Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Travis W, Bainbridge"'
Autor:
Iraj Hosseini, Brett Fleisher, Jennifer Getz, Jérémie Decalf, Mandy Kwong, Meric Ovacik, Travis W. Bainbridge, Christine Moussion, Gautham K. Rao, Kapil Gadkar, Amrita V. Kamath, Saroja Ramanujan
Publikováno v:
Pharmaceutics, Vol 16, Iss 5, p 660 (2024)
FLT3L-Fc is a half-life extended, effectorless Fc-fusion of the native human FLT3-ligand. In cynomolgus monkeys, treatment with FLT3L-Fc leads to a complex pharmacokinetic/pharmacodynamic (PK/PD) relationship, with observed nonlinear PK and expansion
Externí odkaz:
https://doaj.org/article/2aeee9c733c94287888bd277150996d7
Autor:
Christine Moussion, Dongping He, Anaïs Duval, Sarah Exbrayat, Meredith McLerie, Matthew Betzenhauser, Jérémie Decalf, Travis W Bainbridge, Christopher Kemball
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/d9437257a243483289d2f44874145c98
Autor:
William J. Meilandt, Janice A. Maloney, Jose Imperio, Guita Lalehzadeh, Tim Earr, Susan Crowell, Travis W. Bainbridge, Yanmei Lu, James A. Ernst, Reina N. Fuji, Jasvinder K. Atwal
Publikováno v:
Alzheimer’s Research & Therapy, Vol 11, Iss 1, Pp 1-14 (2019)
Abstract Background Accumulation of amyloid β (Aβ) in the brain is proposed as a cause of Alzheimer’s disease (AD), with Aβ oligomers hypothesized to be the primary mediators of neurotoxicity. Crenezumab is a humanized immunoglobulin G4 monoclon
Externí odkaz:
https://doaj.org/article/bd282779d343414aa689f312c255a80f
Autor:
Shannon J. Turley, Richard Bourgon, Christiaan Klijn, Melissa R. Junttila, Yuxin Liang, Zora Modrusan, Yasin Senbabaoglu, Alessandra Castiglioni, Travis W. Bainbridge, Oded Foreman, Beatrice Breart, Sarah Gierke, Jeffrey Hung, Hartmut Koeppen, Shilpa Keerthivasan, Sören Müller, Claudia X. Dominguez
Supplementary Figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17036d99dfac5b425f100bf442bc4078
https://doi.org/10.1158/2159-8290.22535605
https://doi.org/10.1158/2159-8290.22535605
Autor:
Shannon J. Turley, Richard Bourgon, Christiaan Klijn, Melissa R. Junttila, Yuxin Liang, Zora Modrusan, Yasin Senbabaoglu, Alessandra Castiglioni, Travis W. Bainbridge, Oded Foreman, Beatrice Breart, Sarah Gierke, Jeffrey Hung, Hartmut Koeppen, Shilpa Keerthivasan, Sören Müller, Claudia X. Dominguez
With only a fraction of patients responding to cancer immunotherapy, a better understanding of the entire tumor microenvironment is needed. Using single-cell transcriptomics, we chart the fibroblastic landscape during pancreatic ductal adenocarcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21760ad50b8a606ffa25c5c4c72872ba
https://doi.org/10.1158/2159-8290.c.6547891.v1
https://doi.org/10.1158/2159-8290.c.6547891.v1
Autor:
Ganesh Kolumam, Mark Z. Chen, Raymond Tong, Jose Zavala-Solorio, Lance Kates, Nicholas van Bruggen, Jed Ross, Shelby K. Wyatt, Vineela D. Gandham, Richard A.D. Carano, Diana Ronai Dunshee, Ai-Luen Wu, Benjamin Haley, Keith Anderson, Søren Warming, Xin Y. Rairdan, Nicholas Lewin-Koh, Yingnan Zhang, Johnny Gutierrez, Amos Baruch, Thomas R. Gelzleichter, Dale Stevens, Sharmila Rajan, Travis W. Bainbridge, Jean-Michel Vernes, Y. Gloria Meng, James Ziai, Robert H. Soriano, Matthew J. Brauer, Yongmei Chen, Scott Stawicki, Hok Seon Kim, Laëtitia Comps-Agrar, Elizabeth Luis, Christoph Spiess, Yan Wu, James A. Ernst, Owen P. McGuinness, Andrew S. Peterson, Junichiro Sonoda
