Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Travis S. Young"'
Autor:
Leopold Garnar-Wortzel, Timothy R. Bishop, Seiya Kitamura, Natalia Milosevich, Joshua N. Asiaban, Xiaoyu Zhang, Qinheng Zheng, Emily Chen, Anissa R. Ramos, Christopher J. Ackerman, Eric N. Hampton, Arnab K. Chatterjee, Travis S. Young, Mitchell V. Hull, K. Barry Sharpless, Benjamin F. Cravatt, Dennis W. Wolan, Michael A. Erb
Publikováno v:
ACS Central Science, Vol 7, Iss 5, Pp 815-830 (2021)
Externí odkaz:
https://doaj.org/article/097fa2b7ad3f4a1fa4c7766ad3a5dcd3
Autor:
Ivo Rimann, Hua Huang, Parker Mace, Rosana Gonzalez-Quintial, Eduardo Laborda, Sophie Viaud, Hannah Mora, Argyrios N Theofilopoulos, Travis S Young, Dwight H Kono
Publikováno v:
Lupus 21st Century 2022 Abstract.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3cc5b1f4d5b22522a1f0b5cdf60444a8
https://doi.org/10.1136/lupus-2022-lupus21century.87
https://doi.org/10.1136/lupus-2022-lupus21century.87
Autor:
Christopher A Pennell, Heather Campbell, Meghan D Storlie, Sara Bolivar-Wagers, Mark J Osborn, Yosef Refaeli, Michael Jensen, Sophie Viaud, Travis S Young, Bruce R Blazar
Publikováno v:
Journal for immunotherapy of cancer. 10(12)
Current Food and Drug Administration (FDA)-approved CD19-specific chimeric antigen receptor (CAR) T-cell therapies for B-cell malignancies are constitutively active and while efficacious, can cause morbidity and mortality. Their toxicities might be r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::136bd0febf16faa9a4bc585ab037920d
https://pubmed.ncbi.nlm.nih.gov/36521930
https://pubmed.ncbi.nlm.nih.gov/36521930
Autor:
Flavian Thelen, Joseph M McGraw, Deborah A. Witherden, Wendy L. Havran, Nelson E Bruno, Eric N. Hampton, Travis S. Young
Publikováno v:
Journal of Experimental Medicine. 218
T cells are critical mediators of antitumor immunity and a major target for cancer immunotherapy. Antibody blockade of inhibitory receptors such as PD-1 can partially restore the activity of tumor-infiltrating lymphocytes (TILs). However, the activat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79bdc9d8f1cff59b3f3eaec8982e0ce2
https://doi.org/10.1084/jem.20202644
https://doi.org/10.1084/jem.20202644
Autor:
Christina Jamieson, Sung Chang Lee, Jennifer Ma, Sean B. Joseph, Minsoo Kim, Anna A. Kulidjian, Peter G. Schultz, Ashley K. Woods, Wenxue Ma, Mike Petrassi, Michelle Muldong, Travis S. Young, Hwayoung Yun, Christopher J. Kane, Eric N. Hampton, Chan Hyuk Kim, Jing Li, Vanessa Núñez, Eduardo Laborda, Klyushnichenko Vadim, Sei-hyun Choi, John Wisler, Christina C. N. Wu
Publikováno v:
Science Advances
Science advances, vol 7, iss 33
Science advances, vol 7, iss 33
CCW702 is a bispecific antibody that combines the specificity of an imaging ligand with the potency of a T cell immunotherapy.
Despite the development of next-generation antiandrogens, metastatic castration-resistant prostate cancer (mCRPC) rema
Despite the development of next-generation antiandrogens, metastatic castration-resistant prostate cancer (mCRPC) rema
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f980a0dc297d3c689185170e7863bb3
https://pubmed.ncbi.nlm.nih.gov/34380625
https://pubmed.ncbi.nlm.nih.gov/34380625
Autor:
Benjamin F. Cravatt, Qinheng Zheng, Leopold Garnar-Wortzel, Eric N. Hampton, Seiya Kitamura, Anissa R. Ramos, Michael A. Erb, Joshua N. Asiaban, Natalia Milosevich, K. Barry Sharpless, Xiaoyu Zhang, Emily Chen, Travis S. Young, Timothy R. Bishop, Arnab K. Chatterjee, Christopher J. Ackerman, Dennis W. Wolan, Mitchell V. Hull
Transcriptional co-regulators, which mediate chromatin-dependent transcriptional signaling, represent tractable targets to modulate tumorigenic gene expression programs with small molecules. Genetic loss-of-function studies have recently implicated t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5d4cf4198bd8dc8c44f5702413eca61
https://doi.org/10.1101/2020.12.01.406694
https://doi.org/10.1101/2020.12.01.406694
Autor:
Justin Wang, Michael A. Erb, Timothy R. Bishop, Natalia Milosevich, Yuxiang Zhang, Travis S. Young, Christopher J Ackerman, Eric N Hampton, Joshua N Asiaban, Emily Chen, Mitchell V. Hull, Benjamin F. Cravatt
Publikováno v:
ACS Chem Biol
ENL is a transcriptional co-activator that recruits elongation machinery to active cis-regulatory elements upon binding of its YEATS domain – a chromatin reader module – to acylated lysine side chains. Discovery chemistry for the ENL YEATS domain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48bf4d3fcd795b9e59e3bcca5e0dc75e
https://pubmed.ncbi.nlm.nih.gov/32176478
https://pubmed.ncbi.nlm.nih.gov/32176478
Autor:
H. Michael Petrassi, Emily N. Chin, Mildred Kissai, Arnab K. Chatterjee, Dennis W. Wolan, Alan Chu, John R. Teijaro, Ashley K. Woods, Ana M. Gamo, Daniel C. Lazar, Nhan T. Nguyen, Peter G. Schultz, Vincent F. Vartabedian, Ying Jia, Kristen Johnson, Travis S. Young, Manoj Kumar, Sean B. Joseph, Eric Hampton, Francisco Martínez-Peña, Chenguang Yu, William Vernier, Luke L. Lairson, Brent Benish, Sabrina H. Ali, Laura E. Pereira, Philipp N. Sander
Publikováno v:
Science (New York, N.Y.). 369(6506)
Stimulator of interferon genes (STING) links innate immunity to biological processes ranging from antitumor immunity to microbiome homeostasis. Mechanistic understanding of the anticancer potential for STING receptor activation is currently limited b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdc9cc2fcfddf93c642325863f5890bf
https://pubmed.ncbi.nlm.nih.gov/32901152
https://pubmed.ncbi.nlm.nih.gov/32901152
Autor:
Travis S. Young, Eduardo Laborda
Publikováno v:
Cell and Gene Therapy Insights. 4:275-285
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be04ea38e9f2c95432ee484b2d234929
https://doi.org/10.18609/cgti.2018.028
https://doi.org/10.18609/cgti.2018.028
Autor:
Vadim Baidin, David Tomasek, Travis S. Young, Case W. McNamara, Eileen Moison, Nitya S. Ramadoss, Peter G. Schultz, Daniel Kahne, Ge Zhang, Timothy C. Meredith, Arnab Chatterjee, Karanbir S. Pahil
Publikováno v:
Proceedings of the National Academy of Sciences. 115:6834-6839
New drugs are needed to treat gram-negative bacterial infections. These bacteria are protected by an outer membrane which prevents many antibiotics from reaching their cellular targets. The outer leaflet of the outer membrane contains LPS, which is r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20a6d9e45820c7279ed7b812391c4bec
https://doi.org/10.1073/pnas.1804670115
https://doi.org/10.1073/pnas.1804670115