Anthracycline antibiotics and their derivatives, inhibitors of topoisomerase I

Autor: Alexander A. Shtil, Lyubov G. Dezhenkova, Olsuf'eva En, Preobrazhenskaia Mn, Teviashova An, Treshchalin Id

Publikováno v: Russian Journal of Bioorganic Chemistry. 34:387-389

The relationship between the structure of new semisynthetic derivatives of doxorubicin, daunorubicin, and carminomycin and their ability to inhibit topoisomerase 1 were studied. The new derivatives inhibit the activity of topoisomerase 1 at low conce

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https://doi.org/10.1134/s1068162008030230

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Discovery of Amphamide, a Drug Candidate for the Second Generation of Polyene Antibiotics.

Autor: Tevyashova AN; Gause Institute of New Antibiotics, 11 B. Pirogovskaya, Moscow, 199021, Russia.; D. Mendeleev University of Chemical Technology of Russia, 9 Miusskaya sq., Moscow, 125047, Russia., Bychkova EN; Gause Institute of New Antibiotics, 11 B. Pirogovskaya, Moscow, 199021, Russia., Solovieva SE; Gause Institute of New Antibiotics, 11 B. Pirogovskaya, Moscow, 199021, Russia., Zatonsky GV; Gause Institute of New Antibiotics, 11 B. Pirogovskaya, Moscow, 199021, Russia., Grammatikova NE; Gause Institute of New Antibiotics, 11 B. Pirogovskaya, Moscow, 199021, Russia., Isakova EB; Gause Institute of New Antibiotics, 11 B. Pirogovskaya, Moscow, 199021, Russia., Mirchink EP; Gause Institute of New Antibiotics, 11 B. Pirogovskaya, Moscow, 199021, Russia., Treshchalin ID; Gause Institute of New Antibiotics, 11 B. Pirogovskaya, Moscow, 199021, Russia., Pereverzeva ER; Gause Institute of New Antibiotics, 11 B. Pirogovskaya, Moscow, 199021, Russia., Bykov EE; Gause Institute of New Antibiotics, 11 B. Pirogovskaya, Moscow, 199021, Russia., Efimova SS; Institute of Cytology of the Russian Academy of Sciences, 4 Tikhoretsky ave., St. Petersburg, 194064, Russia., Ostroumova OS; Institute of Cytology of the Russian Academy of Sciences, 4 Tikhoretsky ave., St. Petersburg, 194064, Russia., Shchekotikhin AE; Gause Institute of New Antibiotics, 11 B. Pirogovskaya, Moscow, 199021, Russia.; D. Mendeleev University of Chemical Technology of Russia, 9 Miusskaya sq., Moscow, 125047, Russia.

Publikováno v: ACS infectious diseases [ACS Infect Dis] 2020 Aug 14; Vol. 6 (8), pp. 2029-2044. Date of Electronic Publication: 2020 Jul 22.

[Cytostatic-assisted myelosuppression using dicarbamin, an oral hematoprotector (experimental study)].

Autor: Treshchalin ID, Bodiagin DA, Pereverzeva ER, Treshchalin MI, Nebol'sin VE

Publikováno v: Voprosy onkologii [Vopr Onkol] 2009; Vol. 55 (6), pp. 769-74.

[Comparative analysis of in vitro antifungal activity and in vivo acute toxicity of the nystatin analogue S44HP produced via genetic engineering].

Autor: Treshchalin ID, Sletta H, Borgos SE, Pereverzeva EP, Voeĭkova TA, Ellingsen TE, Zotchev SB

Publikováno v: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] [Antibiot Khimioter] 2005; Vol. 50 (7), pp. 18-22.