Zobrazeno 1 - 10
of 157
pro vyhledávání: '"Trevor D, Lawley"'
Autor:
Leah Cuthbertson, Ulrike Löber, Jonathan S. Ish-Horowicz, Claire N. McBrien, Colin Churchward, Jeremy C. Parker, Michael T. Olanipekun, Conor Burke, Aisling McGowan, Gwyneth A. Davies, Keir E. Lewis, Julian M. Hopkin, Kian Fan Chung, Orla O’Carroll, John Faul, Joy Creaser-Thomas, Mark Andrews, Robin Ghosal, Stefan Piatek, Saffron A. G. Willis-Owen, Theda U. P. Bartolomaeus, Till Birkner, Sarah Dwyer, Nitin Kumar, Elena M. Turek, A. William Musk, Jennie Hui, Michael Hunter, Alan James, Marc-Emmanuel Dumas, Sarah Filippi, Michael J. Cox, Trevor D. Lawley, Sofia K. Forslund, Miriam F. Moffatt, William. O. C. Cookson
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-14 (2024)
Abstract Microbial communities at the airway mucosal barrier are conserved and highly ordered, in likelihood reflecting co-evolution with human host factors. Freed of selection to digest nutrients, the airway microbiome underpins cognate management o
Externí odkaz:
https://doaj.org/article/fa0a86718fb4447f9b20ab7e4ec9f322
Autor:
Tommi Mäklin, Harry A. Thorpe, Anna K. Pöntinen, Rebecca A. Gladstone, Yan Shao, Maiju Pesonen, Alan McNally, Pål J. Johnsen, Ørjan Samuelsen, Trevor D. Lawley, Antti Honkela, Jukka Corander
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Opportunistic bacterial pathogen species frequently colonise the human gut as a normal part of the ecosystem but strain-level colonisation and competition dynamics in healthy hosts is yet to be established. Authors seek to understand the relationship
Externí odkaz:
https://doaj.org/article/8e93f7b998b34aaf9e526e352acf40b3
Autor:
Niels van Best, Maria Gloria Dominguez-Bello, Mathias W. Hornef, Eldin Jašarević, Katri Korpela, Trevor D. Lawley
Publikováno v:
Microbiome, Vol 10, Iss 1, Pp 1-9 (2022)
Externí odkaz:
https://doaj.org/article/53ef8b68daaa4e0c8f8dc3deb4daf62b
Autor:
Samuel C. Forster, Junyan Liu, Nitin Kumar, Emily L. Gulliver, Jodee A. Gould, Alejandra Escobar-Zepeda, Tapoka Mkandawire, Lindsay J. Pike, Yan Shao, Mark D. Stares, Hilary P. Browne, B. Anne Neville, Trevor D. Lawley
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
Here, Forster et al. compare 1354 cultured commensal strains (540 species) to 45,403 pathogen strains (12 species), identifying 64,188 MGE-mediated antibiotic resistance gene transfer events between the two groups, and show that 15 broad host range M
Externí odkaz:
https://doaj.org/article/6b3f3a14687c4d9ea992587fbf554cd6
Autor:
Nicola A. Thompson, Grant D. Stewart, Sarah J. Welsh, Gary J. Doherty, Matthew J. Robinson, B. Anne Neville, Kevin Vervier, Simon R. Harris, David J. Adams, Katy Dalchau, David Bruce, Nikolaos Demiris, Trevor D. Lawley, Pippa G. Corrie
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-11 (2022)
Abstract Background The gut microbiome is implicated as a marker of response to immune checkpoint inhibitors (ICI) based on preclinical mouse models and preliminary observations in limited patient series. Furthermore, early studies suggest faecal mic
Externí odkaz:
https://doaj.org/article/715ab5e8f0424381af262366a64b1240
Autor:
