Multi-faceted proteomic characterization of host protein complement of Rift Valley fever virus virions and identification of specific heat shock proteins, including HSP90, as important viral host factors.

Autor: Nuss JE; US Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America., Kehn-Hall K; School of Systems Biology, and National Center for Biodefense & Infectious Diseases, George Mason University, Manassas, Virginia, United States of America., Benedict A; School of Systems Biology, and National Center for Biodefense & Infectious Diseases, George Mason University, Manassas, Virginia, United States of America., Costantino J; US Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America., Ward M; US Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America., Peyser BD; US Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America., Retterer CJ; US Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America., Tressler LE; US Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America., Wanner LM; US Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America., McGovern HF; US Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America., Zaidi A; US Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America., Anthony SM; University of Texas Health Sciences Center, Houston, Texas, United States of America., Kota KP; US Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America., Bavari S; US Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America., Hakami RM; School of Systems Biology, and National Center for Biodefense & Infectious Diseases, George Mason University, Manassas, Virginia, United States of America.

Publikováno v: PloS one [PLoS One] 2014 May 08; Vol. 9 (5), pp. e93483. Date of Electronic Publication: 2014 May 08 (Print Publication: 2014).

The osmolyte trimethylamine N-oxide (TMAO) increases the proteolytic activity of botulinum neurotoxin light chains A, B, and E: implications for enhancing analytical assay sensitivity.

Autor: Nuss JE; US Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702 , USA., Wanner LM, Tressler LE, Bavari S

Publikováno v: Journal of biomolecular screening [J Biomol Screen] 2010 Sep; Vol. 15 (8), pp. 928-36. Date of Electronic Publication: 2010 Aug 18.

Three-dimensional database mining identifies a unique chemotype that unites structurally diverse botulinum neurotoxin serotype A inhibitors in a three-zone pharmacophore.

Autor: Hermone AR; Target Structure-Based Drug Discovery Group, SAIC-Frederick, Inc. National Cancer Institute at Frederick, P.O. Box B, Frederick, MD 21702, USA., Burnett JC, Nuss JE, Tressler LE, Nguyen TL, Solaja BA, Vennerstrom JL, Schmidt JJ, Wipf P, Bavari S, Gussio R

Publikováno v: ChemMedChem [ChemMedChem] 2008 Dec; Vol. 3 (12), pp. 1905-12.