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Akademický článek

SGN-B7H4V, an investigational vedotin ADC directed to the immune checkpoint ligand B7-H4, shows promising activity in preclinical models.

Autor: Gray E; Seagen Inc, Bothell, Washington, USA egray@seagen.com., Ulrich M; Seagen Inc, Bothell, Washington, USA., Epp A; Seagen Inc, Bothell, Washington, USA., Younan P; Seagen Inc, Bothell, Washington, USA., Sahetya D; Seagen Inc, Bothell, Washington, USA., Hensley K; Seagen Inc, Bothell, Washington, USA., Allred S; Seagen Inc, Bothell, Washington, USA., Huang LY; Seagen Inc, Bothell, Washington, USA., Hahn J; Seagen Inc, Bothell, Washington, USA., Gahnberg K; Seagen Inc, Bothell, Washington, USA., Treuting PM; Seagen Inc, Bothell, Washington, USA., Trueblood ES; Seagen Inc, Bothell, Washington, USA., Gosink JJ; Seagen Inc, Bothell, Washington, USA., Thurman R; Seagen Inc, Bothell, Washington, USA., Wo S; Seagen Inc, Bothell, Washington, USA., Spahr K; Seagen Inc, Bothell, Washington, USA., Haass EJ; Seagen Inc, Bothell, Washington, USA., Snead K; Seagen Inc, Bothell, Washington, USA., Miller D; Seagen Inc, Bothell, Washington, USA., Padilla M; Seagen Inc, Bothell, Washington, USA., Smith AJ; Seagen Inc, Bothell, Washington, USA., Frantz C; Seagen Inc, Bothell, Washington, USA., Schrum JP; Seagen Inc, Bothell, Washington, USA., Nazarenko N; Seagen Inc, Bothell, Washington, USA., Gardai SJ; Seagen Inc, Bothell, Washington, USA.

Publikováno v: Journal for immunotherapy of cancer [J Immunother Cancer] 2023 Oct; Vol. 11 (10).

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Akademický článek

Acute renal injury from thrombotic microangiopathy associated with enteritis in New Zealand white rabbits.

Autor: Waggie KS; Department of Comparative Medicine, School of Medicine, University of Washington, Seattle, WA, USA., Snyder JM; Department of Comparative Medicine, School of Medicine, University of Washington, Seattle, WA, USA., Treuting PM; Department of Comparative Medicine, School of Medicine, University of Washington, Seattle, WA, USA.

Publikováno v: Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc [J Vet Diagn Invest] 2022 Sep; Vol. 34 (5), pp. 879-883. Date of Electronic Publication: 2022 Aug 10.

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Akademický článek

Effects of Stocking Density on Stress Response and Susceptibility to Infectious Hematopoietic Necrosis Virus in Rainbow Trout.

Autor: Klug JJ; Department of Comparative Medicine, University of Washington, Seattle, Washington., Treuting PM; Department of Comparative Medicine, University of Washington, Seattle, Washington., Sanders GE; Department of Comparative Medicine, University of Washington, Seattle, Washington., Winton JR; US Geological Survey, Western Fisheries Research Center, Seattle, Washington., Kurath G; US Geological Survey, Western Fisheries Research Center, Seattle, Washington.

Publikováno v: Journal of the American Association for Laboratory Animal Science : JAALAS [J Am Assoc Lab Anim Sci] 2021 Nov 01; Vol. 60 (6), pp. 637-645. Date of Electronic Publication: 2021 Sep 20.

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Akademický článek

Protective Effects of ALDH1A Enzyme Inhibition on Helicobacter -Induced Colitis in Smad3 ^-/- Mice are Associated with Altered α4ß7 Integrin Expression on Activated T Cells.

Autor: Seamons A; Department of Comparative Medicine, University of Washington, Seattle, WA 98195, USA., Haenisch M; Department of Comparative Medicine, University of Washington, Seattle, WA 98195, USA., Meeker S; Department of Comparative Medicine, University of Washington, Seattle, WA 98195, USA., Pershutkina O; Department of Comparative Medicine, University of Washington, Seattle, WA 98195, USA., Brabb T; Department of Comparative Medicine, University of Washington, Seattle, WA 98195, USA., Treuting PM; Department of Comparative Medicine, University of Washington, Seattle, WA 98195, USA., Paik J; Department of Comparative Medicine, University of Washington, Seattle, WA 98195, USA.

Publikováno v: Nutrients [Nutrients] 2020 Sep 24; Vol. 12 (10). Date of Electronic Publication: 2020 Sep 24.

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Akademický článek

PPARα exacerbates necroptosis, leading to increased mortality in postinfluenza bacterial superinfection.

Autor: Tam VC; Department of Microbiology and Immunology, Temple University, Philadelphia, PA 19140., Suen R; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA 98109., Treuting PM; Department of Comparative Medicine, University of Washington, Seattle, WA 98195., Armando A; Department of Chemistry and Biochemistry, School of Medicine, University of California San Diego, La Jolla, CA 92093.; Department of Pharmacology, School of Medicine, University of California San Diego, La Jolla, CA 92093., Lucarelli R; Department of Microbiology and Immunology, Temple University, Philadelphia, PA 19140., Gorrochotegui-Escalante N; Department of Microbiology and Immunology, Temple University, Philadelphia, PA 19140., Diercks AH; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA 98109., Quehenberger O; Department of Medicine, School of Medicine, University of California San Diego, La Jolla, CA 92093., Dennis EA; Department of Chemistry and Biochemistry, School of Medicine, University of California San Diego, La Jolla, CA 92093., Aderem A; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA 98109., Gold ES; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA 98109; elizabeth.gold@seattlechildrens.org.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Jul 07; Vol. 117 (27), pp. 15789-15798. Date of Electronic Publication: 2020 Jun 24.

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