An expanded evaluation of protein function prediction methods shows an improvement in accuracy

Autor: Jiang, Yuxiang, Oron, Tal Ronnen, Clark, Wyatt T, Bankapur, Asma R, D'Andrea, Daniel, Lepore, Rosalba, Funk, Christopher S, Kahanda, Indika, Verspoor, Karin M, Ben-Hur, Asa, Koo, Emily, Penfold-Brown, Duncan, Shasha, Dennis, Youngs, Noah, Bonneau, Richard, Lin, Alexandra, Sahraeian, Sayed ME, Martelli, Pier Luigi, Profiti, Giuseppe, Casadio, Rita, Cao, Renzhi, Zhong, Zhaolong, Cheng, Jianlin, Altenhoff, Adrian, Skunca, Nives, Dessimoz, Christophe, Dogan, Tunca, Hakala, Kai, Kaewphan, Suwisa, Mehryary, Farrokh, Salakoski, Tapio, Ginter, Filip, Fang, Hai, Smithers, Ben, Oates, Matt, Gough, Julian, Törönen, Petri, Koskinen, Patrik, Holm, Liisa, Chen, Ching-Tai, Hsu, Wen-Lian, Bryson, Kevin, Cozzetto, Domenico, Minneci, Federico, Jones, David T, Chapman, Samuel, C., Dukka B K., Khan, Ishita K, Kihara, Daisuke, Ofer, Dan, Rappoport, Nadav, Stern, Amos, Cibrian-Uhalte, Elena, Denny, Paul, Foulger, Rebecca E, Hieta, Reija, Legge, Duncan, Lovering, Ruth C, Magrane, Michele, Melidoni, Anna N, Mutowo-Meullenet, Prudence, Pichler, Klemens, Shypitsyna, Aleksandra, Li, Biao, Zakeri, Pooya, ElShal, Sarah, Tranchevent, Léon-Charles, Das, Sayoni, Dawson, Natalie L, Lee, David, Lees, Jonathan G, Sillitoe, Ian, Bhat, Prajwal, Nepusz, Tamás, Romero, Alfonso E, Sasidharan, Rajkumar, Yang, Haixuan, Paccanaro, Alberto, Gillis, Jesse, Sedeño-Cortés, Adriana E, Pavlidis, Paul, Feng, Shou, Cejuela, Juan M, Goldberg, Tatyana, Hamp, Tobias, Richter, Lothar, Salamov, Asaf, Gabaldon, Toni, Marcet-Houben, Marina, Supek, Fran, Gong, Qingtian, Ning, Wei, Zhou, Yuanpeng, Tian, Weidong, Falda, Marco, Fontana, Paolo, Lavezzo, Enrico, Toppo, Stefano, Ferrari, Carlo, Giollo, Manuel, Piovesan, Damiano, Tosatto, Silvio, del Pozo, Angela, Fernández, José M, Maietta, Paolo, Valencia, Alfonso, Tress, Michael L, Benso, Alfredo, Di Carlo, Stefano, Politano, Gianfranco, Savino, Alessandro, Rehman, Hafeez Ur, Re, Matteo, Mesiti, Marco, Valentini, Giorgio, Bargsten, Joachim W, van Dijk, Aalt DJ, Gemovic, Branislava, Glisic, Sanja, Perovic, Vladmir, Veljkovic, Veljko, Veljkovic, Nevena, Almeida-e-Silva, Danillo C, Vencio, Ricardo ZN, Sharan, Malvika, Vogel, Jörg, Kansakar, Lakesh, Zhang, Shanshan, Vucetic, Slobodan, Wang, Zheng, Sternberg, Michael JE, Wass, Mark N, Huntley, Rachael P, Martin, Maria J, O'Donovan, Claire, Robinson, Peter N, Moreau, Yves, Tramontano, Anna, Babbitt, Patricia C, Brenner, Steven E, Linial, Michal, Orengo, Christine A, Rost, Burkhard, Greene, Casey S, Mooney, Sean D, Friedberg, Iddo, Radivojac, Predrag

Background: The increasing volume and variety of genotypic and phenotypic data is a major defining characteristic of modern biomedical sciences. At the same time, the limitations in technology for generating data and the inherently stochastic nature

Externí odkaz: http://arxiv.org/abs/1601.00891

Lost in the WASH. The functional human WASH complex 1 gene is on chromosome 20

Autor: Cerdán-Vélez, Daniel, Tress, Michael L.

Publikováno v: bioRxiv

The WASH1 gene produces a protein that forms part of the developmentally important WASH complex. The WASH complex activates the Arp2/3 complex to initiate branched actin networks at the surface of endosomes. As a curiosity, the human reference gene s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4786fcec5442fd64d03cd85248599dcc
https://europepmc.org/articles/PMC10312774/

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

The Implications of Alternative Splicing in the ENCODE Protein Complement

Autor: Tress, Michael L., Martelli, Pier Luigi, Frankish, Adam, Reeves, Gabrielle A., Wesselink, Jan Jaap, Yeats, Corin, Olason, Páll Ísólfur, Albrecht, Mario, Hegyi, Hedi, Giorgetti, Alejandro, Raimondo, Domenico, Lagarde, Julien, Laskowski, Roman A., López, Gonzalo, Sadowski, Michael I., Watson, James D., Fariselli, Piero, Rossi, Ivan, Nagy, Alinda, Kai, Wang, Størling, Zenia, Orsini, Massimiliano, Assenov, Yassen, Blankenburg, Hagen, Huthmacher, Carola, Ramírez, Fidel, Schlicker, Andreas, Denoued, France, Jones, Phil, Kerrien, Samuel, Orchard, Sandra, Antonarakis, Stylianos E., Reymond, Alexandre, Birney, Ewan, Brunak, Søren, Casadio, Rita, Guigo, Roderic, Harrow, Jennifer, Hermjakob, Henning, Jones, David T., Lengauer, Thomas, Orengo, Christine A., Patthy, László, Thornton, Janet M., Tramontano, Anna, Valencia, Alfonso

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 2007 Mar . 104(13), 5495-5500.

Externí odkaz: https://www.jstor.org/stable/25427223

An analysis of tissue-specific alternative splicing at the protein level

Autor: Rodriguez, Jose Manuel, Pozo, Fernando, di Domenico, Tomas, Vazquez, Jesus, Tress, Michael, Tress, Michael L, Tress, Michael L.

Publikováno v: Repisalud
Instituto de Salud Carlos III (ISCIII)
PLoS Computational Biology
PLoS Computational Biology, Vol 16, Iss 10, p e1008287 (2020)

The role of alternative splicing is one of the great unanswered questions in cellular biology. There is strong evidence for alternative splicing at the transcript level, and transcriptomics experiments show that many splice events are tissue specific

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56f3f835a582bb8abc05759128d27673
http://hdl.handle.net/20.500.12105/11190