Zobrazeno 1 - 10 of 14 pro vyhledávání: '"Trevor I. Prior"'
1
Stereochemistry and drug efficacy and development: relevance of chirality to antidepressant and antipsychotic drugs
Autor: Trevor I. Prior, Glen B Baker
Publikováno v: Annals of Medicine. 34:537-543
Many drugs contain a chiral center or a center of unsaturation, or such centers result during metabolism of these drugs. Often such drugs are marketed as a mixture of the resultant enantiomers (racemates) or of geometric isomers, respectively. These
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae6202d873ee81b9e402c4b0d2d0cca5
https://doi.org/10.1080/078538902321117742
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2
Investigation of Turner syndrome in schizophrenia
Autor: Pierre Chue, Philip Tibbo, Trevor I. Prior
Publikováno v: American Journal of Medical Genetics. 96:373-378
Both Turner syndrome and schizophrenia are relatively infrequent conditions. Consequently, individuals having both illnesses are rare. Previous reviews of sex chromosome abnormalities in schizophrenia have focused primarily on the presence of supernu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8f72368ac8aca1015a102fb3ecd66c82
https://doi.org/10.1002/1096-8628(20000612)96:3<373::aid-ajmg26>3.0.co
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3
Drug metabolism and atypical antipsychotics
Autor: Pierre Chue, Glen B. Baker, Trevor I. Prior, Philip Tibbo
Publikováno v: European Neuropsychopharmacology. 9:301-309
The introduction of the atypical antipsychotics clozapine, risperidone, olanzapine, quetiapine and sertindole for the treatment of schizophrenia has coincided with an increased awareness of the potential of drug-drug interactions, particularly involv
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ef6ae788f7f4bb408c23426775bbba3
https://doi.org/10.1016/s0924-977x(98)00040-6
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4
Metabolism of atypical antipsychotics: involvement of cytochrome p450 enzymes and relevance for drug-drug interactions
Autor: Trevor I. Prior, Serdar M. Dursun, Glen B. Baker, Liana Urichuk
Publikováno v: Current drug metabolism. 9(5)
The involvement of cytochrome P450 (CYP) enzymes in the metabolism of the atypical (secondgeneration) antipsychotics clozapine, risperidone, olanzapine, quetiapine, ziprasidone, aripiprazole, paliperidone and amisulpride is reviewed, and the possible
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::492abfeaf98b491acfb32b4b4e1f1ddb
https://pubmed.ncbi.nlm.nih.gov/18537577
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5
The relevance of neuroactive steroids in schizophrenia, depression, and anxiety disorders
Autor: Erin M. MacKenzie, Trevor I. Prior, Jean-Michel Le Mellédo, Glen B. Baker, John Odontiadis
Publikováno v: Cellular and molecular neurobiology. 27(5)
1. Neuroactive steroids are steroid hormones that exert rapid, nongenomic effects at ligand-gated ion channels. There is increasing awareness of the possible role of these steroids in the pathology and manifestation of symptoms of psychiatric disorde
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e27e7743e094e431c69e1f2e1548b79d
https://pubmed.ncbi.nlm.nih.gov/17235696
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7
Translocation mediated by domain II of Pseudomonas exotoxin A: transport of barnase into the cytosol
Autor: Ira Pastan, David J. FitzGerald, Trevor I. Prior
Publikováno v: Biochemistry. 31(14)
Pseudomonas exotoxin A (PE) is a protein toxin composed of three structural domains. Functional analysis of PE has revealed that domain I is the cell-binding domain and that domain III functions in ADP ribosylation. Domain II was originally designate
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74e49b3fa855437226dcede29d0b5b93
https://pubmed.ncbi.nlm.nih.gov/1567815
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