Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Travis J Morgenstern"'
Publikováno v:
eLife, Vol 8 (2019)
Inhibiting high-voltage-activated calcium channels (HVACCs; CaV1/CaV2) is therapeutic for myriad cardiovascular and neurological diseases. For particular applications, genetically-encoded HVACC blockers may enable channel inhibition with greater tiss
Externí odkaz:
https://doaj.org/article/e56ce6dd3efa4e69a83ce9aa4dcbc733
Autor:
Zachary J Farino, Travis J Morgenstern, Julie Vallaghe, Nathalie Gregor, Prashant Donthamsetti, Paul E Harris, Nicolas Pierre, Robin Freyberg, Fabienne Charrier-Savournin, Jonathan A Javitch, Zachary Freyberg
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0148684 (2016)
Direct measurement of insulin is critical for basic and clinical studies of insulin secretion. However, current methods are expensive and time-consuming. We developed an insulin assay based on homogenous time-resolved fluorescence that is significant
Externí odkaz:
https://doaj.org/article/d5d1b9e483904f1da5f84e0c75cfd217
Autor:
Elena Poggio, Francesca Vallese, Andreas J. W. Hartel, Travis J. Morgenstern, Scott A. Kanner, Oliver Rauh, Flavia Giamogante, Lucia Barazzuol, Kenneth L. Shepard, Henry M. Colecraft, Oliver Biggs Clarke, Marisa Brini, Tito Calì
Publikováno v:
Cell Death and Disease, Vol 14, Iss 4, Pp 1-13 (2023)
Abstract Coronavirus disease (COVID-19) is a contagious respiratory disease caused by the SARS-CoV-2 virus. The clinical phenotypes are variable, ranging from spontaneous recovery to serious illness and death. On March 2020, a global COVID-19 pandemi
Externí odkaz:
https://doaj.org/article/6f24462f2be0478e821b38710e7c6258
Autor:
Travis J. Morgenstern, Neha Nirwan, Erick O. Hernández-Ochoa, Hugo Bibollet, Papiya Choudhury, Yianni D. Laloudakis, Manu Ben Johny, Roger A. Bannister, Martin F. Schneider, Daniel L. Minor, Henry M. Colecraft
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
Auxiliary subunit molecular diversity is an unexploited target for developing ion channel inhibitors. Here, the authors develop a general approach to inhibit ion channels based on the resident auxiliary subunit isoform to elucidate unique functions o
Externí odkaz:
https://doaj.org/article/6afcd6383eb345e8b49429eb383e8ae1
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(20)
Neuropathic pain caused by lesions to somatosensory neurons due to injury or disease is a widespread public health problem that is inadequately managed by small-molecule therapeutics due to incomplete pain relief and devastating side effects. Genetic
Publikováno v:
Methods in enzymology. 654
Plasma membrane-localized ion channels are essential for diverse physiological processes such as neurotransmission, muscle contraction, and osmotic homeostasis. The surface density of such ion channels is a major determinant of their function, and tu
Publikováno v:
Methods in Enzymology ISBN: 9780128239247
Plasma membrane-localized ion channels are essential for diverse physiological processes such as neurotransmission, muscle contraction, and osmotic homeostasis. The surface density of such ion channels is a major determinant of their function, and tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::575f9be5ef23c80c488b1172640cace7
https://doi.org/10.1016/bs.mie.2021.03.007
https://doi.org/10.1016/bs.mie.2021.03.007
Autor:
Travis J. Morgenstern, Arden Darko-Boateng, Papiya Choudhury, Sri Karthika Shanmugam, Xinle Zou, Henry M. Colecraft
Publikováno v:
Biophysical Journal. 121:385a
Autor:
Stephen D. Carter, Wen Li, Sandra A. Murray, Deborah Fass, Jenny I. Aguilar, José María Carazo, Meir Aridor, Michael J. Calderon, Sruti Shiva, Leanna Eisenman, Zachary J. Farino, Elana S. Levy, Stephanie E. Siegmund, William J. Rice, Allen Volchuk, Jyotsna Pilli, Edward Yi, Robin Freyberg, Robert A. Grassucci, Christoph Wigge, Tamas Balla, Grant J. Jensen, Zachary Freyberg, Nili L. Greenberg, Roberto Melero, Kenneth N. Fish, Travis J Morgenstern, Cheri M. Hampton, Estela Area-Gomez, Maïté Courel, Joshua G. Pemberton, Sharon G. Wolf, Callen T. Wallace, William G. Mitchell, Joachim Frank, Emily W. George, Simon C. Watkins, Ngoc-Han Tran, Zachary P. Wills, Robert Langlois, Despoina Aslanoglou, Francesca Bartolini, Peter Walter, Jonathan A. Javitch
Publikováno v:
Science advances, vol 6, iss 14
Science Advances
Digital.CSIC. Repositorio Institucional del CSIC
instname
Science Advances
Digital.CSIC. Repositorio Institucional del CSIC
instname
The endoplasmic reticulum (ER) is a highly dynamic network of membranes. Here, we combine live-cell microscopy with in situ cryo-electron tomography to directly visualize ER dynamics in several secretory cell types including pancreatic β-cells and n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad6c12563619c7bb859ab52fcc61cc9e
https://escholarship.org/uc/item/54c9n3tb
https://escholarship.org/uc/item/54c9n3tb