Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Trevor Barlowe"'
Autor:
Amit Verma, Michael G. Kharas, H. Joachim Deeg, Marc H.G.P. Raaijmakers, Ulrich Steidl, Britta Will, Jacqueline Boultwood, Andrea Pellagatti, Siddhartha Mukherjee, John M. Greally, Jinghang Zhang, Kith Pradhan, Yiting Yu, Konrad Hochedlinger, Peter Aplan, Kira Gritsman, Cecilia Yeung, Amittha Wickrema, Davendra Sohal, Orsi Giricz, Prafulla Bhagat, Robert Lopez, Remi Laurence, Vineeth Sukrithan, Iaonnis Mantzaris, Nandini Ramachandra, Suman Kambhampati, Remco M. Hoogenboezem, Mathijs A. Sanders, A. Mario Marcondes, Elianna Amin, Patrick Tivnan, Gaurav S. Choudhary, Dagny Von Ahrens, A. Trevor Barlowe, Matthias Bartenstein, Si Chen, Tushar D. Bhagat
Supp Table 1: MDS Patient Disease Characteristics Supp Table 2: Pathways affected by hypermethylation in MDS stroma Supp Table 3: Genes that are methylated and underexpressed in MDS stroma Supp Table 4. MDS patient characteristics for primary MSC sam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dae0ab1066c8473f458390b001954c2
https://doi.org/10.1158/0008-5472.22414418.v1
https://doi.org/10.1158/0008-5472.22414418.v1
Autor:
Amit Verma, Michael G. Kharas, H. Joachim Deeg, Marc H.G.P. Raaijmakers, Ulrich Steidl, Britta Will, Jacqueline Boultwood, Andrea Pellagatti, Siddhartha Mukherjee, John M. Greally, Jinghang Zhang, Kith Pradhan, Yiting Yu, Konrad Hochedlinger, Peter Aplan, Kira Gritsman, Cecilia Yeung, Amittha Wickrema, Davendra Sohal, Orsi Giricz, Prafulla Bhagat, Robert Lopez, Remi Laurence, Vineeth Sukrithan, Iaonnis Mantzaris, Nandini Ramachandra, Suman Kambhampati, Remco M. Hoogenboezem, Mathijs A. Sanders, A. Mario Marcondes, Elianna Amin, Patrick Tivnan, Gaurav S. Choudhary, Dagny Von Ahrens, A. Trevor Barlowe, Matthias Bartenstein, Si Chen, Tushar D. Bhagat
Supplementary Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7088e12509540b55682090ae288f6768
https://doi.org/10.1158/0008-5472.22414421
https://doi.org/10.1158/0008-5472.22414421
Autor:
Amit Verma, Michael G. Kharas, H. Joachim Deeg, Marc H.G.P. Raaijmakers, Ulrich Steidl, Britta Will, Jacqueline Boultwood, Andrea Pellagatti, Siddhartha Mukherjee, John M. Greally, Jinghang Zhang, Kith Pradhan, Yiting Yu, Konrad Hochedlinger, Peter Aplan, Kira Gritsman, Cecilia Yeung, Amittha Wickrema, Davendra Sohal, Orsi Giricz, Prafulla Bhagat, Robert Lopez, Remi Laurence, Vineeth Sukrithan, Iaonnis Mantzaris, Nandini Ramachandra, Suman Kambhampati, Remco M. Hoogenboezem, Mathijs A. Sanders, A. Mario Marcondes, Elianna Amin, Patrick Tivnan, Gaurav S. Choudhary, Dagny Von Ahrens, A. Trevor Barlowe, Matthias Bartenstein, Si Chen, Tushar D. Bhagat
The bone marrow microenvironment influences malignant hematopoiesis, but how it promotes leukemogenesis has not been elucidated. In addition, the role of the bone marrow stroma in regulating clinical responses to DNA methyltransferase inhibitors (DNM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f33ca2e7ce5f82dc31f12f52089be88
https://doi.org/10.1158/0008-5472.c.6508973.v1
https://doi.org/10.1158/0008-5472.c.6508973.v1
Autor:
Amit Verma, Michael G. Kharas, H. Joachim Deeg, Marc H.G.P. Raaijmakers, Ulrich Steidl, Britta Will, Jacqueline Boultwood, Andrea Pellagatti, Siddhartha Mukherjee, John M. Greally, Jinghang Zhang, Kith Pradhan, Yiting Yu, Konrad Hochedlinger, Peter Aplan, Kira Gritsman, Cecilia Yeung, Amittha Wickrema, Davendra Sohal, Orsi Giricz, Prafulla Bhagat, Robert Lopez, Remi Laurence, Vineeth Sukrithan, Iaonnis Mantzaris, Nandini Ramachandra, Suman Kambhampati, Remco M. Hoogenboezem, Mathijs A. Sanders, A. Mario Marcondes, Elianna Amin, Patrick Tivnan, Gaurav S. Choudhary, Dagny Von Ahrens, A. Trevor Barlowe, Matthias Bartenstein, Si Chen, Tushar D. Bhagat
