Zobrazeno 1 - 10
of 1 795
pro vyhledávání: '"Treg cell"'
Autor:
Sun Ryu, Jintao Zhang, Roli Simoes, Xuemei Liu, Zhaohua Guo, Li Feng, Jacqueline Unsinger, Richard S. Hotchkiss, Yu-Qing Cao
Publikováno v:
The Journal of Headache and Pain, Vol 25, Iss 1, Pp 1-19 (2024)
Abstract Background Medication overuse headache (MOH) is the most common secondary headache disorder, resulting from chronic and excessive use of medication to treat headaches, for example, sumatriptan. In a recent study, we have shown that the perip
Externí odkaz:
https://doaj.org/article/0afc7094512b452f9250ba1226d66939
Autor:
Ling Chen, Yanru Xiang, Shirong Zhong, Yinglin Wu, Jiaqi Liu, Yan Wu, Zhizhi Wang, Guodong Huang
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 27, Iss 10, Pp 1276-1283 (2024)
Objective(s): Ulcerative colitis (UC) is a commonly recurrent inflammatory bowel disease. T helper 17 (Th17)/regulatory T (Treg) cell balance plays an essential role in UC progression. However, it is unknown whether curcumin chitosan microspheres (CC
Externí odkaz:
https://doaj.org/article/076e5e8e91ee49c9a0e8b1ab32221275
Autor:
Asami Suto, Takeo Minaguchi, Nan Qi, Kaoru Fujieda, Hiroya Itagaki, Yuri Tenjimbayashi, Ayumi Shikama, Nobutaka Tasaka, Azusa Akiyama, Sari Nakao, Chigusa Nakahashi-Oda, Yusuke Kobayashi, Akira Shibuya, Toyomi Satoh
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Regulatory T (Treg) cells reportedly play crucial roles in tumor angiogenesis as well as antitumor immunity. In order to explore their therapeutic potential, we investigated the precise prognostic impact of Treg markers in endomet
Externí odkaz:
https://doaj.org/article/6f42ba3886614c63a495397bd9f88619
Autor:
Geraldo Rubens R. Freitas, Maria da Luz Fernandes, Fabiana Agena, Francine B. C. Lemos, Flavio J. de Paula, Verônica Coelho, Elias David-Neto, Nelson Z. Galante
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundDespite the growing number of elderly kidney transplant (Ktx) recipients, few studies have examined the effects of immunosuppression on their lymphocyte profiles.MethodsWe evaluated the early conversion from mycophenolate sodium (MPS) to ev
Externí odkaz:
https://doaj.org/article/a105b66bc86b4e9b903eaf782335681d
Autor:
Dimitri Kakabadse, Dawei Chen, Sigal Fishman, Hadas Weinstein-Marom, Joanne Davies, Li Wen, Gideon Gross, F. Susan Wong
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionIn this study, we report a novel therapeutic approach redirecting antigen-specific CD4+ T cells recognizing a hybrid insulin peptide (BDC2.5 T cell receptor (TCR) transgenic CD4+ T cells) to attract and suppress islet-specific CD8+ T cell
Externí odkaz:
https://doaj.org/article/761b56308e79419ba5d4331c899df090
Autor:
Yuqiu Ge, Zhongtang Jia, Shiting Zhao, WenChao Zhang, Xian Shi, Ruijin Xie, Yan Gong, Jixiang Sheng, Rob J. van 't Hof, Jiatao Yang, Chunqing Han, Xiping Hu, Yafeng Wang, Yu Wu, Chunping Li, Miaomiao Wang
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 283, Iss , Pp 116943- (2024)
Lead (Pb) is an environmentally widespread bone toxic pollutant, contributes to the development of osteoporosis. Butyric acid, mainly produced by the fermentation of indigestible dietary fiber by gut microbiota, plays a pivotal role in the maintenanc
Externí odkaz:
https://doaj.org/article/1fb8090efa7346bbbc49d0f9ff19a6c7
Autor:
Dohnke, Sebastian, Moehser, Stephanie, Surnov, Alexey, Kurth, Thomas, Jessberger, Rolf, Kretschmer, Karsten, Garbe, Annette I.
In T cells, processes such as migration and immunological synapse formation are accompanied by the dynamic reorganization of the actin cytoskeleton, which has been suggested to be mediated by regulators of RhoGTPases and by F-actin bundlers. SWAP-70
Externí odkaz:
https://tud.qucosa.de/id/qucosa%3A91929
https://tud.qucosa.de/api/qucosa%3A91929/attachment/ATT-0/
https://tud.qucosa.de/api/qucosa%3A91929/attachment/ATT-0/
Autor:
Xiyu Song, Ruo Chen, Jiaxin Li, Yumeng Zhu, Jianhua Jiao, Hongjiao Liu, Zhinan Chen, Jiejie Geng
Publikováno v:
Pharmacological Research, Vol 206, Iss , Pp 107297- (2024)
Regulatory T (Treg) cells play a key role in maintaining immune tolerance and tissue homeostasis. However, in some disease microenvironments, Treg cells exhibit fragility, which manifests as preserved FoxP3 expression accompanied by inflammation and
Externí odkaz:
https://doaj.org/article/9b7d3264a08e493f92b296da27efd0ed
Autor:
Lanjiao Li, Jichun Chen, Zhenyan Wang, Yan Xu, Hao Yao, Wulong Lei, Xiyuan Zhou, Minming Zheng
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionThis study examined the impact of 5’-(N- ethylcarboxamido)adenosine (NECA) in the peripheral blood of healthy individuals, those with diabetes mellitus, diabetic retinopathy (DR), and C57BL/6 mice, both in vivo and in vitro.MethodsEnzym
Externí odkaz:
https://doaj.org/article/1a6a9a72bd0646e69e15df914eab2b18
Autor:
Pravin Yeapuri, Jatin Machhi, Yaman Lu, Mai Mohamed Abdelmoaty, Rana Kadry, Milankumar Patel, Shaurav Bhattarai, Eugene Lu, Krista L. Namminga, Katherine E. Olson, Emma G. Foster, R. Lee Mosley, Howard E. Gendelman
Publikováno v:
Molecular Neurodegeneration, Vol 18, Iss 1, Pp 1-22 (2023)
Abstract Background Regulatory T cells (Tregs) maintain immune tolerance. While Treg-mediated neuroprotective activities are now well-accepted, the lack of defined antigen specificity limits their therapeutic potential. This is notable for neurodegen
Externí odkaz:
https://doaj.org/article/e41efd3b0d7a4a99bcf11d2d1852d2b7