Zobrazeno 1 - 10
of 711
pro vyhledávání: '"Trembleau, A."'
Autor:
Lamya H. Al-Wahaibi, Hesham A. Abou-Zied, Mostafa H. Abdelrahman, Martha M. Morcoss, Laurent Trembleau, Bahaa G. M. Youssif, Stefan Bräse
Publikováno v:
Frontiers in Chemistry, Vol 12 (2024)
The present study details the design, synthesis, and bio-evaluation of indoles 3–16 as dual inhibitors of aromatase and inducible nitric oxide synthase (iNOS)with antiproliferative activity. The study evaluates the antiproliferative efficacy of 3
Externí odkaz:
https://doaj.org/article/39a0c8a8c6484f1a92f6ac096afce3c5
Autor:
Salima Messaoudi, Ada Allam, Julie Stoufflet, Theo Paillard, Anaïs Le Ven, Coralie Fouquet, Mohamed Doulazmi, Alain Trembleau, Isabelle Caille
Publikováno v:
eLife, Vol 12 (2024)
The fragile X syndrome (FXS) represents the most prevalent form of inherited intellectual disability and is the first monogenic cause of autism spectrum disorder. FXS results from the absence of the RNA-binding protein FMRP (fragile X messenger ribon
Externí odkaz:
https://doaj.org/article/13fa9b263153445990b54ed25e7201d9
Autor:
Lamya H. Al-Wahaibi, Anber F. Mohammed, Fatema El-Zahraa S. Abdel Rahman, Mostafa H. Abdelrahman, Xuyuan Gu, Laurent Trembleau, Bahaa G. M. Youssif
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
A new series of indole-2-carboxamides 5a-g, 6a-f and pyrido[3,4-b]indol-1-ones 7a and 7b have been developed as new antiproliferative agents that target both wild and mutant type EGFR. The antiproliferative effect of the new compounds was studied. 5c
Externí odkaz:
https://doaj.org/article/ad0d6b80431c4610aa5b365ed3465666
Autor:
Breau, Marie Anne, Trembleau, Alain
Publikováno v:
In Seminars in Cell and Developmental Biology 15 May 2023 140:72-81
Akademický článek
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Autor:
Shan Wang, Sixing Lin, Qing Fang, Roland Gyampoh, Zhou Lu, Yingli Gao, David J. Clarke, Kewen Wu, Laurent Trembleau, Yi Yu, Kwaku Kyeremeh, Bruce F. Milne, Jioji Tabudravu, Hai Deng
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
The chemical diversity of peptides from ribosomal origin is a growing field of research. Here, the authors report the discovery, genomic and biosynthetic investigations of kintamdin, a ribosomally synthesized and post-translationally modified peptide
Externí odkaz:
https://doaj.org/article/8b57a4ca631948b589837ff094434bec
Autor:
Claudia Corrò, Nicolas C. Buchs, Matthieu Tihy, André Durham-Faivre, Philippe Bichard, Jean-Louis Frossard, Giacomo Puppa, Thomas McKee, Arnaud Roth, Thomas Zilli, Christelle Trembleau, Mariagrazia Di Marco, Valérie Dutoit, Pierre-Yves Dietrich, Frédéric Ris, Thibaud Koessler
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-8 (2022)
Abstract Background Reshaping the tumor microenvironment by novel immunotherapies represents a key strategy to improve cancer treatment. Nevertheless, responsiveness to these treatments is often correlated with the extent of T cell infiltration at th
Externí odkaz:
https://doaj.org/article/d7cd6151137d4ba7adddbcf2d6d73b80
Autor:
Gomaa, Hesham A.M., Shaker, Mohamed E., Alzarea, Sami I., Hendawy, O.M., Mohamed, Fatma A.M., Gouda, Ahmed M., Ali, Asmaa T., Morcoss, Martha M., Abdelrahman, Mostafa H., Trembleau, Laurent, Youssif, Bahaa G.M.
Publikováno v:
In Bioorganic Chemistry March 2022 120
Akademický článek
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Autor:
Al-Wahaibi, Lamya H., Mostafa, Ahmed, Mostafa, Yaser A., Abou-Ghadir, Ola F., Abdelazeem, Ahmed H., Gouda, Ahmed M., Kutkat, Omnia, Abo Shama, Noura M., Shehata, Mahmoud, Gomaa, Hesham A.M., Abdelrahman, Mostafa H., Mohamed, Fatma A.M., Gu, Xuyuan, Ali, Mohamed A., Trembleau, Laurent, Youssif, Bahaa G.M.
Publikováno v:
In Bioorganic Chemistry November 2021 116