Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Treg, regulatory T cells"'
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Regulatory T (Treg) cells are garnering increased attention in research related to autoimmune diseases, including rheumatoid arthritis (RA). They play an essential role in the maintenance of immune homeostasis by restricting effector T cell activity.
Externí odkaz:
https://doaj.org/article/89634c9a00084e9c8784d5f2a61ccf07
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
T regulatory cells suppress a variety of immune responses to self-antigens and play a role in peripheral tolerance maintenance by limiting autoimmune disorders, and other pathological immune responses such as limiting immune reactivity to oncoprotein
Externí odkaz:
https://doaj.org/article/80e14b271ae04d16998a0ca019e9578e
Autor:
Alice Bertaina, Maria Grazia Roncarolo
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Allogeneic hematopoietic stem cell transplantation (HSCT) is a curative therapeutic option for a wide range of immune and hematologic malignant and non-malignant disorders. Once transplanted, allogeneic cells have to support myeloid repopulation and
Externí odkaz:
https://doaj.org/article/f0659acc44c94dd2a899ccb3dd5ef73a
Autor:
Iñaki F. Trocóniz, Juan Jose Perez-Ruixo, Xavier Woot de Trixhe, Eduardo Asín-Prieto, Kim Stuyckens, Zinnia P. Parra-Guillen, José David Gómez Mantilla, Joris Vandenbossche
Publikováno v:
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 4997-5007 (2021)
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 4997-5007 (2021)
Graphical abstract
Highlights • Mechanistic model characterizing acute immune response and HBV system interactions. • Key role of the cellular and regulatory response triggering hepatitis B chronicity. • Modelling framework to easily incor
Highlights • Mechanistic model characterizing acute immune response and HBV system interactions. • Key role of the cellular and regulatory response triggering hepatitis B chronicity. • Modelling framework to easily incor
Autor:
Christine P. Petersen, Kevin A. Bockerstett, Richard J. DiPaolo, Christine N. Noto, Ryan M. Teague, Lindsey M. Kuehm, Eric L. Ford, Jason C. Mills, James R. Goldenring, Chun Fung Wong
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 3, Pp 561-579 (2020)
Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 3, Pp 561-579 (2020)
Background & Aims The association between chronic inflammation and gastric carcinogenesis is well established, but it is not clear how immune cells and cytokines regulate this process. We investigated the role of interleukin 27 (IL27) in the developm
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Frontiers in Immunology
T regulatory cells suppress a variety of immune responses to self-antigens and play a role in peripheral tolerance maintenance by limiting autoimmune disorders, and other pathological immune responses such as limiting immune reactivity to oncoprotein
Autor:
Elena Giacomini, Enrico Garaci, Jing Zhang, Martina Severa, Michael Chopp, Marilena P. Etna, Eliana M. Coccia, Fabiana Rizzo, Melania Cruciani
Publikováno v:
Multiple Sclerosis and Related Disorders
Highlights • Thymosins are thymic hormone-like peptides that can mediate immune and non-immune physiological processes. • Thymosin-α1 (Tα1) displays powerful pleiotropic activities by promoting anti-inflammatory and regulatory milieu in differe
Autor:
Ryo Aoki, Toshiaki Teratani, Mari Mochizuki Arai, Kentaro Miyamoto, Yohei Mikami, Shinta Mizuno, Yosuke Harada, Ena Nomura, Takanori Kanai, Tomohisa Sujino, Hiroki Kiyohara, Makoto Naganuma, Yuzo Koda, Tadakazu Hisamatsu
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 1, Pp 135-156 (2019)
Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 1, Pp 135-156 (2019)
Background & Aims Psoriasis and inflammatory bowel disease (IBD) are both chronic inflammatory diseases occurring in the skin and gut, respectively. It is well established that psoriasis and IBD have high concordance rates, and similar changes in imm
Autor:
Kendra K. Bence, William P. Esler
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
The prevalence and diagnosis of nonalcoholic fatty liver disease (NAFLD) is on the rise worldwide and currently has no FDA-approved pharmacotherapy. The increase in disease burden of NAFLD and a more severe form of this progressive liver disease, non
Autor:
Vera Maria Morsch, Karine Paula Reichert, Milagros Fanny Vera Castro, Naiara Stefanello, Vanessa Valéria Miron, Andréia Machado Cardoso, Maria Rosa Chitolina Schetinger, Charles Elias Assmann, Nathieli B. Bottari
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 137, Iss, Pp 111273-(2021)
Biomedicine & Pharmacotherapy
Biomedicine & Pharmacotherapy
Graphical abstract
Highlights • The coexistence of diabetes and hypertension represents a major risk factor for the onset of cardiovascular problems. • The purinergic signaling pathway constitutes a ubiquitous system of cell–cell communica
Highlights • The coexistence of diabetes and hypertension represents a major risk factor for the onset of cardiovascular problems. • The purinergic signaling pathway constitutes a ubiquitous system of cell–cell communica