Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Travis J Jewett"'
Publikováno v:
PLoS ONE, Vol 18, Iss 6, p e0286959 (2023)
Colonization of a localized area of human skin by Borrelia burgdorferi after a bite from an infected tick is the first step in the development of Lyme disease. The initial interaction between the pathogen and the human host cells is suggested to impa
Externí odkaz:
https://doaj.org/article/97bf2f366908418bbc6d981972f20f2b
Autor:
Hunter W Kuhn, Amanda G Lasseter, Philip P Adams, Carlos Flores Avile, Brandee L Stone, Darrin R Akins, Travis J Jewett, Mollie W Jewett
Publikováno v:
PLoS Pathogens, Vol 17, Iss 8, p e1009869 (2021)
The Lyme disease spirochete Borrelia burgdorferi relies on uptake of essential nutrients from its host environments for survival and infection. Therefore, nutrient acquisition mechanisms constitute key virulence properties of the pathogen, yet these
Externí odkaz:
https://doaj.org/article/83133a61316f4c7694a6b07daadd1c8f
Publikováno v:
PLoS Pathogens, Vol 6, Iss 7, p e1000997 (2010)
The translocated actin recruiting phosphoprotein (Tarp) is conserved among all pathogenic chlamydial species. Previous reports identified single C. trachomatis Tarp actin binding and proline rich domains required for Tarp mediated actin nucleation. A
Externí odkaz:
https://doaj.org/article/04086c9925cd4df38be5790d0e030434
Publikováno v:
Frontiers in Cellular and Infection Microbiology. 12
The intracellular pathogen Chlamydia trachomatis secretes multiple early effectors into the host cell to promote invasion. A key early effector during host cell entry, Tarp (translocated actin-recruiting phosphoprotein) is comprised of multiple prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::824c788fb7054b54f7adc3cf4ebedf92
https://doi.org/10.3389/fcimb.2022.811407
https://doi.org/10.3389/fcimb.2022.811407
Autor:
Madelyn H. Miller, Lindsay G. Swaby, Vanessa S. Vailoces, Maggie LaFratta, Yuan Zhang, Xiang Zhu, Dorilyn J. Hitchcock, Travis J. Jewett, Bin Zhang, Justine T. Tigno-Aranjuez
Publikováno v:
Cell Rep
Development of therapies with the potential to change the allergic asthmatic disease course will require the discovery of targets that play a central role during the initiation of an allergic response, such as those involved in the process of allerge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::190ac51067963c4b6be0fb68f4e700d1
https://doi.org/10.1016/j.celrep.2023.112208
https://doi.org/10.1016/j.celrep.2023.112208
Publikováno v:
Frontiers in cellular and infection microbiology. 12
The intracellular pathogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::647720fc104984b41869d5c4958bbff7
https://pubmed.ncbi.nlm.nih.gov/35300377
https://pubmed.ncbi.nlm.nih.gov/35300377
Publikováno v:
Biochem Biophys Res Commun
Chlamydia trachomatis injects bacterial effector proteins into human epithelial cells to facilitate the establishment of new infections. The chlamydial type III secreted effector t ranslocated a ctin r ecruiting phospho p rotein (Tarp) has been shown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d1bb5f4f0a0e85e07b62a1518489702
https://europepmc.org/articles/PMC8206025/
https://europepmc.org/articles/PMC8206025/
Publikováno v:
mBio
mBio, Vol 12, Iss 1 (2021)
mBio, Vol 12, Iss 1 (2021)
The increasing genetic tractability of Chlamydia trachomatis is accelerating the ability to characterize the unique infection biology of this obligate intracellular parasite. These efforts are leading to a greater understanding of the molecular event
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4c8d72f181078a581de0af215500f55
https://pubmed.ncbi.nlm.nih.gov/33468693
https://pubmed.ncbi.nlm.nih.gov/33468693
Autor:
Elizabeth A. Ruelke, Maria Bodero, Susmita Ghosh, Kenneth A. Fields, Travis J. Jewett, Joshua C. Ferrell
Publikováno v:
Infection and Immunity. 88
The translocated actin recruiting phosphoprotein (Tarp) is a multidomain type III secreted effector used by Chlamydia trachomatis In aggregate, existing data suggest a role of this effector in initiating new infections. As new genetic tools began to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bcd8a0f55ba3d6255dede197665f72ac
https://doi.org/10.1128/iai.00841-19
https://doi.org/10.1128/iai.00841-19
Autor:
Mitchell Thomas, Travis J. Jewett, Edgar Cruz, Jinho Park, Susmita Ghosh, Hyeran Kang, Omar A. Cardona
Publikováno v:
Biochemical and Biophysical Research Communications. 500:423-428
Chlamydia trachomatis entry into host cells is mediated by pathogen-directed remodeling of the actin cytoskeleton. The chlamydial type III secreted effector, translocated actin recruiting phosphoprotein (Tarp), has been implicated in the recruitment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91543979f066f27eae484e3f89973936
https://doi.org/10.1016/j.bbrc.2018.04.093
https://doi.org/10.1016/j.bbrc.2018.04.093