Výsledky vyhledávání - "Tregoning, JS"

Group B Streptococcus (GBS) colonization is dynamic over time, whilst GBS capsular polysaccharides-specific antibody remains stable

Autor: Haeusler, IL, Daniel, O, Isitt, C, Watts, R, Cantrell, L, Feng, S, Cochet, M, Salloum, M, Ikram, S, Hayter, E, Lim, S, Hall, T, Athaide, S, Cosgrove, CA, Tregoning, JS, Le Doare, K

Publikováno v: Clinical and Experimental Immunology. 209:188-200

Group B Streptococcus (GBS) is a leading cause of adverse pregnancy outcomes due to invasive infection. This study investigated longitudinal variation in GBS rectovaginal colonization, serum and vaginal GBS capsular polysaccharide (CPS)-specific anti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f66552981f49f84a9ecc3caf9296ed5f
https://doi.org/10.1093/cei/uxac066

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Interferon-induced Transmembrane Protein 1 restricts replication of virus that enter cells via the plasma membrane

Autor: Smith, SE, Busse, DC, Binter, Š, Weston, S, Diaz Soria, C, Laksono, BM, Clare, S, Van Nieuwkoop, S, Van den Hoogen, BG, Clement, M, Marsden, M, Humphreys, IR, Marsh, M, De Swart, RL, Wash, RS, Tregoning, JS, Kellam, P

The acute antiviral response is mediated by a family of interferon-stimulated genes (ISGs), providing cell-intrinsic immunity. Mutations in genes encoding these proteins are often associated with increased susceptibility to viral infections. One fami

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::a96c25810a3018fb5a7f7f0ee6b26638
https://orca.cardiff.ac.uk/id/eprint/118166/7/e02003-18.full.pdf

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The impact of an updated pandemic H1N1 strain on shedding and immunogenicity to Russian-backbone live attenuated influenza vaccine among children in The Gambia: an open-label, observational, phase 4 study

Autor: Lindsey, BB, Singanayagam, A, Tregoning, JS, De Silva, T, Barclay, W

Background: Poor efficacy and effectiveness of thepandemic H1N1 (pH1N1) component inlive attenuated influenza vaccine (LAIV)has been demonstrated in several studies.The reasons for this are unclear, butmay be due toimpairedreplicative fitness of pH1N

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1032::b6e5b99953abb9b171af044e99c78806
http://hdl.handle.net/10044/1/68667

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The impact of timing of maternal influenza immunization on infant antibody levels at birth

Autor: Zhong, Z, Haltalli, M, Holder, B, Rice, T, Donaldson, B, O'Driscoll, M, Le-Doare, K, Kampmann, B, Tregoning, JS

Pregnant women and infants are at an increased risk of severe disease after influenza infection. Maternal immunization is a potent tool to protect both these at-risk groups. While the primary aim of maternal influenza vaccination is to protect the mo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::1e4c306a1bc640f356c2be62fc2a2538

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Role of airway glucose in bacterial infections in chronic obstructive pulmonary disease

Publikováno v: 823.e6

Background Patients with chronic obstructive pulmonary disease (COPD) have increased susceptibility to respiratory tract infection, which contributes to disease progression and mortality, but mechanisms of increased susceptibility to infection remain

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1032::7cacca7b75319ee598561c063cf76b24
http://hdl.handle.net/10044/1/55776

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Airway T cells protect against RSV infection in the absence of antibody

Autor: Kinnear, E, Lambert, L, McDonald, JU, Cheeseman, HM, Caproni, LJ, Tregoning, JS

Tissue resident memory T (Trm) cells act as sentinels and early responders to infection. Respiratory syncytial virus (RSV)-specific Trm cells have been detected in the lungs after human RSV infection, but whether they have a protective role is unknow

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1032::f4c5ec3a8b4913e21ba395a8b75250ce
http://hdl.handle.net/10044/1/49273

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Increased airway glucose increases airway bacterial load in hyperglycaemia

Autor: Holmes, AH, Gill, SK, Hui, K, Farne, H, Garnett, JP, Baines, DL, Moore, LSP, Filloux, A, Tregoning, JS

Publikováno v: Scientific Reports

Diabetes is associated with increased frequency of hospitalization due to bacterial lung infection. We hypothesize that increased airway glucose caused by hyperglycaemia leads to increased bacterial loads. In critical care patients, we observed that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::0f9ac42cfac66d6dccc1286f17f32a6a
https://openaccess.sgul.ac.uk/id/eprint/108100/12/srep_27636.pdf

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A Multi-Component Prime-Boost Vaccination Regimen with a Consensus MOMP Antigen Enhances Chlamydia trachomatis Clearance

Autor: Badamchi-Zadeh, A, McKay, PF, Korber, BT, Barinaga, G, Walters, AA, Nunes, A, Gomes, JP, Follman, F, Tregoning, JS, Shattock, RJ

Publikováno v: Frontiers in Immunology, Vol 7 (2016)
Frontiers in Immunology

The Supplementary Material for this article can be found online at http://journal.frontiersin.org/article/10.3389/fimmu.2016.00162 BACKGROUND: A vaccine for Chlamydia trachomatis is of urgent medical need. We explored bioinformatic approaches to gene

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::8a07fbf2504fd92ce226c86478388611

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