Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Travis M Blimkie"'
Autor:
Lauren V Wilkinson, Morgan A Alford, Shannon R Coleman, Bing C Wu, Amy H Y Lee, Travis M Blimkie, Manjeet Bains, Reza Falsafi, Daniel Pletzer, Robert E W Hancock
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0250977 (2021)
Pseudomonas aeruginosa is a ubiquitous opportunistic pathogen that causes considerable human morbidity and mortality, particularly in nosocomial infections and individuals with cystic fibrosis. P. aeruginosa can adapt to surface growth by undergoing
Externí odkaz:
https://doaj.org/article/ae510231c40c4d9ebd4abbcf89af58d8
Autor:
Daniel Pletzer, Evelyn Sun, Caleb Ritchie, Lauren Wilkinson, Leo T Liu, Michael J Trimble, Heidi Wolfmeier, Travis M Blimkie, Robert E W Hancock
Publikováno v:
PLoS Pathogens, Vol 16, Iss 3, p e1008444 (2020)
Cystic fibrosis (CF) is a genetic disease that affects mucin-producing body organs such as the lungs. Characteristic of CF is the production of thick, viscous mucus, containing the glycoprotein mucin, that can lead to progressive airway obstruction.
Externí odkaz:
https://doaj.org/article/d88ada66a6684776984907b7e6f26fb8
Autor:
Andy Yi An, Arjun Baghela, Peter G. Y. Zhang, Travis M. Blimkie, Jeff Gauthier, Daniel Elias Kaufmann, Erica Acton, Amy H. Y. Lee, Roger C. Levesque, Robert E. W. Hancock
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionPersistent symptoms after COVID-19 infection (“long COVID”) negatively affects almost half of COVID-19 survivors. Despite its prevalence, its pathophysiology is poorly understood, with multiple host systems likely affected. Here, we f
Externí odkaz:
https://doaj.org/article/847c7a1bfa6448129c35b711a7569eb0
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundSepsis is a dysfunctional host response to infection. The syndrome leads to millions of deaths annually (19.7% of all deaths in 2017) and is the cause of most deaths from severe Covid infections. High throughput sequencing or ‘omics’ ex
Externí odkaz:
https://doaj.org/article/f08ced65fdcb4eb79b0d066964ca14f0
Autor:
Corrie R. Belanger, Melanie Dostert, Travis M. Blimkie, Amy Huei-Yi Lee, Bhavjinder Kaur Dhillon, Bing Catherine Wu, Noushin Akhoundsadegh, Negin Rahanjam, Javier Castillo-Arnemann, Reza Falsafi, Daniel Pletzer, Cara H. Haney, Robert E. W. Hancock
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Pseudomonas aeruginosa, like other pathogens, adapts to the limiting nutritional environment of the host by altering patterns of gene expression and utilizing alternative pathways required for survival. Understanding the genes essential for survival
Externí odkaz:
https://doaj.org/article/f18b987a41e34bd9aa29b6893415d7a8
Autor:
Bing (Catherine) Wu, Travis M. Blimkie, Evan F. Haney, Reza Falsafi, Noushin Akhoundsadegh, Robert E. W. Hancock
Publikováno v:
Cells, Vol 11, Iss 21, p 3459 (2022)
Bacterial biofilm infections associated with wounded skin are prevalent, recalcitrant, and in urgent need of treatments. Additionally, host responses in the skin to biofilm infections are not well understood. Here we employed a human organoid skin mo
Externí odkaz:
https://doaj.org/article/5e3c3ff83c4b40b5a3c4fb67cfc1dd6e
Autor:
