Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Trevor B. Gill"'
Autor:
Donna J. Cross, Chloe G Cross, Satoshi Minoshima, Trevor B. Gill, Michael A. Silverman, Marcella M. Cline, David G. Cook, Bertrand R. Huber
Publikováno v:
Journal of Alzheimer's Disease. 83:379-394
Background: Microtubule stabilizing drugs, commonly used as anti-cancer therapeutics, have been proposed for treatment of Alzheimer’s disease (AD); however, many do not cross the blood-brain barrier. Objective: This research investigated if paclita
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a3dec6901a2c06e67e83797ba7dd97d
https://doi.org/10.3233/jad-210109
https://doi.org/10.3233/jad-210109
Publikováno v:
Neurobiology of aging. 36(3)
Defective brain insulin signaling contributes to the cognitive deficits in Alzheimer's disease (AD). Amyloid-beta oligomers (AβOs), the primary neurotoxin implicated in AD, downregulate insulin signaling by impairing protein kinase B/AKT, thereby ov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f56e8a2dd13415a0e17fa44cfe02987a
https://pubmed.ncbi.nlm.nih.gov/25543463
https://pubmed.ncbi.nlm.nih.gov/25543463