Zobrazeno 1 - 10
of 331
pro vyhledávání: '"Treg, Regulatory T"'
Autor:
Xiangni Wu, Pin-I Chen, Robert L. Whitener, Matthew S. MacDougall, Vy M. N. Coykendall, Hao Yan, Yong Bin Kim, William Harper, Shiva Pathak, Bettina P. Iliopoulou, Allison Hestor, Diane C. Saunders, Erick Spears, Jean Sévigny, David M. Maahs, Marina Basina, Seth A. Sharp, Anna L. Gloyn, Alvin C. Powers, Seung K. Kim, Kent P. Jensen, Everett H. Meyer
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Human regulatory T cells (Treg) suppress other immune cells. Their dysfunction contributes to the pathophysiology of autoimmune diseases, including type 1 diabetes (T1D). Infusion of Tregs is being clinically evaluated as a novel way to prevent or tr
Externí odkaz:
https://doaj.org/article/9eb5d3e2468049a48285a66700ca2b17
Autor:
Julia Koch-Heier, Annette B. Vogel, Yvonne Füll, Marina Ebensperger, Annika Schönsiegel, Raphael S. Zinser, Oliver Planz
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Regulatory T cells (Tregs) play a crucial and complex role in balancing the immune response to viral infection. Primarily, they serve to regulate the immune response by limiting the expression of proinflammatory cytokines, reducing inflammation in in
Externí odkaz:
https://doaj.org/article/2a1c5d66cd4c42598f7e351f339bb757
Autor:
Amy Rosenberg, Dawn Elaine Smilek
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/a691a80aab324171b75570edca54a277
Publikováno v:
Frontiers in Tropical Diseases, Vol 4 (2024)
Externí odkaz:
https://doaj.org/article/18bfc990cc5b4e5dbad7283a19a57f5d
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
TNFR2 agonists have been investigated as potential therapies for inflammatory diseases due to their ability to activate and expand immunosuppressive CD4+Foxp3+ Treg cells and myeloid-derived suppressor cells (MDSCs). Despite TNFR2 being predominantly
Externí odkaz:
https://doaj.org/article/a7e9dbbd20644c0aa893ae096afc439c
Autor:
Aleksi Tornio, Margherita Bigossi, Moneeza K. Siddiqui, Gwen Kennedy, Ala’a Melhem, Mehul K. Chourasia, Cyrielle Maroteau, Roberto Pola, Daniel I. Chasman, Alexander S. F. Doney, Colin N. A. Palmer
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background/Aims: Statin intolerance leads to poor adherence to statin therapy, resulting in a failure to achieve desired cholesterol reduction and adverse outcomes. The LILRB5 Asp247Gly genotype has been identified as being associated with statin int
Externí odkaz:
https://doaj.org/article/0d4d6d2d4d054897bf926eddaa49e459
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The Chromosome 22q11.2 deletion syndrome (22q11.2DS) results in an inborn error of immunity due to defective thymic organogenesis. Immunological abnormalities in 22q11.2DS patients are thymic hypoplasia, reduced output of T lymphocytes by the thymus,
Externí odkaz:
https://doaj.org/article/38e8ce56c48441cb94f1152170109710
Autor:
Joseph A. Pereira, Zachary Lanzar, Joseph T. Clark, Andrew P. Hart, Bonnie B. Douglas, Lindsey Shallberg, Keenan O’Dea, David A. Christian, Christopher A. Hunter
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
At homeostasis, a substantial proportion of Foxp3+ T regulatory cells (Tregs) have an activated phenotype associated with enhanced TCR signals and these effector Treg cells (eTregs) co-express elevated levels of PD-1 and CTLA-4. Short term in vivo bl
Externí odkaz:
https://doaj.org/article/ca90c2086bee408fa59ebce36148ce51
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/eefa5e2ba3c84bb18b19c7b466879fe9
Publikováno v:
Frontiers in Tropical Diseases, Vol 4 (2023)
IntroductionTrypanosoma evansi parasite infections cause a chronic animal wasting disease called Surra, and cases of atypical Human Trypanosomosis (aHT). In experimental models, T. evansi infections are hallmarked by the early onset of excessive infl
Externí odkaz:
https://doaj.org/article/938d6b1197554e669b5a11ade3b71b52