Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Trevor F. Moraes"'
Autor:
Riya Shah, Thomas C. Panagiotou, Gregory B. Cole, Trevor F. Moraes, Brigitte D. Lavoie, Christopher A. McCulloch, Andrew Wilde
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Cytokinesis is the final step of the cell division cycle that leads to the formation of two new cells. Successful cytokinesis requires significant remodelling of the plasma membrane by spatially distinct β- and γ-actin networks. These netw
Externí odkaz:
https://doaj.org/article/1f9d612d05f84b62a0e2a0218506e856
Autor:
Jamie E. Fegan, Regula C. Waeckerlin, Liyuwork Tesfaw, Epshita A. Islam, Getaw Deresse, Dawit Dufera, Eyob Assefa, Wubet Woldemedhin, Abinet Legesse, Mirtneh Akalu, Berecha Bayissa, Quynh Huong Nguyen, Dixon Ng, Sang Kyun Ahn, Anthony B. Schryvers, Takele A. Tefera, Trevor F. Moraes, Scott D. Gray-Owen
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundPasteurella multocida is a bacterial pathogen that causes a variety of infections across diverse animal species, with one of the most devastating associated diseases being hemorrhagic septicemia. Outbreaks of hemorrhagic septicemia in cattl
Externí odkaz:
https://doaj.org/article/db111532093946448a33dc7edaa8c349
Autor:
Eve A. Maunders, Matthew W. Giles, Katherine Ganio, Bliss A. Cunningham, Vicki Bennett-Wood, Gregory B. Cole, Dixon Ng, Christine C. Lai, Stephanie L. Neville, Trevor F. Moraes, Christopher A. McDevitt, Aimee Tan
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2024)
Klebsiella pneumoniae is a World Health Organization priority pathogen and a significant clinical concern for infections of the respiratory and urinary tracts due to widespread and increasing resistance to antimicrobials. In the absence of a vaccine,
Externí odkaz:
https://doaj.org/article/4a4a93bde406448ca8bda42f7899b3c0
Autor:
Mary R. Ferguson, Kristina N. Delgado, Shannon McBride, Isabel C. Orbe, Carson J. La Vake, Melissa J. Caimano, Qiana Mendez, Trevor F. Moraes, Anthony B. Schryvers, M. Anthony Moody, Justin D. Radolf, Michael P. Weiner, Kelly L. Hawley
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionSyphilis, a sexually transmitted infection caused by the spirochete Treponema pallidum (Tp), is resurging globally. Tp’s repertoire of outer membrane proteins (OMPs) includes BamA (β-barrel assembly machinery subunit A/TP0326), a bipar
Externí odkaz:
https://doaj.org/article/269f6fb6d31f482c8031d99450697c02
Autor:
Thomas J. Bateman, Megha Shah, Timothy Pham Ho, Hyejin Esther Shin, Chuxi Pan, Greg Harris, Jamie E. Fegan, Epshita A. Islam, Sang Kyun Ahn, Yogesh Hooda, Scott D. Gray-Owen, Wangxue Chen, Trevor F. Moraes
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nutrient acquisition is crucial for the growth of pathogens within their hosts. Here, Bateman et al. identify a set of proteins required for heme uptake from host hemoglobin and serum albumin in the pathogen Acinetobacter baumannii.
Externí odkaz:
https://doaj.org/article/f80f4a568d8744c5b4768aa9ef00b6d1
Autor:
Anan Chen, Luisa Ulloa Severino, Thomas C. Panagiotou, Trevor F. Moraes, Darren A. Yuen, Brigitte D. Lavoie, Andrew Wilde
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
During cell division, the actin cytoskeletal network at both the equatorial contractile ring and cell cortex are known to play a role, but the regulation of γ-actin during cytokinesis is less well understood. Here, the authors show that recruitment
Externí odkaz:
https://doaj.org/article/0a7e937311fe4867849f9a4f60295ef9
Autor:
Annoj Thavalingam, Zhi Cheng, Bianca Garcia, Xue Huang, Megha Shah, Wei Sun, Min Wang, Lucas Harrington, Sungwon Hwang, Yurima Hidalgo-Reyes, Erik J. Sontheimer, Jennifer Doudna, Alan R. Davidson, Trevor F. Moraes, Yanli Wang, Karen L. Maxwell
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Anti-CRISPR proteins offer the means of regulating CRISPR-Cas9 activity. Here the authors present the structure and biochemical characterisation of AcrIIC2 Nme alone and in complex with Cas9.
Externí odkaz:
https://doaj.org/article/e4066aeabab14fe3b824f6c38d4f8d8d
Autor:
Jamie E. Fegan, Charles Calmettes, Epshita A. Islam, Sang Kyun Ahn, Somshukla Chaudhuri, Rong-hua Yu, Scott D. Gray-Owen, Trevor F. Moraes, Anthony B. Schryvers
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
The surface transferrin receptor proteins from Neisseria gonorrhoeae have been recognized as ideal vaccine targets due to their critical role in survival in the human male genitourinary tract. Recombinant forms of the surface lipoprotein component of
Externí odkaz:
https://doaj.org/article/eb42652bd6064b069b91509da258e22d
Autor:
April Pawluk, Megha Shah, Marios Mejdani, Charles Calmettes, Trevor F. Moraes, Alan R. Davidson, Karen L. Maxwell
Publikováno v:
mBio, Vol 8, Iss 6 (2017)
ABSTRACT CRISPR (clustered regularly interspaced short palindromic repeat)-Cas adaptive immune systems are prevalent defense mechanisms in bacteria and archaea. They provide sequence-specific detection and neutralization of foreign nucleic acids such
Externí odkaz:
https://doaj.org/article/638a3e556a714bbc9c1150d62a69a2df
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 7 (2017)
The surfaces of many Gram-negative bacteria are decorated with soluble proteins anchored to the outer membrane via an acylated N-terminus; these proteins are referred to as surface lipoproteins or SLPs. In Neisseria meningitidis, SLPs such as transfe
Externí odkaz:
https://doaj.org/article/9d2ab4ea75864ba98783f1f34a6c4e57