Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Travis R. Taylor"'
Publikováno v:
Xenotransplantation. 25(6)
Autor:
Adaeze O, Izuogu, Travis R, Taylor
Publikováno v:
Bio Protoc
Cellular infection with tick-borne flaviviruses (TBFVs) results in activation of the interferon (IFN) signaling pathway and subsequent upregulation of numerous genes termed IFN stimulated genes (ISGs) ( Schoggins et al., 2011 ). Many ISGs function to
Autor:
Travis R. Taylor, Christopher Burlak
Publikováno v:
Xenotransplantation. 22:490-492
Autor:
Travis R. Taylor, Christopher Burlak
Publikováno v:
Xenotransplantation. 25:e12389
Autor:
Thomas J, Urban, Chen, Yang, Leah L, Lagpacan, Chaline, Brown, Richard A, Castro, Travis R, Taylor, Conrad C, Huang, Douglas, Stryke, Susan J, Johns, Michiko, Kawamoto, Elaine J, Carlson, Thomas E, Ferrin, Esteban G, Burchard, Kathleen M, Giacomini
Publikováno v:
Pharmacogenetics and Genomics. 17:773-782
OCTN1 is a multispecific transporter of organic cations and zwitterions, including several clinically important drugs as well as the antioxidant ergothioneine. OCTN1 is highly expressed in the kidney, where it is thought to aid in active secretion of
Interaction of Methotrexate with Organic-Anion Transporting Polypeptide 1A2 and Its Genetic Variants
Autor:
Ilaria Badagnani, Esteban G. Burchard, Travis R. Taylor, Michiko Kawamoto, Richard A. Castro, Elaine J. Carlson, Douglas Stryke, Conrad C. Huang, Kathleen M. Giacomini, Claire M. Brett, Susan J. Johns, Thomas E. Ferrin
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 318:521-529
Methotrexate (MTX) is used in patients with malignant and autoimmune diseases. This drug is primarily excreted unchanged in the urine, and its net excretion occurs via active secretory and reabsorptive processes. We characterized the interaction of M
Autor:
Melanie De La Cruz, Esteban G. Burchard, Leah L. Lagpacan, Kathleen M. Giacomini, Elaine J. Carlson, Douglas Stryke, Travis R. Taylor, Claire M. Brett, Conrad C. Huang, Thomas J. Urban, Thomas E. Ferrin, Lara M. Mangravite, Susan J. Johns, Michiko Kawamoto, Andrew R. Erdman, Richard A. Castro, Wendy Chan
Publikováno v:
American Journal of Physiology-Renal Physiology. 290:F905-F912
The human organic anion transporter, OAT3 ( SLC22A8), plays a critical role in renal drug elimination, by mediating the entry of a wide variety of organic anions, including a number of commonly used pharmaceuticals, into the renal proximal tubular ce
Autor:
Conrad C. Huang, Doug Stryke, Susan J. Johns, Jennifer H. Gray, Ryan P. Owen, Kathleen M. Giacomini, Travis R. Taylor, Elaine J. Carlson, Michiko Kawamoto, Thomas E. Ferrin
Publikováno v:
Pharmacogenetics and Genomics. 15:83-90
The concentrative nucleoside transporter CNT2 (SPNT1; SLC28A2) plays a role in the absorption and disposition of naturally occurring nucleosides, as well as nucleoside analog drugs. The aim of the present study was to characterize genetic variation i
Autor:
Kathleen M. Giacomini, Maya K. Leabman, Melanie De La Cruz, Thomas E. Ferrin, Joseph DeYoung, Elaine J. Carlson, Travis R. Taylor, Susan J. Johns, Deanna L. Kroetz, Ira Herskowitz, Conrad C. Huang, Andrew G. Clark, Neil Risch, Thomas J. Urban, Michiko Kawamoto, Doug Stryke
Publikováno v:
Proceedings of the National Academy of Sciences. 100:5896-5901
Membrane transporters maintain cellular and organismal homeostasis by importing nutrients and exporting toxic compounds. Transporters also play a crucial role in drug response, serving as drug targets and setting drug levels. As part of a pharmacogen
Publikováno v:
The Journal of Chemical Physics. 117:8644-8656
The low-lying electronic states of AlP, GaP, InP, and GaAs have been probed using anion photoelectron spectroscopy and zero electronic kinetic energy spectroscopy. We observe transitions from the anion 2Σ+ and low-lying 2Π states to the triplet (3