Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Trent C Bjorndahl"'
Autor:
Beshay N Zordoky, Miranda M Sung, Justin Ezekowitz, Rupasri Mandal, Beomsoo Han, Trent C Bjorndahl, Souhaila Bouatra, Todd Anderson, Gavin Y Oudit, David S Wishart, Jason R B Dyck, Alberta HEART
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0124844 (2015)
Heart failure (HF) with preserved ejection fraction (HFpEF) is increasingly recognized as an important clinical entity. Preclinical studies have shown differences in the pathophysiology between HFpEF and HF with reduced ejection fraction (HFrEF). The
Externí odkaz:
https://doaj.org/article/5691576af65d4fb18a7bd3345080df69
Autor:
Siamak Ravanbakhsh, Philip Liu, Trent C Bjorndahl, Rupasri Mandal, Jason R Grant, Michael Wilson, Roman Eisner, Igor Sinelnikov, Xiaoyu Hu, Claudio Luchinat, Russell Greiner, David S Wishart
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132873 (2015)
Externí odkaz:
https://doaj.org/article/b40fdace377a4936976fa230c9fca873
Autor:
Siamak Ravanbakhsh, Philip Liu, Trent C Bjorndahl, Rupasri Mandal, Jason R Grant, Michael Wilson, Roman Eisner, Igor Sinelnikov, Xiaoyu Hu, Claudio Luchinat, Russell Greiner, David S Wishart
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0124219 (2015)
Many diseases cause significant changes to the concentrations of small molecules (a.k.a. metabolites) that appear in a person's biofluids, which means such diseases can often be readily detected from a person's "metabolic profile"-i.e., the list of c
Externí odkaz:
https://doaj.org/article/029146e4dc8a42e18d73bf579659789c
Autor:
Souhaila Bouatra, Farid Aziat, Rupasri Mandal, An Chi Guo, Michael R Wilson, Craig Knox, Trent C Bjorndahl, Ramanarayan Krishnamurthy, Fozia Saleem, Philip Liu, Zerihun T Dame, Jenna Poelzer, Jessica Huynh, Faizath S Yallou, Nick Psychogios, Edison Dong, Ralf Bogumil, Cornelia Roehring, David S Wishart
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e73076 (2013)
Urine has long been a "favored" biofluid among metabolomics researchers. It is sterile, easy-to-obtain in large volumes, largely free from interfering proteins or lipids and chemically complex. However, this chemical complexity has also made urine a
Externí odkaz:
https://doaj.org/article/7c98e2038b39406aab29f536252abb90
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1866:982-988
Prion (PrP) diseases are neurodegenerative diseases characterized by the formation of β-sheet rich, insoluble and protease resistant protein deposits (called PrPSc) that occur throughout the brain. Formation of synthetic or in vitro PrPSc can occur
Autor:
Trent C. Bjorndahl, Khajamohiddin Syed, David S. Wishart, Michael A. Joyce, Nataraj Sekhar Pagadala, Abdolamir Landi
Publikováno v:
Bioorganic & Medicinal Chemistry. 25:5875-5888
Prion diseases are fatal neurodegenerative disorders of the central nervous system characterized by the accumulation of a protease resistant form (PrPSc) of the cellular prion protein (PrPC) in the brain. Two types of cellular prion (PrPC) compounds
Publikováno v:
MOJ Drug Design Development & Therapy. 2
Epigallocatechin gallate EGCG is a naturally occurring alkaloid found in green tea It has been shown to bind with nanomolar affinity to the monomeric prion protein and induce conformational instability A better understanding of the specific molecular
Autor:
Carol L. Ladner-Keay, Trent C. Bjorndahl, Li Ross, Lun Zhang, Rolando Perez-Pineiro, Neil R. Cashman, David S. Wishart
Publikováno v:
Prion. 12(5-6)
Prion diseases are caused by the conversion of normal cellular prion proteins (PrP) into lethal prion aggregates. These prion aggregates are composed of proteinase K (PK) resistant fibrils and comparatively PK-sensitive oligomers. Currently there are
Autor:
David S. Wishart, A. E. Somerset, A. W. L. Bayci, Onur Turkoglu, Dustin Baker, Stewart F. Graham, Ray O. Bahado-Singh, Beomsoo Han, Zachary Hothem, Trent C. Bjorndahl, R. Mandal, Rose E. Callahan, Richard Keidan
Publikováno v:
Metabolomics. 14
Melanoma is a highly aggressive malignancy and is currently one of the fastest growing cancers worldwide. While early stage (I and II) disease is highly curable with excellent prognosis, mortality rates rise dramatically after distant spread. We soug
Autor:
Amna Zeb, Liang Li, David S. Wishart, Edison Dong, Onur Turkoglu, Dev Maulik, Beomsoo Han, Chiao-Li Tseng, Ray O. Bahado-Singh, Kypros H. Nicolaides, Mark Redman, Trent C. Bjorndahl, Nan Wang, R. Mandal, Argyro Syngelaki
Publikováno v:
The journal of maternal-fetalneonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians. 32(20)
Background: Stillbirth remains a major problem in both developing and developed countries. Omics evaluation of stillbirth has been highlighted as a top research priority. Objective: To identify new putative first-trimester biomarkers in maternal seru