Rym Ben-Othman, Bing Cai, Aaron C. Liu, Natallia Varankovich, Daniel He, Travis M. Blimkie, Amy H. Lee, Erin E. Gill, Mark Novotny, Brian Aevermann, Sibyl Drissler, Casey P. Shannon, Sarah McCann, Kim Marty, Gordean Bjornson, Rachel D. Edgar, David Tse Shen Lin, Nicole Gladish, Julia Maclsaac, Nelly Amenyogbe, Queenie Chan, Alba Llibre, Joyce Collin, Elise Landais, Khoa Le, Samantha M. Reiss, Wayne C. Koff, Colin Havenar-Daughton, Manraj Heran, Bippan Sangha, David Walt, Mel Krajden, Shane Crotty, Devin Sok, Bryan Briney, Dennis R. Burton, Darragh Duffy, Leonard J. Foster, William W. Mohn, Michael S. Kobor, Scott J. Tebbutt, Ryan R. Brinkman, Richard H. Scheuermann, Robert E. W. Hancock, Tobias R. Kollmann, Manish Sadarangani
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Conventional vaccine design has been based on trial-and-error approaches, which have been generally successful. However, there have been some major failures in vaccine development and we still do not have highly effective licensed vaccines for tuberc
Externí odkaz:
https://doaj.org/article/161a4130886644838de4892cc5710d1d
Autor:
Melanie Dostert, Corrie R. Belanger, Lucas Pedraz, Morgan A. Alford, Travis M. Blimkie, Reza F. Falsafi, Manjeet Bains, Bhavjinder Kaur Dhillon, Cara H. Haney, Amy H. Lee, Robert E. W. Hancock
Publikováno v:
Frontiers in Microbiology. 13
Biofilms are the most common cause of bacterial infections in humans and notoriously hard to treat due to their ability to withstand antibiotics and host immune defenses. To overcome the current lack of effective antibiofilm therapies and guide futur
Autor:
Patrick Graff, Jenny Wilzopolski, Anne Voss, Travis M. Blimkie, January Weiner, Olivia Kershaw, Preety Panwar, Tillie Hackett, Dieter Brömme, Lucie Loyal, Andreas Thiel, Dieter Beule, Robert E.W. Hancock, Achim D. Gruber, Wolfgang Bäumer, Sarah Hedtrich
The development of atopic dermatitis (AD) in infancy, and subsequent allergic rhinitis, food allergies, and asthma in later childhood, is known as the atopic march. The mechanism is largely unknown, yet the course of disease indicates the contributio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::792f17a055b2f3ca2fad21b828610332
https://doi.org/10.1101/2022.01.17.22269397
https://doi.org/10.1101/2022.01.17.22269397
Autor:
Brian D. Aevermann, Casey P. Shannon, Mark Novotny, Rym Ben-Othman, Bing Cai, Yun Zhang, Jamie C. Ye, Michael S. Kobor, Nicole Gladish, Amy Huei-Yi Lee, Travis M. Blimkie, Robert E. Hancock, Alba Llibre, Darragh Duffy, Wayne C. Koff, Manish Sadarangani, Scott J. Tebbutt, Tobias R. Kollmann, Richard H. Scheuermann
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Frontiers, 2021, 12, pp.690470. ⟨10.3389/fimmu.2021.690470⟩
Frontiers in Immunology, 2021, 12, pp.690470. ⟨10.3389/fimmu.2021.690470⟩
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology, Frontiers, 2021, 12, pp.690470. ⟨10.3389/fimmu.2021.690470⟩
Frontiers in Immunology, 2021, 12, pp.690470. ⟨10.3389/fimmu.2021.690470⟩
Frontiers in Immunology, Vol 12 (2021)
International audience; Vaccination to prevent infectious disease is one of the most successful public health interventions ever developed. And yet, variability in individual vaccine effectiveness suggests that a better mechanistic understanding of v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c750a2878091c4b59d184e48a27bfc79
https://hal-pasteur.archives-ouvertes.fr/pasteur-03517632/file/fimmu-12-690470.pdf
https://hal-pasteur.archives-ouvertes.fr/pasteur-03517632/file/fimmu-12-690470.pdf