Supp Fig 1 : SFRP1 methylation with coculture Supp Fig 2 : Validation of methylation changes with stroma and leukemic cell coculture Supp Fig 3: FRZB upregulation in MDS stroma after 5-Azacytidine treatment SuppFig 4: FRZB knockdown leads to partial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0489f392c2b7fdad35acf602880e9cba
https://doi.org/10.1158/0008-5472.22414424.v1
https://doi.org/10.1158/0008-5472.22414424.v1
Autor:
Rebecca M. Baron, James M. Cleary, Alan Cubre, Jonathan H Young, Andrew H. Lichtman, Yannis K. Valtis, Trevor Barlowe, Jason L. Hornick, Nikroo Hashemi, Lei Zhao
Publikováno v:
Clinics and research in hepatology and gastroenterology. 46(3)
We present the case of a 61-year-old woman who presented with acutely worsening right upper quadrant pain and was found to be in acute liver failure with Klebsiella pneumoniae bacteremia. Despite aggressive intensive care management, the patient ulti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a263816c6f392b85efdc5993e11e3c22
https://pubmed.ncbi.nlm.nih.gov/34800682
https://pubmed.ncbi.nlm.nih.gov/34800682
Autor:
Diu Nguyen, Camila Prieto, Zhaoqi Liu, Justin Wheat, Alexander Perez, Saroj Gourkanti, Timothy Chou, Ersilia Barin, Anthony Velleca, Thomas Rohwetter, Arthur Chow, James Taggart, Angela Savino, Katerina Hoskova, Meera Dhodapkar, Alexandra Schurer, trevor Barlowe, Christina Leslie, Ly Vu, Ulrich Steidl, Raul Rabandan, Michael Kharas
Publikováno v:
Experimental Hematology. 100:S30-S31
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe3f44dd20545ffc863cb48b71f0951e
https://doi.org/10.1016/j.exphem.2021.12.372
https://doi.org/10.1016/j.exphem.2021.12.372
Autor:
A. Trevor Barlowe, Vineeth Sukrithan, Remco Hoogenboezem, Remi Laurence, Jinghang Zhang, Britta Will, Marc H.G.P. Raaijmakers, Mathijs A. Sanders, Amit Verma, Michael G. Kharas, Si Chen, Robert Lopez, Gaurav Choudhary, Nandini Ramachandra, Prafullla Bhagat, Jacqueline Boultwood, A. Mario Marcondes, Iaonnis Mantzaris, Andrea Pellagatti, John M. Greally, Orsolya Giricz, Matthias Bartenstein, Suman Kambhampati, Cecilia Yeung, Peter D. Aplan, Konrad Hochedlinger, Kira Gritsman, Davendra Sohal, Elianna M. Amin, Tushar D. Bhagat, Siddhartha Mukherjee, Patrick Tivnan, H. Joachim Deeg, Dagny Von Ahrens, Ulrich Steidl, Amittha Wickrema, Yiting Yu, Kith Pradhan
Publikováno v:
Cancer Research, 77(18), 4846-4857. American Association for Cancer Research Inc.
The bone marrow microenvironment influences malignant hematopoiesis, but how it promotes leukemogenesis has not been elucidated. In addition, the role of the bone marrow stroma in regulating clinical responses to DNA methyltransferase inhibitors (DNM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8368e2835114011e038f7e518da02fc
https://pure.eur.nl/en/publications/750b6908-eeda-485b-b9c1-1df37d25a65b
https://pure.eur.nl/en/publications/750b6908-eeda-485b-b9c1-1df37d25a65b
Autor:
Nicole R. Cunningham, Stephen G. Emerson, Ruben Land, Matthew Gross, Sophie Eiger, Jenni A. Punt, Russell Garrett, Shwetha Manjunath, Trevor Barlowe
Publikováno v:
Blood. 118:2339-2339
Abstract 2339 Recent studies have highlighted the importance of the NR4A nuclear receptor family (Nur77 (Nr4a1), Nurr1 (Nr4a3), Nor1 (Nr4a2)) in the regulation of hematopoiesis. In murine models, NR4A gene deficiencies lead to aberrant proliferation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b425c956855de244e8872c58f6af9301
https://doi.org/10.1182/blood.v118.21.2339.2339
https://doi.org/10.1182/blood.v118.21.2339.2339