me
Externí odkaz:
https://doaj.org/article/f8ea250234754cce82ab07095e475a69
Autor:
Maria R. Baer, Danilo Perrotti, Adriana E. Tron, Dennis Huszar, Manfred Kraus, Eduardo Davila, Rossana Trotta, Mario Scarpa, Trevor J. Mathias, Rena G. Lapidus, Kshama A. Doshi, Patrick R. Baldwin, Karthika Natarajan, Shivani Kapoor
AZD1208 and quizartinib co-treatment was well tolerated in the orthotopic model.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1aa4dc3b4b50fe54ac11960a14462b2d
https://doi.org/10.1158/1078-0432.22463250.v1
https://doi.org/10.1158/1078-0432.22463250.v1
Autor:
Maria R. Baer, Danilo Perrotti, Adriana E. Tron, Dennis Huszar, Manfred Kraus, Eduardo Davila, Rossana Trotta, Mario Scarpa, Trevor J. Mathias, Rena G. Lapidus, Kshama A. Doshi, Patrick R. Baldwin, Karthika Natarajan, Shivani Kapoor
Purpose: fms-like tyrosine kinase 3 internal tandem duplication (FLT3-ITD) is present in 30% of acute myeloid leukemia (AML), and these patients have short disease-free survival. FLT3 inhibitors have limited and transient clinical activity, and concu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2be4683261314d8ff2b7e0db830d39d2
https://doi.org/10.1158/1078-0432.c.6525348
https://doi.org/10.1158/1078-0432.c.6525348