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Dietary exposure to a low dose of pesticides alone or as a mixture: The biological metabolic fingerprint and impact on hematopoiesis

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Publikováno v: In Toxicology 7 June 2013 308:74-87

Hepatocyte-specific deletion of Pparα promotes NAFLD in the context of obesity

Autor: Régnier, M., Polizzi, A., Smati, S., Lukowicz, C., Fougerat, A., Lippi, Y., Fouché, E., Lasserre, F., Naylies, C., Bétoulières, C., Barquissau, V., Mouisel, E., Bertrand-Michel, J., Batut, A., Saati, T.A., Canlet, C., Tremblay-Franco, M., Ellero-Simatos, S., Langin, D., Postic, C., Wahli, W., Loiseau, N., Guillou, H., Montagner, A.

Publikováno v: Scientific Reports
Scientific Reports, 2020, 10 (1), pp.6489. ⟨10.1038/s41598-020-63579-3⟩
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Scientific Reports, Nature Publishing Group, 2020, 10 (1), pp.6489. ⟨10.1038/s41598-020-63579-3⟩
Scientific reports, vol. 10, no. 1, pp. 6489

Peroxisome proliferator activated receptor α (PPARα) acts as a fatty acid sensor to orchestrate the transcription of genes coding for rate-limiting enzymes required for lipid oxidation in hepatocytes. Mice only lacking Pparα in hepatocytes spontan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::49786ed8db08fd7baa1ce2888766837d
https://hdl.handle.net/10356/144951

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