Zobrazeno 1 - 10
of 6 370
pro vyhledávání: '"Tregs"'
Autor:
Yufeng Shang, Guopeng Chen, Li Liu, Ruiyang Pan, Xinqi Li, Hui Shen, Yuxin Tan, Linlu Ma, Xiqin Tong, Weida Wang, Xiaoqin Chen, Zhongjun Xia, Xiaoyan Liu, Fuling Zhou
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-14 (2024)
Abstract At present, the characteristics of double-hit multiple myeloma (DHMM) are unknown. We retrospectively analyzed the clinical data from 433 new diagnosed MM patients and found that DHMM have a higher β2-MG level and percentage of bone marrow
Externí odkaz:
https://doaj.org/article/79c965582c8b4c9da66af54724a3133a
Autor:
Zhenfeng Shi, Wenjing Pu, Min Li, Mierzhayiti Aihemaitijiang, Shuo Li, Xiaoan Zhang, Bide Liu, Min Sun, Jiuzhi Li, Zhiwei Li
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-16 (2024)
Abstract Background Docetaxel (DTX) resistance attenuates anti-tumor effects of DTX on prostate cancer (mCRPC) and drug resistance was related to Treg expansion in tumors. ZNF667-AS1 played a suppressing role in various tumors and tumor-derived exoso
Externí odkaz:
https://doaj.org/article/e8f7f4dba0714647974c95d81fe530ae
Publikováno v:
BMC Pediatrics, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Background Congenital cytomegalovirus (cCMV) infection can lead to a range of adverse outcomes. The majority of cCMV neonates with clinical symptoms are infected postnatally; however, established cases of intrauterine infection are uncommon,
Externí odkaz:
https://doaj.org/article/2614ec6330ad4025b20195345af3f59a
Autor:
Esraa Adel Mahmoud Mohamed Atia, Sanaa Abd Elmaged Sammour, Eman Abdel-Salam Ibrahim, Hoda Hassan Abou Gabal, Shimaa Abdelraouf Elgohary
Publikováno v:
The Egyptian Journal of Otolaryngology, Vol 40, Iss 1, Pp 1-11 (2024)
Abstract Background Glycoprotein A repetitions predominant (GARP) is a novel transmembrane protein highly expressed on the surface of regulatory T cells (Tregs), which are a subset of immunosuppressive T lymphocytes that play a major role in inhibiti
Externí odkaz:
https://doaj.org/article/365cf23912ed45cbaba9c07a93e11791
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-13 (2024)
Abstract Background Chronic obstructive pulmonary disease (COPD) is a widespread respiratory disease. This study examines extracellular vesicles (EVs) and proteins contained in EVs in COPD. Methods Blood samples were collected from 40 COPD patients a
Externí odkaz:
https://doaj.org/article/70c58cf280074c9c941c5ae5b9e895b1
Autor:
Jie Sun, Songli Shi, Chao Sun, Jiangping Wang, Xiaohui Yang, Zhengduo Yang, Jing Xu, Shiwu Zhang
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract Background Gene methylation and the immune-related tumor microenvironment (TME) are highly correlated in tumor progression and therapeutic efficacy. Although both of them can be used to predict the clinical outcomes of colorectal cancer (CRC
Externí odkaz:
https://doaj.org/article/692db410c9ef42ea85f00db801282232
Autor:
T. V. Radygina, O. V. Kurbatova, D. G. Kuptsova, S. V. Petrichuk, A. P. Fisenko, G. B. Movsisyan, L. M. Abdullaeva, A. S. Potapov, N. N. Murashkin, D. V. Parakhina
Publikováno v:
Медицинская иммунология, Vol 26, Iss 5, Pp 1017-1024 (2024)
In recent decades, there has been an increase in the incidence of autoimmune diseases (AID) among adults and children. The immunopathogenesis of AID is based on an imbalance between autoaggressive and regulatory cells (Tregs), which is regulated by m
Externí odkaz:
https://doaj.org/article/f9fa92cf4e324fccb65e2da803acd47a
Autor:
Zhaokai Zhou, Jiaxin Xu, Shutong Liu, Yingying Lv, Ruiqi Zhang, Xing Zhou, Yuyuan Zhang, Siyuan Weng, Hui Xu, Yuhao Ba, Anning Zuo, Xinwei Han, Zaoqu Liu
Publikováno v:
Biomarker Research, Vol 12, Iss 1, Pp 1-24 (2024)
Abstract Immunotherapy has shown promising anti-tumor effects across various tumors, yet it encounters challenges from the inhibitory tumor immune microenvironment (TIME). Infiltrating regulatory T cells (Tregs) are important contributors to immunosu
Externí odkaz:
https://doaj.org/article/3a9addb8e0234d0c8fd66f93bda6e9d6
Publikováno v:
Expert Review of Vaccines, Vol 23, Iss 1, Pp 812-829 (2024)
Introduction Cancer vaccines stimulate the activation of specific humoral and cellular adaptive responses against cancer cells.Antibodies generated post vaccination can be isolated and further selected to develop highly specific and potent monoclonal
Externí odkaz:
https://doaj.org/article/1f18e28cebf54c5d90d36e6bdae7d26f
Autor:
Amandda Évelin Silva-Carvalho, Elizabete Cristina Iseke Bispo, Ingrid Gracielle Martins da Silva, José Raimundo Correa, Juliana Lott Carvalho, Guilherme Martins Gelfuso, Felipe Saldanha-Araujo
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Ibrutinib (IB) is a tyrosine kinase inhibitor (TKI) that has immunomodulatory action and can be used as second-line therapy for steroid-refractory or steroid-resistant chronic Graft versus Host Disease (cGVHD). Mesenchymal stromal cells (MSC
Externí odkaz:
https://doaj.org/article/5f9d2e0d3db4484b947ab3deb0834acc