Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Travis J McQuiston"'
Autor:
Ali Vural, Travis J McQuiston, Joe B Blumer, Chung Park, Il-Young Hwang, Yolanda Williams-Bey, Chong-Shan Shi, Dzwokai Zach Ma, John H Kehrl
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e81886 (2013)
In macrophages autophagy assists antigen presentation, affects cytokine release, and promotes intracellular pathogen elimination. In some cells autophagy is modulated by a signaling pathway that employs Gαi3, Activator of G-protein Signaling-3 (AGS3
Externí odkaz:
https://doaj.org/article/00a6c4505f594d4db90ac089796632c7
Autor:
Chengkang Zhang, Hyung Joo Lee, Anura Shrivastava, Ruipeng Wang, Travis J. McQuiston, Sharon S. Challberg, Brian A. Pollok, Ting Wang
Publikováno v:
Cell Reports, Vol 25, Iss 3, Pp 598-610.e5 (2018)
Summary: Despite substantial self-renewal capability in vivo, epithelial stem and progenitor cells located in various tissues expand for a few passages in vitro in feeder-free condition before they succumb to growth arrest. Here, we describe the EpiX
Externí odkaz:
https://doaj.org/article/7e6c0236232d4c41b483b38df821a891
Autor:
Travis J. McQuiston, Zhijuan Qiu, Barbara Nuesslein-Hildesheim, Arielle M. Bryan, Cristina Lazzarini, Maurizio Del Poeta, Jeehyun Karen You, Brian S. Sheridan
Publikováno v:
J Clin Invest
FTY720 is a treatment for relapsing remitting multiple sclerosis (MS). It is an analog of sphingosine-1-phosphate (S1P) and targets S1P receptors 1, 3, 4, and 5. Recent reports indicate an association between long-term exposure to FTY720 and cases of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9460676d52b0360e174dce5c74c7884e
https://doi.org/10.1172/jci136068
https://doi.org/10.1172/jci136068
Autor:
Travis J. McQuiston, Joe B. Blumer, Gordon Y. C. Cheung, Lalitha Srinivasan, John H. Kehrl, Il Young Hwang, Ali Vural, Souhaila Al-Khodor, Peter R. Williamson, Chong-Shan Shi, Michael Otto, Iain D. C. Fraser, Volker Briken, Anthony J. Yeh
Publikováno v:
The Journal of Immunology. 196:846-856
Many intracellular pathogens cause disease by subverting macrophage innate immune defense mechanisms. Intracellular pathogens actively avoid delivery to or directly target lysosomes, the major intracellular degradative organelle. In this article, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd98207acc7691a6c506b469cba810a5
https://doi.org/10.4049/jimmunol.1501595
https://doi.org/10.4049/jimmunol.1501595
Autor:
Travis J. McQuiston, Sharon S. Challberg, Brian A. Pollok, Chengkang Zhang, Anura Shrivastava, Ting Wang, Hyung Joo Lee, Ruipeng Wang
Publikováno v:
Cell reports
Cell Reports, Vol 25, Iss 3, Pp 598-610.e5 (2018)
Cell Reports, Vol 25, Iss 3, Pp 598-610.e5 (2018)
SUMMARY Despite substantial self-renewal capability in vivo, epithelial stem and progenitor cells located in various tissues expand for a few passages in vitro in feeder-free condition before they succumb to growth arrest. Here, we describe the EpiX
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccbb7f72787386f32794a95dd5ae27e4
https://pubmed.ncbi.nlm.nih.gov/30332641
https://pubmed.ncbi.nlm.nih.gov/30332641
Autor:
Gulbu Uzel, Ali Vural, Yoon Dong Park, Travis J. McQuiston, Timothy G. Myers, Amélie Bernard, John H. Kehrl, Richard J. Maraia, Daniel J. Klionsky, Jin Qiu, Scott R. Waterman, Peter R. Williamson, Guowu Hu, Nannan Zhang, Nathan H. Blewett
Publikováno v:
Nature cell biology
Microbial Cell
Microbial Cell
Eukaryotic cells utilize macroautophagy (hereafter autophagy) to recycle cellular materials during nutrient stress. Target of rapamycin (Tor) is a central regulator of this process, acting by post-translational mechanisms, phosphorylating preformed a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71d4989ea581dc700550522eb3018018
https://doi.org/10.1038/ncb3189
https://doi.org/10.1038/ncb3189
Autor:
David Whitston, Alexandra Borodovsky, Brian A. Pollok, Travis J. McQuiston, Celina M. D'Cruz, Brian Dougherty, Michael Grondine, Deborah Lawson, Sharon S. Challberg, Ambar Ahmed, Jingwen Zhang, Daniel Stetson, Michael Zinda
Publikováno v:
Molecular Cancer
Molecular Cancer, Vol 16, Iss 1, Pp 1-7 (2017)
Molecular Cancer, Vol 16, Iss 1, Pp 1-7 (2017)
Efforts to develop effective cancer therapeutics have been hindered by a lack of clinically predictive preclinical models which recapitulate this complex disease. Patient derived xenograft (PDX) models have emerged as valuable tools for translational
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c51bf1fec20f3d8c231c1b767898d3e6
https://doi.org/10.1186/s12943-017-0745-1
https://doi.org/10.1186/s12943-017-0745-1
Autor:
Nathan H. Blewett, Peter R. Williamson, Gulbu Uzel, Daniel J. Klionsky, Jin Qiu, Guowu Hu, Nannan Zhang, Scott R. Waterman, Timothy G. Myers, John H. Kehrl, Ali Vural, Travis J. McQuiston, Amélie Bernard, Yoon-Dong Park
Publikováno v:
Microbial Cell, Vol 2, Iss 8, Pp 302-304 (2015)
Eukaryotic cells utilize macroautophagy (hereafter autophagy) to recycle cellular materials during nutrient stress. Target of rapamycin (Tor) is a central regulator of this process, acting by post-translational mechanisms, phosphorylating preformed a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e943573c35b0c8356fce00aab52221a
http://microbialcell.com/researcharticles/the-role-of-transcriptional-futile-cycles-in-autophagy-and-microbial-pathogenesis/
http://microbialcell.com/researcharticles/the-role-of-transcriptional-futile-cycles-in-autophagy-and-microbial-pathogenesis/
Publikováno v:
Infection and Immunity. 78:2342-2352
Cryptococcus neoformansis a fungal pathogen causing pulmonary infection and a life-threatening meningoencephalitis in human hosts. The fungus infects the host through inhalation, and thus, the host response in the lung environment is crucial for cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8050cef8e4c350e70b4b7540b4c22dea
https://doi.org/10.1128/iai.01140-09
https://doi.org/10.1128/iai.01140-09
Autor:
Yoon Dong Park, Timothy G. Myers, John H. Kehrl, Richard J. Maraia, Jin Qiu, Daniel J. Klionsky, Guowu Hu, Nannan Zhang, Scott R. Waterman, Nathan H. Blewett, Travis J. McQuiston, Peter R. Williamson, Ali Vural, Amélie Bernard, Gulbu Uzel
Regulation of autophagy is required to maintain cellular equilibrium and prevent disease. While extensive study of post-translational mechanisms has yielded important insights into autophagy induction, less is known about post-transcriptional mechani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fa4d9dd2f9e276c668aba9bd9208e16
https://europepmc.org/articles/PMC4835197/
https://europepmc.org/articles/PMC4835197/