Albert Koulman, Kelsey Jones, James Berkley, Judd Walson, Eric Houpt, David S. Wishart, Christina L. Lancioni, Moses Ngari, Lei Xia, James M. Njunge, Abdoulaye Hama Diallo, Kirkby Tickell, Md. Amran Gazi, Abu Sadat Mohammad Sayeem Bin Shahid, Zaubina Kazi, Ali Saleem, Caroline Tigoi, Syed Ali, Emily Yoshioka, Ezekiel Mupere, Moses Mburu, Mohammod Jobayer Chisti, Bonface Gichuki, Narshion Ngao, Wilson Gumbi, Elisha Omer, Robert Bandsma, Benson Singa, Wieger Voskuijl, Tahmeed Ahmed, Alex Macharia, Thomas N. Williams, Anna Mitchel, Johnstone Makale, Joe Gogain, Jessica Williams, Rupasri Mandal, Nebojsa Janjic, Michael Routledge, Hang Wu, Camilo Espinosa, Yun Yun Gong, Jie Liu, Nima Aghaeepour, Hilary Browne, Trevor D. Lawley, Doreen Rwigi, Yan Shao, Timothy Kaburu, Kevin Kariuki, Lisa Gartner, Holm H. Uhlig
Publikováno v:
Gates Open Research, Vol 6 (2022)
Introduction: Many acutely ill children in low- and middle-income settings have a high risk of mortality both during and after hospitalisation despite guideline-based care. Understanding the biological mechanisms underpinning mortality may suggest op
Externí odkaz:
https://doaj.org/article/4f784e51afb14738813820fdbf1f5a7d
Autor:
Alba Cortés, John Martin, Bruce A Rosa, Klara A Stark, Simon Clare, Catherine McCarthy, Katherine Harcourt, Cordelia Brandt, Charlotte Tolley, Trevor D Lawley, Makedonka Mitreva, Matthew Berriman, Gabriel Rinaldi, Cinzia Cantacessi
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 16, Iss 10, p e0010878 (2022)
Increasing evidence shows that the host gut microbiota might be involved in the immunological cascade that culminates with the formation of tissue granulomas underlying the pathophysiology of hepato-intestinal schistosomiasis. In this study, we inves
Externí odkaz:
https://doaj.org/article/2f734bc1a5e143bc8d3116a37f7fc078
Host adaptation in gut Firmicutes is associated with sporulation loss and altered transmission cycle
Autor:
Hilary P. Browne, Alexandre Almeida, Nitin Kumar, Kevin Vervier, Anne T. Adoum, Elisa Viciani, Nicholas J. R. Dawson, Samuel C. Forster, Claire Cormie, David Goulding, Trevor D. Lawley
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-20 (2021)
Abstract Background Human-to-human transmission of symbiotic, anaerobic bacteria is a fundamental evolutionary adaptation essential for membership of the human gut microbiota. However, despite its importance, the genomic and biological adaptations un
Externí odkaz:
https://doaj.org/article/921bbadd3ff24b9e8f397afe36e63df8
Autor:
Daniela Costa, Simon Lévesque, Nitin Kumar, Pablo Fresia, Ignacio Ferrés, Trevor D. Lawley, Gregorio Iraola
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Campylobacter hyointestinalis is an emerging pathogen currently divided in two subspecies: C. hyointestinalis subsp. lawsonii which is predominantly recovered from pigs, and C. hyointestinalis subsp. hyointestinalis which can be found in a m
Externí odkaz:
https://doaj.org/article/4057af738fa64e8ab8ea643e411b70d7
Autor:
Monique J.T. Crobach, Bastian V.H. Hornung, Cees Verduin, Margreet C. Vos, Joost Hopman, Nitin Kumar, Celine Harmanus, Ingrid Sanders, Elisabeth M. Terveer, Mark D. Stares, Trevor D. Lawley, Ed J. Kuijper
Publikováno v:
Clinical Microbiology and Infection, 29(7), 891-896. Elsevier Ltd.
Objectives: To assess the value of screening for Clostridioides difficile colonization (CDC) at hospital admission in an endemic setting. Methods: A multi-centre study was conducted at four hospitals located across the Netherlands. Newly admitted pat