Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Travis Leedahl"'
Autor:
Sanku Mallik, Travis Leedahl, Raushan K. Singh, Abigail McGillivray, Naveena Lall, Manas K. Haldar, D. K. Srivastava, Tanmay Mandal, Gregory R. Cook
Publikováno v:
Biochemistry. 52:8139-8149
Of the different hydroxamate-based histone deacetylase (HDAC) inhibitors, suberoylanilide hydroxamic acid (SAHA) has been approved by the Food and Drug Administration for the treatment of T-cell ly...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3ab4e307a93d8f3addb087e727c132e
https://doi.org/10.1021/bi400740x
https://doi.org/10.1021/bi400740x
Publikováno v:
Chemico-Biological Interactions. 191:147-152
Aldehyde dehydrogenase 2 (ALDH2) catalyzes oxidation of toxic aldehydes to carboxylic acids. Physiologic levels of Mg(2+) ions influence ALDH2 activity in part by increasing NADH binding affinity. Traditional fluorescence measurements monitor the blu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fda92e57274f0c621483c3babeab91d
https://doi.org/10.1016/j.cbi.2011.01.023
https://doi.org/10.1016/j.cbi.2011.01.023
Autor:
Travis Leedahl, Raushan K. Singh, Dustin Mueller, Gregory R. Cook, Junru Yu, Narayanganesh Balasubranian, D. K. Srivastava, Joseph N. Omlid
Publikováno v:
The FASEB Journal. 28
Histone deacetylase 4 (HDAC4) is a high priority drug target for the treatment of various human diseases including Huntington’s disease and various cancers. Pan-HDAC inhibitors, such as Suberoylani...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04827a8f3f6b656b4301d0c40e9b41a3
https://doi.org/10.1096/fasebj.28.1_supplement.768.19
https://doi.org/10.1096/fasebj.28.1_supplement.768.19
Autor:
Tanmay Mandal, D. K. Srivastava, Nitesh Sule, Tajae Viaene, Gregory R. Cook, Raushan K. Singh, Narayanaganesh Balsubramanian, Travis Leedahl
We report, for the first time, that certain N -acetylthiourea derivatives serve as highly potent and isozyme selective activators for the recombinant form of human histone deacetylase-8 in the assay system containing Fluor-de-Lys as a fluorescent sub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea1ce36dcb889902fa9c528b323c9227
https://europepmc.org/articles/PMC3171571/
https://europepmc.org/articles/PMC3171571/
