Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Travis J, Jewett"'
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
Chlamydia trachomatis is an obligate intracellular pathogen that actively promotes invasion of epithelial cells. A virulence-associated type III secretion system contributes to chlamydial entry and at least four effectors have been described that are
Externí odkaz:
https://doaj.org/article/d141021abeb24832a4a58a516e7391ca
Autor:
Madelyn H. Miller, Lindsay G. Swaby, Vanessa S. Vailoces, Maggie LaFratta, Yuan Zhang, Xiang Zhu, Dorilyn J. Hitchcock, Travis J. Jewett, Bin Zhang, Justine T. Tigno-Aranjuez
Publikováno v:
Cell Reports, Vol 42, Iss 3, Pp 112208- (2023)
Summary: Development of therapies with the potential to change the allergic asthmatic disease course will require the discovery of targets that play a central role during the initiation of an allergic response, such as those involved in the process o
Externí odkaz:
https://doaj.org/article/3e65c87a424c4584ac69991225803b72
Publikováno v:
PLoS ONE, Vol 18, Iss 6, p e0286959 (2023)
Colonization of a localized area of human skin by Borrelia burgdorferi after a bite from an infected tick is the first step in the development of Lyme disease. The initial interaction between the pathogen and the human host cells is suggested to impa
Externí odkaz:
https://doaj.org/article/97bf2f366908418bbc6d981972f20f2b
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
The intracellular pathogen Chlamydia trachomatis secretes multiple early effectors into the host cell to promote invasion. A key early effector during host cell entry, Tarp (translocated actin-recruiting phosphoprotein) is comprised of multiple prote
Externí odkaz:
https://doaj.org/article/b76c0a3b11614f5abd99c44adf766cd4
Autor:
Hunter W Kuhn, Amanda G Lasseter, Philip P Adams, Carlos Flores Avile, Brandee L Stone, Darrin R Akins, Travis J Jewett, Mollie W Jewett
Publikováno v:
PLoS Pathogens, Vol 17, Iss 8, p e1009869 (2021)
The Lyme disease spirochete Borrelia burgdorferi relies on uptake of essential nutrients from its host environments for survival and infection. Therefore, nutrient acquisition mechanisms constitute key virulence properties of the pathogen, yet these
Externí odkaz:
https://doaj.org/article/83133a61316f4c7694a6b07daadd1c8f
Publikováno v:
mBio, Vol 12, Iss 1 (2021)
The increasing genetic tractability of Chlamydia trachomatis
Externí odkaz:
https://doaj.org/article/4bc7b84c20da400db80bf02f0054c4f9
Publikováno v:
Frontiers in cellular and infection microbiology. 12
The intracellular pathogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::647720fc104984b41869d5c4958bbff7
https://pubmed.ncbi.nlm.nih.gov/35300377
https://pubmed.ncbi.nlm.nih.gov/35300377
Publikováno v:
Biochem Biophys Res Commun
Chlamydia trachomatis injects bacterial effector proteins into human epithelial cells to facilitate the establishment of new infections. The chlamydial type III secreted effector t ranslocated a ctin r ecruiting phospho p rotein (Tarp) has been shown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d1bb5f4f0a0e85e07b62a1518489702
https://europepmc.org/articles/PMC8206025/
https://europepmc.org/articles/PMC8206025/
Autor:
Elizabeth A. Ruelke, Maria Bodero, Susmita Ghosh, Kenneth A. Fields, Travis J. Jewett, Joshua C. Ferrell
Publikováno v:
Infection and Immunity. 88
The translocated actin recruiting phosphoprotein (Tarp) is a multidomain type III secreted effector used by Chlamydia trachomatis In aggregate, existing data suggest a role of this effector in initiating new infections. As new genetic tools began to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bcd8a0f55ba3d6255dede197665f72ac
https://doi.org/10.1128/iai.00841-19
https://doi.org/10.1128/iai.00841-19
Autor:
Mitchell Thomas, Travis J. Jewett, Edgar Cruz, Jinho Park, Susmita Ghosh, Hyeran Kang, Omar A. Cardona
Publikováno v:
Biochemical and Biophysical Research Communications. 500:423-428
Chlamydia trachomatis entry into host cells is mediated by pathogen-directed remodeling of the actin cytoskeleton. The chlamydial type III secreted effector, translocated actin recruiting phosphoprotein (Tarp), has been implicated in the recruitment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91543979f066f27eae484e3f89973936
https://doi.org/10.1016/j.bbrc.2018.04.093
https://doi.org/10.1016/j.bbrc.2018.04.093