Zobrazeno 1 - 10
of 222
pro vyhledávání: '"Treatment benefit"'
Publikováno v:
BMC Medical Research Methodology, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Precision medicine has led to the development of targeted treatment strategies tailored to individual patients based on their characteristics and disease manifestations. Although precision medicine often focuses on a single health
Externí odkaz:
https://doaj.org/article/88f22a55f05d4c01bfdc09f53a506cf4
Autor:
R. Saúde-Conde, T. Vandamme, M. De Backer, P. Martinive, A. Covas, A. Deleporte, A. Dermine, F. Forget, K. Geboes, Q. Gilliaux, Y. Gokburun, E. Gonne, I. Joye, S. Lecomte, G. Liberale, W. Lybaert, L. Moretti, L. Mortier, S. Mupingu Mwanawa, F. Puleo, E.D. Saad, I. Sinapi, L. Annemans, M. Buyse, F. Sclafani
Publikováno v:
ESMO Gastrointestinal Oncology, Vol 4, Iss , Pp 100067- (2024)
Although total neoadjuvant therapy (TNT) is a new standard of care for locally advanced rectal cancer (LARC), there are no data to confirm the safety and efficacy of this approach in older patients. SHAPERS is a multicentre, open-label, randomised pr
Externí odkaz:
https://doaj.org/article/fba73f9b97c443b8bbc3ea74a8d54b96
Publikováno v:
Diagnostic and Prognostic Research, Vol 7, Iss 1, Pp 1-12 (2023)
Abstract Prediction algorithms that quantify the expected benefit of a given treatment conditional on patient characteristics can critically inform medical decisions. Quantifying the performance of treatment benefit prediction algorithms is an active
Externí odkaz:
https://doaj.org/article/c9e6923fff8b4780aca50b75ff2bbfd1
Akademický článek
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Publikováno v:
Mathematics, Vol 11, Iss 21, p 4459 (2023)
The average treatment effect is an important concept in causal inference. However, it fails to capture variation in response to treatment due to heterogeneity at many levels among patients in the target population. To study the heterogeneity in the t
Externí odkaz:
https://doaj.org/article/e05fc978ef7442da83cbea82388e9609
Autor:
Pinky Agarwal, Richard Barbano, Henry Moore, Marc Schwartz, Aleksej Zuzek, Marjan Sadeghi, Atul Patel
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
IntroductionThe Cervical Dystonia Patient Registry for Observation of OnabotulinumtoxinA Efficacy (CD PROBE) study (ClinicalTrials.gov identifier: NCT00836017), a multicenter, prospective, observational registry, was designed to identify real-world p
Externí odkaz:
https://doaj.org/article/5088c1f4bcb548caab87769b1538ab8b
Autor:
Fatima Cardoso, Nils Wilking, Renato Bernardini, Laura Biganzoli, Jaime Espin, Kaisa Miikkulainen, Susanne Schuurman, Danielle Spence, Sabine Spitz, Sonia Ujupan, Nicole Zernik, Jenn Gordon
Publikováno v:
Breast, Vol 52, Iss , Pp 78-87 (2020)
There is a growing understanding as science evolves that different cancer types require different approaches to treatment evaluation, especially in the metastatic stages. The introduction of new metastatic breast cancer (MBC) treatments may be hinder
Externí odkaz:
https://doaj.org/article/cfb1deae23f748f68d606e0f94891dd9
Autor:
William N. Anderson, Johan Verbeeck
Publikováno v:
Mathematics, Vol 11, Iss 6, p 1502 (2023)
To analyze multivariate outcomes in clinical trials, several authors have suggested generalizations of the univariate Mann–Whitney test. As the Mann–Whitney statistic compares the subjects’ outcome pairwise, the multivariate generalizations are
Externí odkaz:
https://doaj.org/article/c4b85e07f000481fa8a32b639bc4c18f
Akademický článek
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Autor:
Muntean Petru-Emil
Publikováno v:
Folia Medica, Vol 61, Iss 2, Pp 312-316 (2019)
Background: Sarcoidosis and tuberculosis are chronic diseases that rarely occur concomitantly. We present the case of a 39-year-old woman with microbiological confirmation of pulmonary tuberculosis and concomitant sarcoidosis. Four weeks after cortic
Externí odkaz:
https://doaj.org/article/77fc45b313824e4f830e8829b0b20b4a