Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Trevor, Brasel"'
Autor:
Dylan M. Johnson, Terry Juelich, Lihong Zhang, Jennifer K. Smith, Birte K. Kalveram, David Perez, Jeanon Smith, Michael R. Grimes, Tania Garron, Maricela Torres, Shane Massey, Trevor Brasel, David W. C. Beasley, Alex N. Freiberg, Jason E. Comer
Publikováno v:
Viruses, Vol 16, Iss 7, p 1101 (2024)
Favipiravir is a ribonucleoside analogue that has been explored as a therapeutic for the treatment of Ebola Virus Disease (EVD). Promising data from rodent models has informed nonhuman primate trials, as well as evaluation in patients during the 2013
Externí odkaz:
https://doaj.org/article/930a651013754a5698d362b0dbc18049
Autor:
Jason E. Comer, Trevor Brasel, Shane Massey, David W. Beasley, Chris M. Cirimotich, Daniel C. Sanford, Ying-Liang Chou, Nancy A. Niemuth, Joseph Novak, Carol L. Sabourin, Michael Merchlinsky, James P. Long, Eric J. Stavale, Daniel N. Wolfe
Publikováno v:
Viruses, Vol 14, Iss 10, p 2291 (2022)
The Biomedical Advanced Research and Development Authority, part of the Administration for Strategic Preparedness and Response within the U.S. Department of Health and Human Services, recognizes that the evaluation of medical countermeasures under th
Externí odkaz:
https://doaj.org/article/c85b8d728e1144f385ab8e82d08e0696
Autor:
Conrad E Z Chan, Shirley G K Seah, De Hoe Chye, Shane Massey, Maricela Torres, Angeline P C Lim, Steven K K Wong, Jacklyn J Y Neo, Pui San Wong, Jie Hui Lim, Gary S L Loh, Dongling Wang, Jerome D Boyd-Kirkup, Siyu Guan, Dipti Thakkar, Guo Hui Teo, Kiren Purushotorman, Paul E Hutchinson, Barnaby E Young, Jenny G Low, Paul A MacAry, Hannes Hentze, Venkateshan S Prativadibhayankara, Kantharaj Ethirajulu, Jason E Comer, Chien-Te K Tseng, Alan D T Barrett, Piers J Ingram, Trevor Brasel, Brendon John Hanson
Publikováno v:
PLoS ONE, Vol 16, Iss 6, p e0253487 (2021)
Although SARS-CoV-2-neutralizing antibodies are promising therapeutics against COVID-19, little is known about their mechanism(s) of action or effective dosing windows. We report the generation and development of SC31, a potent SARS-CoV-2 neutralizin
Externí odkaz:
https://doaj.org/article/98d0e9238a8f44f8a516de81e7cb9d0e
Autor:
Nancy A Niemuth, Dawn Fallacara, Cheryl A Triplett, Sanjay M Tamrakar, Alisha Rajbhandari, Clint Florence, Lucy Ward, Anthony Griffiths, Ricardo Carrion, Yenny Goez-Gazi, Kendra J Alfson, Hilary M Staples, Trevor Brasel, Jason E Comer, Shane Massey, Jeanon Smith, Andrew Kocsis, Jake Lowry, Sara C Johnston, Aysegul Nalca, Arthur J Goff, Amy C Shurtleff, Margaret L Pitt, John Trefry, Michael P Fay
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0252874 (2021)
Filoviruses (Family Filoviridae genera Ebolavirus and Marburgvirus) are negative-stranded RNA viruses that cause severe health effects in humans and non-human primates, including death. Except in outbreak settings, vaccines and other medical counterm
Externí odkaz:
https://doaj.org/article/872942b1dcae494498eca02d622ed9e7
Autor:
Reid Rubsamen, Scott Burkholz, Christopher Massey, Trevor Brasel, Tom Hodge, Lu Wang, Charles Herst, Richard Carback, Paul Harris
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Cytokine release syndrome (CRS) is known to be a factor in morbidity and mortality associated with acute viral infections including those caused by filoviruses and coronaviruses. IL-6 has been implicated as a cytokine negatively associated with survi
Externí odkaz:
https://doaj.org/article/d17bf1e305ad49f5a7f4f702518576f0
Autor:
Olivier Escaffre, Terry L. Juelich, Natasha Neef, Shane Massey, Jeanon Smith, Trevor Brasel, Jennifer K. Smith, Birte Kalveram, Lihong Zhang, David Perez, Tetsuro Ikegami, Alexander N. Freiberg, Jason E. Comer
Publikováno v:
Viruses, Vol 13, Iss 7, p 1388 (2021)
Currently there is no FDA-licensed vaccine or therapeutic against Sudan ebolavirus (SUDV) infections. The largest ever reported 2014–2016 West Africa outbreak, as well as the 2021 outbreak in the Democratic Republic of Congo, highlight the critical
Externí odkaz:
https://doaj.org/article/b7e6ee05ac214387bcee0e49e5b0ebf3
Autor:
Dylan M. Johnson, Trevor Brasel, Shane Massey, Jeanon Smith, Tania Garron, Shannon Wallace, Xiaoying Yu, David W. Beasley, Jason E. Comer
Publikováno v:
Journal of Virology. 97
This study is the first to examine the Kikwit strain of EBOV, the most commonly used strain, in the gold-standard macaque model of infection. Additionally, this is the first description of the detection of virus in the vitreous fluid, an immune privi
Autor:
Christine A. Shaw, Allison August, Stephan Bart, Peta-Gay Jackson Booth, Conor Knightly, Trevor Brasel, Scott C. Weaver, HongHong Zhou, Lori Panther
Publikováno v:
Vaccine.
Autor:
Paul E. Harris, Trevor Brasel, Christopher Massey, C. V. Herst, Scott Burkholz, Peter Lloyd, Tikoes Blankenberg, Thomas M. Bey, Richard Carback, Thomas Hodge, Serban Ciotlos, Lu Wang, Jason E. Comer, Reid M. Rubsamen
Publikováno v:
Vaccines, Vol 9, Iss 5, p 520 (2021)
Background: Persistent transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has given rise to a COVID-19 pandemic. Several vaccines, conceived in 2020, that evoke protective spike antibody responses are being deployed in mass
Externí odkaz:
https://doaj.org/article/678fc80ad1ba43db995b78bda5058a94
Autor:
Yakun Liu, Tania M. Garron, Qing Chang, Zhengchen Su, Changcheng Zhou, Yuan Qiu, Eric C. Gong, Junying Zheng, Y. Whitney Yin, Thomas Ksiazek, Trevor Brasel, Yang Jin, Paul Boor, Jason E. Comer, Bin Gong
Publikováno v:
Pathogens, Vol 10, Iss 5, p 509 (2021)
The SARS-CoV-2 pandemic has inspired renewed interest in understanding the fundamental pathology of acute respiratory distress syndrome (ARDS) following infection. However, the pathogenesis of ARDS following SRAS-CoV-2 infection remains largely unkno
Externí odkaz:
https://doaj.org/article/3cd9e5867fb44056b7232fbd2bea5447