Publikováno v:
EBioMedicine, Vol 2, Iss 7, Pp 730-743 (2015)
Dissipating excess calories as heat through therapeutic stimulation of brown adipose tissues (BAT) has been proposed as a potential treatment for obesity-linked disorders. Here, we describe the generation of a humanized effector-less bispecific antib
Externí odkaz:
https://doaj.org/article/acbf9281cbc1473db78d9eaceadaf5d7
Autor:
Melissa R. Junttila, Oded Foreman, Sören Müller, Béatrice Breart, Yuxin Liang, Yasin Senbabaoglu, Christiaan Klijn, Richard Bourgon, Claudia X. Dominguez, Jeffrey Hung, Shilpa Keerthivasan, Travis W. Bainbridge, Zora Modrusan, Hartmut Koeppen, Shannon J. Turley, Alessandra Castiglioni, Sarah Gierke
Publikováno v:
Cancer Discovery. 10:232-253
With only a fraction of patients responding to cancer immunotherapy, a better understanding of the entire tumor microenvironment is needed. Using single-cell transcriptomics, we chart the fibroblastic landscape during pancreatic ductal adenocarcinoma
Autor:
James A. Ernst, Tim Earr, Guita Lalehzadeh, Travis W. Bainbridge, Susan Crowell, William J. Meilandt, Jose Imperio, Reina N. Fuji, Yanmei Lu, Janice A. Maloney, Jasvinder K. Atwal
Publikováno v:
Alzheimer’s Research & Therapy, Vol 11, Iss 1, Pp 1-14 (2019)
Alzheimer's Research & Therapy
Alzheimer's Research & Therapy
Background Accumulation of amyloid β (Aβ) in the brain is proposed as a cause of Alzheimer’s disease (AD), with Aβ oligomers hypothesized to be the primary mediators of neurotoxicity. Crenezumab is a humanized immunoglobulin G4 monoclonal antibo
Autor:
David L. Lin, Varun N. Kapoor, Naruhisa Ota, Joseph Chavarria-Smith, Christian Cox, Menno van Lookeren Campagne, Travis W. Bainbridge, Noelyn M. Kljavin, Keith R. Anderson, Joseph R. Arron, Frederic J. de Sauvage, Shannon J. Turley, Yun Li, Søren Warming, Elaine E. Storm, Lifen Wang, Merone Roose-Girma
Publikováno v:
Science Immunology. 6
Repair of the intestinal epithelium is tightly regulated to maintain homeostasis. The response after epithelial damage needs to be local and proportional to the insult. How different types of damage are coupled to repair remains incompletely understo
Autor:
Travis W Bainbridge, Venita I DeAlmeida, Anita Izrael-Tomasevic, Cécile Chalouni, Borlan Pan, Joshua Goldsmith, Alia P Schoen, Gabriel A Quiñones, Ryan Kelly, Jennie R Lill, Wendy Sandoval, Mike Costa, Paul Polakis, David Arnott, Bonnee Rubinfeld, James A Ernst
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e102695 (2014)
Receptor tyrosine kinase-like orphan receptors (ROR) 1 and 2 are atypical members of the receptor tyrosine kinase (RTK) family and have been associated with several human diseases. The vertebrate RORs contain an ATP binding domain that deviates from
Externí odkaz:
https://doaj.org/article/080290e22e094a90849ffe90a71ec97c